Wikidata

(Q21114955)

English

3-phosphoinositide dependent protein kinase 1

mammalian protein found in Homo sapiens

  • PDPK1
  • 3-phosphoinositide-dependent protein kinase 2 pseudogene
  • PkB kinase like gene 1
  • 3-phosphoinositide-dependent protein kinase 1
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
7 references
retrieved
8 April 2019
stated in
TUSC4/NPRL2, a novel PDK1-interacting protein, inhibits PDK1 tyrosine phosphorylation and its downstream signaling
GOA
curator
UniProt
UniProt protein ID
O15530
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15530
determination method or standard
IPI
retrieved
8 April 2019
stated in
The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15530
determination method or standard
IPI
retrieved
8 April 2019
stated in
B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15530
determination method or standard
IPI
retrieved
8 April 2019
stated in
Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15530
determination method or standard
IPI
retrieved
8 April 2019
stated in
Visualization of biochemical networks in living cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15530
determination method or standard
IPI
retrieved
8 April 2019
stated in
Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15530
determination method or standard
IPI
retrieved
8 April 2019
stated in
The Mechanism of ATP-Dependent Allosteric Protection of Akt Kinase Phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15530
determination method or standard
IPI
protein serine/threonine kinase activity
determination method or standard
EXP
IBA
IDA
IEA
TAS
6 references
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15530&geneProductId=UniProtKB:O15530
determination method or standard
TAS
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O15530
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15530&geneProductId=UniProtKB:O15530
determination method or standard
IEA
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15530&geneProductId=UniProtKB:O15530
determination method or standard
IEA
retrieved
10 September 2018
stated in
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15530&geneProductId=UniProtKB:O15530
determination method or standard
IDA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15530&geneProductId=UniProtKB:O15530
determination method or standard
IBA
retrieved
10 September 2018
stated in
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O15530&geneProductId=UniProtKB:O15530
determination method or standard
EXP
cell component
biological process

Identifiers

PDB structure ID
 
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