(Q33688611)

28 July 2017

title

Plasma membrane subdomain compartmentalization contributes to distinct mechanisms of ceramide action on insulin signaling (English)

1 reference

28 July 2017

1 reference

1 reference

Cédric M Blouin

1

0 references

Isabelle Dugail

object named as

Isabelle Dugail

7

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Eric Hajduch

object named as

Eric Hajduch

8

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Pascal Ferré

object named as

Pascal Ferré

6

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author name string

Cécilia Prado

2

1 reference

28 July 2017

Karen K Takane

3

1 reference

28 July 2017

Françoise Lasnier

4

1 reference

28 July 2017

Adolfo Garcia-Ocana

5

1 reference

28 July 2017

language of work or name

English

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publication date

3 December 2009

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28 July 2017

number of pages

11

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inferred from page(s)

published in

Diabetes

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28 July 2017

volume

59

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28 July 2017

issue

3

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28 July 2017

page(s)

600-610

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

28 July 2017

copyright license

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

The carboxyl-terminal domain of atypical protein kinase Czeta binds to ceramide and regulates junction formation in epithelial cells

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Regulated association of caveolins to lipid droplets during differentiation of 3T3-L1 adipocytes

21 June 2018

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Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism

21 June 2018

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Targeting of PKCzeta and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide

21 June 2018

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Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes

21 June 2018

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Cellular spelunking: exploring adipocyte caveolae

21 June 2018

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Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

21 June 2018

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Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

21 June 2018

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The neck of caveolae is a distinct plasma membrane subdomain that concentrates insulin receptors in 3T3-L1 adipocytes

21 June 2018

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21 June 2018

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Modulation of the caveolin-3 and Akt status in caveolae by insulin resistance in H9c2 cardiomyoblasts

21 June 2018

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21 June 2018

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Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

21 June 2018

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21 June 2018

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Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

21 June 2018

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Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways

21 June 2018

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Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

21 June 2018

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

21 June 2018

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Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling

21 June 2018

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Ceramide: second messenger or modulator of membrane structure and dynamics?

21 June 2018

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21 June 2018

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Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes

21 June 2018

1 reference

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Lipid rafts and insulin signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Intracellular signalling mechanisms regulating glucose transport in insulin-sensitive tissues (review).

21 June 2018

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Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

21 June 2018

1 reference

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Protein kinase B (PKB/Akt)--a key regulator of glucose transport?

21 June 2018

1 reference

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Protein phosphatase 2A: the Trojan Horse of cellular signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

p70 S6 kinase is regulated by protein kinase Czeta and participates in a phosphoinositide 3-kinase-regulated signalling complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

21 June 2018

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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

21 June 2018

1 reference

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

A simplified system for generating recombinant adenoviruses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Functional rafts in cell membranes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Ceramide activates heterotrimeric protein phosphatase 2A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Expression and compartmentalization of caveolin in adipose cells: coordinate regulation with and structural segregation from GLUT4.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): implications for lipid raft structure and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828662

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19959757

12 December 2020

inferred from PubMed ID database lookup

Fluid-phase endocytosis by primary cultures of bovine brain microvessel endothelial cell monolayers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19959757

12 December 2020

inferred from PubMed ID database lookup

Exchange of C(16)-ceramide between phospholipid vesicles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19959757

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.2337/DB09-0897

1 reference

28 July 2017

1 reference

28 July 2017

1 reference