(Q36521923)

14 August 2017

1 reference

title

The p53 family in nervous system development and disease (English)

1 reference

14 August 2017

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3

Freda D Miller

1 reference

14 August 2017

W Bradley Jacobs

1

1 reference

PubMed ID

16805769

14 August 2017

David R Kaplan

series ordinal

2

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PubMed ID

16805769

14 August 2017

language of work or name

English

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publication date

1 June 2006

1 reference

Journal of Neurochemistry

14 August 2017

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14 August 2017

97

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14 August 2017

6

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14 August 2017

1571-1584

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p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

14 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Analysis of the effects of the antiserum to the nerve growth factor in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

High-frequency developmental abnormalities in p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Mitochondria, free radicals, and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Short- and long-term effects of nerve growth factor on the sympathetic nervous system in the adult mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p53 isoforms can regulate p53 transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p53 expression in brain after middle cerebral artery occlusion in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Requirement for a functional Rb-1 gene in murine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p53 in neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Two new p73 splice variants, gamma and delta, with different transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

BAX is required for neuronal death after trophic factor deprivation and during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

MEKK1/JNK signaling stabilizes and activates p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Biochemical effects of antibodies against nerve growth factor on developing and differentiated sympathetic ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Programmed cell death in cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Death of some dorsal root ganglion neurons and plasticity of others following sciatic nerve section in adult and neonatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Neurotrophins: roles in neuronal development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Perp is a p63-regulated gene essential for epithelial integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Effects of an Rb mutation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p63 is an essential proapoptotic protein during neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Peg3/Pw1 is a mediator between p53 and Bax in DNA damage-induced neuronal death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Apoptosis: a link between cancer genetics and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Neurotrophin signal transduction in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Noxa is a critical mediator of p53-dependent motor neuron death after nerve injury in adult mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p63 is the molecular switch for initiation of an epithelial stratification program

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Molecular basis of programmed cell death involved in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

T antigen is bound to a host protein in SY40-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

A dominant-negative form of p63 is required for epidermal proliferation in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Evidence that DeltaNp73 promotes neuronal survival by p53-dependent and p53-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Three distinct signalling responses by murine fibroblasts to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Delayed loss of spinal motoneurons after peripheral nerve injury in adult rats: a quantitative morphological study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Pin1 links the activities of c-Abl and p300 in regulating p73 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p73: Friend or foe in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Functional regulation of p73 and p63: development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The p53-Mdm2 module and the ubiquitin system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p53 has a direct apoptogenic role at the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

On Trk for retrograde signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Neuronal life and death: an essential role for the p53 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p63: oncogene or tumor suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p53-dependent cell death signaling in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Blocking cytochrome c activity within intact neurons inhibits apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Decision making by p53: life, death and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Immunization of adult rats against 2.5 S NGF: Effects on the peripheral sympathetic nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p53 induction is associated with neuronal damage in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

c-Abl: activation and nuclear targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Immunohistochemical study of p53-associated proteins in rat brain following lithium-pilocarpine status epilepticus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The linchpin? Pin1 meets p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The invulnerability of adult neurons: a critical role for p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Increase in p53 protein expression following cortical infarction in the spontaneously hypertensive rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The p53 homologue p73 accumulates in the nucleus and localizes to neurites and neurofibrillary tangles in Alzheimer disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The BH3-only protein Puma is both necessary and sufficient for neuronal apoptosis induced by DNA damage in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

On the shoulders of giants: p63, p73 and the rise of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Apoptosis in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Diversity in the mechanisms of neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants ε and ζ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.03980.X

10.1111/J.1471-4159.2006.03980.X

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16805769