(Q41837825)

12 October 2017

An imaging and systems modeling approach to fibril breakage enables prediction of amyloid behavior (English)

1 reference

12 October 2017

1

1 reference

12 October 2017

2

1 reference

PMCID

3882454

12 October 2017

language of work or name

English

0 references

publication date

1 December 2013

1 reference

12 October 2017

9

1 reference

full work available at URL

inferred from page(s)

http://eprints.whiterose.ac.uk/80191/

content deliverer

White Rose Research Online

object has role

published version

copyright license

Creative Commons Attribution-NonCommercial 2.0 Generic

0 references

https://doi.org/10.1016/j.bpj.2013.10.034

copyright license

Creative Commons Attribution-NonCommercial 2.0 Generic

0 references

1 reference

12 October 2017

105

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12 October 2017

12

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12 October 2017

2811-2819

1 reference

Aggregation modulators interfere with membrane interactions of β2-microglobulin fibrils

12 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Mechanistic and environmental control of the prevalence and lifetime of amyloid oligomers

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Direct three-dimensional visualization of membrane disruption by amyloid fibrils

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Amyloid β-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Direct observation of the interconversion of normal and toxic forms of α-synuclein

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

The amyloid state of proteins in human diseases

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Effect of sequence variation on the mechanical response of amyloid fibrils probed by steered molecular dynamics simulation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

The seeds of neurodegeneration: prion-like spreading in ALS

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Nanomechanics of functional and pathological amyloid materials.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

A diversity of assembly mechanisms of a generic amyloid fold

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Mysterious oligomerization of the amyloidogenic proteins

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Fibril fragmentation in amyloid assembly and cytotoxicity: when size matters

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Ester to amide switch peptides provide a simple method for preparing monomeric islet amyloid polypeptide under physiologically relevant conditions and facilitate investigations of amyloid formation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

An analytical solution to the kinetics of breakable filament assembly

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Fibril fragmentation enhances amyloid cytotoxicity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Amyloid fibril length distribution quantified by atomic force microscopy single-particle image analysis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Functional amyloids as natural storage of peptide hormones in pituitary secretory granules

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

The number and transmission of [PSI] prion seeds (Propagons) in the yeast Saccharomyces cerevisiae

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Functional amyloid--from bacteria to humans.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Protein misfolding, functional amyloid, and human disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

The kinetics of nucleated polymerizations at high concentrations: amyloid fibril formation near and above the "supercritical concentration".

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Mechanism of prion propagation: amyloid growth occurs by monomer addition

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Length dependence of rate constants for end-to-end association and dissociation of equilibrium linear aggregates

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Kinetics of sickle hemoglobin polymerization. II. A double nucleation mechanism.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

The physical basis of how prion conformations determine strain phenotypes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Analysis of protein aggregation kinetics.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Beta-2-microglobulin-associated amyloidosis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Stop-and-go kinetics in amyloid fibrillation

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Amyloid Fibrils of Mammalian Prion Protein Are Highly Toxic to Cultured Cells and Primary Neurons

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882454

Understanding amyloid aggregation by statistical analysis of atomic force microscopy images

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24359753

12 December 2020

inferred from PubMed ID database lookup

Nucleation of amyloid fibrils

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24359753

12 December 2020

inferred from PubMed ID database lookup

Ultrasonication-dependent acceleration of amyloid fibril formation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24359753

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.BPJ.2013.10.034

1 reference

12 October 2017

0 references

1 reference

12 October 2017

1 reference

PMCID

3882454