(Q33694368)

28 July 2017

Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation (English)

1 reference

28 July 2017

1 reference

8

Christopher M Dobson

1 reference

28 July 2017

5

Michele Vendruscolo

1 reference

28 July 2017

Céline Galvagnion

2

0 references

Alexander K Buell

Alexander K Buell

1

0 references

Emma Sparr

Emma Sparr

4

0 references

Sara Snogerup Linse

Sara Linse

7

0 references

Tuomas Knowles

6

Tuomas P J Knowles

1 reference

28 July 2017

Ricardo Gaspar

3

1 reference

PubMed ID

24817693

28 July 2017

language of work or name

English

0 references

publication date

9 May 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

1 reference

28 July 2017

111

1 reference

28 July 2017

21

1 reference

28 July 2017

7671-7676

1 reference

An imaging and systems modeling approach to fibril breakage enables prediction of amyloid behavior

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Membrane interaction of α-synuclein in different aggregation states

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Role of elongation and secondary pathways in S6 amyloid fibril growth.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Direct observation of the interconversion of normal and toxic forms of α-synuclein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

From macroscopic measurements to microscopic mechanisms of protein aggregation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Nucleated polymerisation in the presence of pre-formed seed filaments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Low-resolution structure of a vesicle disrupting α-synuclein oligomer that accumulates during fibrillation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

NMR determination of pKa values in α-synuclein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Alpha-synuclein in alpha-helical conformation at air-water interface: implication of conformation and orientation changes during its accumulation/aggregation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Strategies to increase the reproducibility of protein fibrillization in plate reader assays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

An analytical solution to the kinetics of breakable filament assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Fiber-dependent amyloid formation as catalysis of an existing reaction pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Protein misfolding, functional amyloid, and human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Mechanism of prion propagation: amyloid growth occurs by monomer addition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Nucleated conformational conversion and the replication of conformational information by a prion determinant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Kinetics of sickle hemoglobin polymerization. II. A double nucleation mechanism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

Rapid Anionic Micelle-mediated α-Synuclein Fibrillization in Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

In vitro formation of amyloid from alpha-synuclein is dominated by reactions at hydrophobic interfaces.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

Amyloid nucleation triggered by agitation of beta2-microglobulin under acidic and neutral pH conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

SDS-induced fibrillation of alpha-synuclein: an alternative fibrillation pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

Dependence of alpha-synuclein aggregate morphology on solution conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

Measurement and modelling of sequence-specific pKa values of lysine residues in calbindin D9k

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040554

30 October 2018

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

Frequency Factors in a Landscape Model of Filamentous Protein Aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

Detailed Analysis of the Energy Barriers for Amyloid Fibril Growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1315346111

The presence of an air-water interface affects formation and elongation of α-Synuclein fibrils

21 January 2018

1 reference

12 December 2020

Fibrillogenic and non-fibrillogenic ensembles of SDS-bound human alpha-synuclein

1 reference

12 December 2020

Nucleation of amyloid fibrils

1 reference

12 December 2020

Atomic force microscopy under controlled conditions reveals structure of C-terminal region of α-synuclein in amyloid fibrils

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1315346111

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference

PubMed ID

24817693