(Q24297416)

protein autophosphorylation

GOA release 2020-03-11

1 reference

Seminars in Cell & Developmental Biology

GOA release 2020-03-11

2

David Komander

David

Komander

1 reference

9 December 2023

Alfonso Mora

1

Alfonso

Mora

1 reference

9 December 2023

Dario R Alessi

4

Dario R

Alessi

1 reference

9 December 2023

Daan M F van Aalten

3

Daan M F

van Aalten

1 reference

9 December 2023

language of work or name

English

0 references

publication date

April 2004

0 references

published in

0 references

volume

15

0 references

page(s)

161-70

0 references

issue

2

0 references

cites work

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

The p70 S6 kinase integrates nutrient and growth signals to control translational capacity.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Integration of Growth Factor and Nutrient Signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Integration of growth factor and nutrient signaling: implications for cancer biology

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Role of S6 phosphorylation and S6 kinase in cell growth

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

The conformational plasticity of protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

PTEN: The down side of PI 3-kinase signalling.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Ten years of protein kinase B signalling: a hard Akt to follow

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Role of Akt/protein kinase B in metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

TSC1–TSC2: a complex tale of PKB-mediated S6K regulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Partial purification and characterization of a wortmannin-sensitive and insulin-stimulated protein kinase that activates heart 6-phosphofructo-2-kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Monitoring conformational changes of proteins in cells by fluorescence lifetime imaging microscopy

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Mechanisms of control of heart glycolysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

PDK1 regulates growth through Akt and S6K in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Czeta (PKCzeta ) and PKC-related kinase 2 by PDK1

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Requirement for 3-phosphoinositide-kependent dinase-1 (PDK-1) in insulin-induced glucose uptake in immortalized brown adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Essential role of PDK1 in regulating cell size and development in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021

The cell cycle as a target for cancer therapy: basic and clinical findings with the small molecule inhibitors flavopiridol and UCN-01.

1 reference

https://api.crossref.org/works/10.1016%2FJ.SEMCDB.2003.12.022

7 January 2021