(Q33702325)

28 July 2017

title

Methylnaltrexone potentiates the anti-angiogenic effects of mTOR inhibitors (English)

1 reference

28 July 2017

main subject

angiogenesis inhibitor

1 reference

7

Ravi Salgia

1 reference

28 July 2017

Patrick A Singleton

1

1 reference

28 July 2017

Nurbek Mambetsariev

2

1 reference

28 July 2017

Frances E Lennon

3

1 reference

28 July 2017

Biji Mathew

4

1 reference

28 July 2017

Jessica H Siegler

5

1 reference

28 July 2017

Liliana Moreno-Vinasco

6

1 reference

28 July 2017

Jonathan Moss

8

1 reference

28 July 2017

Joe Gn Garcia

9

1 reference

28 July 2017

language of work or name

1 reference

19 February 2010

1 reference

Journal of angiogenesis research

28 July 2017

published in

1 reference

28 July 2017

volume

2

1 reference

28 July 2017

issue

1

1 reference

28 July 2017

page(s)

5

1 reference

Methylnaltrexone for treatment of opioid-induced constipation in advanced illness patients

28 July 2017

cites work

1 reference

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PI3K and mTOR inhibitors: a new generation of targeted anticancer agents

21 June 2018

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Temsirolimus in patients with advanced renal cell carcinoma: an overview

21 June 2018

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Drug approvals: '08 in review. Methylnaltrexone (Relistor).

21 June 2018

1 reference

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Development of peripheral opioid antagonists' new insights into opioid effects

21 June 2018

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Membrane glycoproteins associated with breast tumor cell progression identified by a lectin affinity approach

21 June 2018

1 reference

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Temsirolimus, an mTOR inhibitor for treatment of patients with advanced renal cell carcinoma

21 June 2018

1 reference

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Mechanisms of Disease: survival benefit of temsirolimus validates a role for mTOR in the management of advanced RCC.

21 June 2018

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Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis

21 June 2018

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Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies

21 June 2018

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Methylnaltrexone for opioid-induced constipation in advanced illness

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase.

21 June 2018

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Targeted therapy for renal cell carcinoma: a new treatment paradigm

21 June 2018

1 reference

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AKT/PKB signaling: navigating downstream

21 June 2018

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The mammalian target of rapamycin signaling pathway: twists and turns in the road to cancer therapy

21 June 2018

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Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Current development of mTOR inhibitors as anticancer agents

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Protein tyrosine phosphatases and signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Redox regulation of protein-tyrosine phosphatases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Preclinical studies of opioids and opioid antagonists on gastrointestinal function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Protein tyrosine phosphatase 1B inhibition: opportunities and challenges

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Molecular design and biological activities of protein-tyrosine phosphatase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Drug synergism: its detection and applications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Regulation of Akt/PKB activation by tyrosine phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Potentiation of insulin-related signal transduction by a novel protein-tyrosine phosphatase inhibitor, Et-3,4-dephostatin, on cultured 3T3-L1 adipocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Plasma morphine concentrations during chronic oral administration in patients with cancer pain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Opioid Agonist-Antagonist Drugs in Acute and Chronic Pain States

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Kinetics of intravenous and intramuscular morphine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Subcutaneous methylnaltrexone for the treatment of opioid-induced constipation in patients with advanced illness: a double-blind, randomized, parallel group, dose-ranging study

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Tolerability, gut effects, and pharmacokinetics of methylnaltrexone following repeated intravenous administration in humans

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Endothelial contraction and monolayer hyperpermeability are regulated by Src kinase

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Methylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trial.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Peak plasma concentrations after oral morphine: a systematic review

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Transactivation of Sphingosine 1-Phosphate Receptors Is Essential for Vascular Barrier Regulation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2831839

Signaling pathways mediating VEGF165-induced calcium transients and membrane depolarization in human endothelial cells

10 December 2018

1 reference

12 December 2020

Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. II. Structure determination

1 reference

12 December 2020

Methylnaltrexone: the answer to opioid-induced constipation?

1 reference

12 December 2020

mTOR inhibitors in the treatment of cancer

1 reference

12 December 2020

Methylnaltrexone (Relistor) for opioid induced constipation

1 reference

12 December 2020

Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: role of receptor transactivation

1 reference

12 December 2020

Identifiers

DOI

10.1186/2040-2384-2-5

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference