(Q33695077)

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The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression

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scholarly article

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Europe PubMed Central

28 July 2017

The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression (English)

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Europe PubMed Central

28 July 2017

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5

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1 June 2020

author name string

M S Becker

1

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1 June 2020

P Schmezer

2

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1 June 2020

R Breuer

3

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1 June 2020

S F Haas

4

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1 June 2020

P H Krammer

6

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1 June 2020

M Li-Weber

7

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1 June 2020

publication date

16 January 2014

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28 July 2017

Cell Death and Disease

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1 June 2020

5

1 reference

Europe PubMed Central

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1 June 2020

e1000

1 reference

Europe PubMed Central

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1 June 2020

https://scigraph.springernature.com/pub.10.1038/cddis.2013.528

0 references

Evidence for a functionally relevant rocaglamide binding site on the eIF4A-RNA complex

1 reference

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21 June 2018

Evaluation of different biomarkers to predict individual radiosensitivity in an inter-laboratory comparison--lessons for future studies

1 reference

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21 June 2018

The natural anticancer compounds rocaglamides inhibit the Raf-MEK-ERK pathway by targeting prohibitin 1 and 2

1 reference

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21 June 2018

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

1 reference

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21 June 2018

Mdm2 and MdmX partner to regulate p53.

1 reference

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21 June 2018

The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage

1 reference

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21 June 2018

DNA damage-induced cell death: from specific DNA lesions to the DNA damage response and apoptosis

1 reference

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21 June 2018

Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53

1 reference

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21 June 2018

Flavaglines alleviate doxorubicin cardiotoxicity: implication of Hsp27

1 reference

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21 June 2018

Chemistry and biology of rocaglamides (= flavaglines) and related derivatives from aglaia species (meliaceae)

1 reference

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21 June 2018

Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression

1 reference

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21 June 2018

Rocaglamide breaks TRAIL resistance in HTLV-1-associated adult T-cell leukemia/lymphoma by translational suppression of c-FLIP expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

The multiple levels of regulation by p53 ubiquitination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Mdm2-mediated ubiquitylation: p53 and beyond.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Rocaglamide sensitizes leukemic T cells to activation-induced cell death by differential regulation of CD95L and c-FLIP expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

GammaH2AX and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Tumour cell survival signalling by the ERK1/2 pathway

1 reference

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21 June 2018

Differential effects of chemotherapeutic drugs versus the MDM-2 antagonist nutlin-3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

DNA damage-induced cell death by apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

The p53 family in nervous system development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Bim is a suppressor of Myc-induced mouse B cell leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Chemotherapy-induced neutropenia: risks, consequences, and new directions for its management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Live or let die: the cell's response to p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaia elliptica.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Screening the p53 status of human cell lines using a yeast functional assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

21 June 2018

Etoposide: A Semisynthetic Epipodophyllotoxin Chemistry, Pharmacology, Pharmacokinetics, Adverse Effects and Use as an Antineoplastic Agent

1 reference

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21 June 2018

Quantitative Relationships Between Circulating Leukocytes and Infection in Patients with Acute Leukemia

1 reference

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21 June 2018

Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines

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21 June 2018

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

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21 June 2018

Radioprotective potential of an herbal extract of Tinospora cordifolia

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

21 January 2018

Effects of antioxidant herbs on chemotherapy-induced nausea and vomiting in a rat-pica model.

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

21 January 2018

The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

21 January 2018

Phase I/IIA randomized study of PHY906, a novel herbal agent, as a modulator of chemotherapy in patients with advanced colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

21 January 2018

The use of Chinese herbal medicine to improve quality of life in women undergoing chemotherapy for ovarian cancer: a double-blind placebo-controlled randomized trial with immunological monitoring.

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

21 January 2018

Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

21 January 2018

A synthetic derivative of the natural product rocaglaol is a potent inhibitor of cytokine-mediated signaling and shows neuroprotective activity in vitro and in animal models of Parkinson's disease and traumatic brain injury.

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

21 January 2018

Activation interferes with the APO-1 pathway in mature human T cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

21 January 2018

Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040689

30 October 2018

Radioprotective effects of two traditional Chinese medicine prescriptions: si-wu-tang and si-jun-zi-tang

1 reference

https://pubmed.ncbi.nlm.nih.gov/24434508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphocyte depletion during treatment with intensive chemotherapy for cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24434508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of atm radiosensitizes multiple p53 null tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/24434508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysfunctional p53 deletion mutants in cell lines derived from Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24434508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavaglines as potent anticancer and cytoprotective agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/24434508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-Ray crystal structure of rocaglamide, a novel antileulemic 1H-cyclopenta[b]benzofuran from Aglaia elliptifolia

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2013.528

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CDDIS.2013.528

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24434508%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24434508%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24434508%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

ResearchGate publication ID

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