(Q33701588)

28 July 2017

Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells (English)

1 reference

28 July 2017

1 reference

Nameeta Mujumdar

1

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28 July 2017

Sulagna Banerjee

2

1 reference

28 July 2017

Zhiyu Chen

3

1 reference

28 July 2017

Veena Sangwan

4

1 reference

28 July 2017

Rohit Chugh

5

1 reference

28 July 2017

Vikas Dudeja

6

1 reference

28 July 2017

Masato Yamamoto

7

1 reference

28 July 2017

Selwyn M Vickers

8

1 reference

28 July 2017

Ashok K Saluja

9

1 reference

28 July 2017

3 April 2014

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American Journal of Physiology - Gastrointestinal and Liver Physiology

28 July 2017

1 reference

28 July 2017

306

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28 July 2017

11

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28 July 2017

G1011-20

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4042112/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Identification of a novel endoplasmic reticulum stress response element regulated by XBP1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Triptolide induces the expression of miR-142-3p: a negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Minnelide reduces tumor burden in preclinical models of osteosarcoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Triptolide-mediated cell death in neuroblastoma occurs by both apoptosis and autophagy pathways and results in inhibition of nuclear factor-kappa B activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Knockdown of glucose-regulated protein 78 decreases the invasion, metalloproteinase expression and ECM degradation in hepatocellular carcinoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Targeting phosphorylation of eukaryotic initiation factor-2α to treat human disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Mechanisms of ER stress-induced apoptosis in atherosclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

The expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large b-cell lymphoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Triptolide and TRAIL combination enhances apoptosis in cholangiocarcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Global patterns of cancer incidence and mortality rates and trends

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Endoplasmic reticulum stress response in cancer: molecular mechanism and therapeutic potential.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Autophagy and the functional roles of Atg5 and beclin-1 in the anti-tumor effects of 3beta androstene 17alpha diol neuro-steroid on malignant glioma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Heat shock protein 70 inhibits apoptosis in cancer cells through simultaneous and independent mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

The PERK/eIF2 alpha signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Signal integration in the endoplasmic reticulum unfolded protein response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4042112

Unfolded protein response activation contributes to chemoresistance in hepatocellular carcinoma

21 June 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00466.2013

Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00466.2013

The UPR as a survival factor of cancer cells: More than folding proteins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00466.2013

Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00466.2013

Overexpression of glucose-regulated protein 78 in colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00466.2013

Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis

21 January 2018

1 reference

12 December 2020

XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy

1 reference

12 December 2020

Glucose-regulated protein 78 expression in urothelial carcinoma of the upper urinary tract

1 reference

12 December 2020

Molecular chaperones and the heat shock response. Sponsored by Cold Spring Harbor Laboratory, 6-10 May 1998

1 reference

12 December 2020

Overexpression of GRP78 is associated with malignant transformation in epithelial ovarian tumors

1 reference

12 December 2020

Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1152/AJPGI.00466.2013

1 reference

28 July 2017

1 reference

28 July 2017

1 reference