(Q33691942)

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Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

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scholarly article

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Europe PubMed Central

28 July 2017

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation (English)

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Europe PubMed Central

28 July 2017

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Kimberly Stegmaier

17

object named as

Kimberly Stegmaier

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28 July 2017

12

object named as

Gabriela Alexe

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28 July 2017

Sébastien Malinge

object named as

Sébastien Malinge

15

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John D Crispino

object named as

John D Crispino

29

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Geertruy Te Kronnie

object named as

Geertruy te Kronnie

20

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28

object named as

William C Hahn

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28 July 2017

Anna C Schinzel

13

object named as

Anna C Schinzel

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David M Weinstock

31

object named as

David M Weinstock

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24

object named as

Donna Neuberg

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28 July 2017

author name string

Andrew A Lane

1

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28 July 2017

Bjoern Chapuy

2

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28 July 2017

Charles Y Lin

3

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28 July 2017

Trevor Tivey

4

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28 July 2017

Hubo Li

5

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Elizabeth C Townsend

6

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Diederik van Bodegom

7

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Tovah A Day

8

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Shuo-Chieh Wu

9

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Huiyun Liu

10

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Akinori Yoda

11

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Timothy J Sullivan

14

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Jordan E Taylor

16

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Jacob D Jaffe

18

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Michael Bustin

19

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Shai Izraeli

21

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Marian H Harris

22

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Kristen E Stevenson

23

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Lewis B Silverman

25

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Stephen E Sallan

26

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James E Bradner

27

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David Pellman

30

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28 July 2017

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publication date

20 April 2014

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28 July 2017

Nature Genetics

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46

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28 July 2017

6

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618-623

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28 July 2017

https://scigraph.springernature.com/pub.10.1038/ng.2949

0 references

Selective inhibition of tumor oncogenes by disruption of super-enhancers

1 reference

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Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

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Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.

1 reference

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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

1 reference

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Quantitative assessment of chromatin immunoprecipitation grade antibodies directed against histone modifications reveals patterns of co-occurring marks on histone protein molecules

1 reference

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14 July 2018

The chromatin-binding protein HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2) and affects the behavior of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

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Repair at single targeted DNA double-strand breaks in pluripotent and differentiated human cells

1 reference

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Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome

1 reference

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14 July 2018

Effects of HMGN variants on the cellular transcription profile

1 reference

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Enrichment map: a network-based method for gene-set enrichment visualization and interpretation

1 reference

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Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2

1 reference

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14 July 2018

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

14 July 2018

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

1 reference

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14 July 2018

Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

14 July 2018

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

1 reference

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14 July 2018

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

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14 July 2018

Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

14 July 2018

CEAS: cis-regulatory element annotation system

1 reference

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14 July 2018

Mutational spectrum at GATA1 provides insights into mutagenesis and leukemogenesis in Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

14 July 2018

Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

14 July 2018

HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

14 July 2018

JAK mutations in high-risk childhood acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

14 July 2018

Malignancy in children with trisomy 21.

1 reference

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14 July 2018

Model-based analysis of ChIP-Seq (MACS)

1 reference

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14 July 2018

Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance

1 reference

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14 July 2018

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

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Robust, persistent transgene expression in human embryonic stem cells is achieved with AAVS1-targeted integration

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Moderated statistical tests for assessing differences in tag abundance

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Small-sample estimation of negative binomial dispersion, with applications to SAGE data

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

1 reference

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14 July 2018

Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells

1 reference

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14 July 2018

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GenePattern 2.0

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14 July 2018

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

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Alternative pathways for the repair of RAG-induced DNA breaks

1 reference

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Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

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14 July 2018

Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040006

14 July 2018

A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

1 reference

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14 July 2018

Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin

1 reference

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14 July 2018

Competition between histone H1 and HMGN proteins for chromatin binding sites.

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14 July 2018

Characterization of transgenic mice with an increased content of chromosomal protein HMG-14 in their chromatin

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

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14 July 2018

IgH enhancer-mediated deregulation of N-myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c-myc expression

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Immunochemical analysis of the exposure of high mobility group protein 14 and 17 surfaces in chromatin.

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Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1 reference

https://pubmed.ncbi.nlm.nih.gov/24747640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional expression and germline transmission of a human chromosome fragment in chimaeric mice

1 reference

https://api.crossref.org/works/10.1038%2FNG.2949

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/NG.2949

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Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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