(Q37803276)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20977664%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20977664%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20977664%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

author name string

Massimo Stefani

series ordinal

1

1 reference

23 August 2017

language of work or name

English

0 references

publication date

1 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20977664%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20977664%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

277

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20977664%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20977664%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

page(s)

4602-4613

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20977664%20AND%20SRC:MED&resulttype=core&format=json

Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

14 January 2020

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Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

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Oligomer-specific Abeta toxicity in cell models is mediated by selective uptake

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21 January 2018

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Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F.

21 January 2018

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Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

21 January 2018

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Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

21 January 2018

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Evidence for proteotoxicity in beta cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway

21 January 2018

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The protofilament structure of insulin amyloid fibrils

21 January 2018

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3D structure of Alzheimer's amyloid-beta(1-42) fibrils

21 January 2018

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Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

21 January 2018

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Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure

21 January 2018

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Role of small oligomers on the amyloidogenic aggregation free-energy landscape

21 January 2018

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Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils

21 January 2018

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Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization

21 January 2018

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Characterization of oligomers during alpha-synuclein aggregation using intrinsic tryptophan fluorescence

21 January 2018

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Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils

21 January 2018

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Nucleated conformational conversion and the replication of conformational information by a prion determinant

21 January 2018

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Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates

21 January 2018

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Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation

21 January 2018

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Amyloid formation by globular proteins under native conditions

21 January 2018

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Amyloid fibril formation can proceed from different conformations of a partially unfolded protein

21 January 2018

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Emerging principles of conformation-based prion inheritance

21 January 2018

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers

21 January 2018

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A causative link between the structure of aberrant protein oligomers and their toxicity.

21 January 2018

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Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

21 January 2018

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Abeta42 mutants with different aggregation profiles induce distinct pathologies in Drosophila

21 January 2018

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21 January 2018

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21 January 2018

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Pore-forming proteins share structural and functional homology with amyloid oligomers

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Polymorphism of Alzheimer's Abeta17-42 (p3) oligomers: the importance of the turn location and its conformation

21 January 2018

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Structure-neurotoxicity relationships of amyloid beta-protein oligomers

21 January 2018

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Simulations as analytical tools to understand protein aggregation and predict amyloid conformation

21 January 2018

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Macromolecular crowding: an important but neglected aspect of the intracellular environment

21 January 2018

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Two types of Alzheimer's beta-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation.

21 January 2018

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Heparin accelerates gelsolin amyloidogenesis

21 January 2018

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Sulfated polysaccharides promote the assembly of amyloid beta(1-42) peptide into stable fibrils of reduced cytotoxicity

21 January 2018

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Generic cell dysfunction in neurodegenerative disorders: role of surfaces in early protein misfolding, aggregation, and aggregate cytotoxicity.

21 January 2018

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Protein structural perturbation and aggregation on homogeneous surfaces

21 January 2018

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The yeast prion Ure2p native-like assemblies are toxic to mammalian cells regardless of their aggregation state.

21 January 2018

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Binding of endostatin to phosphatidylserine-containing membranes and formation of amyloid-like fibers.

21 January 2018

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Formation of amyloid fibers triggered by phosphatidylserine-containing membranes

21 January 2018

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Cholesterol in Alzheimer's disease: unresolved questions.

21 January 2018

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Formation of amyloids by Abeta-(1-42) on NGF-differentiated PC12 cells: roles of gangliosides and cholesterol

21 January 2018

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Ganglioside-induced amyloid formation by human islet amyloid polypeptide in lipid rafts

21 January 2018

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Seladin-1/DHCR24 protects neuroblastoma cells against Abeta toxicity by increasing membrane cholesterol content

21 January 2018

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Cholesterol homeostasis failure as a unifying cause of synaptic degeneration

21 January 2018

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Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

21 January 2018

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Fibril fragmentation enhances amyloid cytotoxicity

21 January 2018

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Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice

21 January 2018

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Interaction of the anthracycline 4'-iodo-4'-deoxydoxorubicin with amyloid fibrils: inhibition of amyloidogenesis

21 January 2018

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Doxycycline disrupts transthyretin amyloid: evidence from studies in a FAP transgenic mice model.

21 January 2018

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Molecular recycling within amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07889.X

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life

21 January 2018

1 reference

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Characterization of the nanoscale properties of individual amyloid fibrils

21 January 2018

1 reference

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Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils.

21 January 2018

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A single disulfide bond differentiates aggregation pathways of beta2-microglobulin.

21 January 2018

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Identification of physiological and toxic conformations in Abeta42 aggregates.

21 January 2018

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Role of aggregation conditions in structure, stability, and toxicity of intermediates in the Abeta fibril formation pathway

21 January 2018

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Structural transitions associated with the interaction of Alzheimer beta-amyloid peptides with gangliosides.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07889.X

Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07889.X

Annular alpha-synuclein oligomers are potentially toxic agents in alpha-synucleinopathy. Hypothesis

21 January 2018

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Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates.

21 January 2018

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Selective vulnerability of different types of commissural neurons for amyloid beta-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology.

21 January 2018

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Amyloid Fibrils of Mammalian Prion Protein Are Highly Toxic to Cultured Cells and Primary Neurons

21 January 2018

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Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07889.X

Lysozyme Amyloid Oligomers and Fibrils Induce Cellular Death via Different Apoptotic/Necrotic Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07889.X