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Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

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19 March 2020

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Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart (English)

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coronary artery disease

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19 March 2019

22 March 2019

17 June 2019

myocardial ischemia

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25 June 2019

8 September 2019

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25 September 2020

14 November 2020

8 December 2020

24 December 2020

7 April 2021

regulation of gene expression

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8 September 2019

biomedical investigative technique

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genetic epigenesis

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25 September 2020

precision medicine

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14 November 2020

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gene expression profiling

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7 April 2021

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Albert-László Barabási

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Sean M. Davidson

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Stefanie Dimmeler

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Rosalinda Madonna

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Cinzia Perrino

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Leon De Windt

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Derek John Hausenloy

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Joost Petrus Geradus Sluijter

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Thomas Thum

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Kirsti Ytrehus

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Péter Ferdinandy

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Cardiovascular Research

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22 March 2019

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Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart.

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Single-Cell Resolution of Temporal Gene Expression during Heart Development

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An 'Omics' Perspective on Cardiomyopathies and Heart Failure

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DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy.

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Cardiovascular effects of histone deacetylase inhibitors epigenetic therapies: Systematic review of 62 studies and new hypotheses for future research.

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14 July 2018

Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure

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Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression

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Harnessing the microRNA pathway for cardiac regeneration.

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Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations

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Transformative Impact of Proteomics on Cardiovascular Health and Disease: A Scientific Statement From the American Heart Association

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Cardioprotection in ischaemia-reperfusion injury: novel mechanisms and clinical translation

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Deciphering the Epigenetic Code of Cardiac Myocyte Transcription.

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Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry.

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14 July 2018

Epigenetic modifications and noncoding RNAs in cardiac hypertrophy and failure

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14 July 2018

Functional Genomics of Cardioprotection by Ischemic Conditioning and the Influence of Comorbid Conditions: Implications in Target Identification

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14 July 2018

Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association

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14 July 2018

Readers, writers, and erasers: chromatin as the whiteboard of heart disease

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14 July 2018

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.

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14 July 2018

Disease networks. Uncovering disease-disease relationships through the incomplete interactome

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Long noncoding RNAs and microRNAs in cardiovascular pathophysiology

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Tissue-specific Gene Expression in Rat Hearts and Aortas in a Model of Vascular Nitrate Tolerance

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Cardiovascular transcriptomics and epigenomics using next-generation sequencing: challenges, progress, and opportunities

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Genomics and Proteomics. Roadmap to the epitranscriptome.

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Progress in mitochondrial epigenetics

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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

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ESC working group cellular biology of the heart: position paper: improving the preclinical assessment of novel cardioprotective therapies

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Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease.

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Interaction of risk factors, comorbidities, and comedications with ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote conditioning

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The emerging role of epigenetics in cardiovascular disease

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Epigenome-wide association study of fasting blood lipids in the Genetics of Lipid-lowering Drugs and Diet Network study

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Proteomics and metabolomics for mechanistic insights and biomarker discovery in cardiovascular disease

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Sizing up models of heart failure: Proteomics from flies to humans.

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microRNAs in cardiovascular diseases: current knowledge and the road ahead.

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Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support

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Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy.

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Bioinformatic analysis of microarray data reveals several key genes related to heart failure

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Mapping human epigenomes

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Coronary heart disease is associated with a mutation in mitochondrial tRNA.

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mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts

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HDAC-dependent ventricular remodeling

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Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review

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Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats

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Glycemic memory

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14 July 2018

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14 July 2018

MicroRNAs involved in the mitogen-activated protein kinase cascades pathway during glucose-induced cardiomyocyte hypertrophy

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14 July 2018

Differentially expressed microRNAs and their target genes in the hearts of streptozotocin-induced diabetic mice

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The Mitoscriptome in Aging and Disease.

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Interactome networks and human disease

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Network medicine: a network-based approach to human disease

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Cardiovascular epigenetics: basic concepts and results from animal and human studies

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14 July 2018

Cardiac gene expression and systemic cytokine profile are complementary in a murine model of post-ischemic heart failure

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14 July 2018

Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure

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14 July 2018

The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences

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14 July 2018

Epigenetics: a molecular link between environmental factors and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Energetics, epigenetics, mitochondrial genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Systemic evaluation of gene expression changes in major target organs induced by atorvastatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Uncomplicated human obesity is associated with a specific cardiac transcriptome: involvement of the Wnt pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Comparing genomic expression patterns across species identifies shared transcriptional profile in aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Gene activity changes in ischemically preconditioned rabbit heart gene: discovery array study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Initial sequencing and analysis of the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

14 July 2018

Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Proteomics and metabolomics in biomarker discovery for cardiovascular diseases: progress and potential.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Identification of a gene expression profile that differentiates between ischemic and nonischemic cardiomyopathy.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Transcriptomal analysis of failing and nonfailing human hearts.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Genomic analysis reveals poor separation of human cardiomyopathies of ischemic and nonischemic etiologies.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Effect of classic preconditioning on the gene expression pattern of rat hearts: a DNA microarray study

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

The remote ischemic preconditioning stimulus modifies gene expression in mouse myocardium.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Cardiac gene expression profile in rats with terminal heart failure and cachexia

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Gene expression profiling from endomyocardial biopsy tissue allows distinction between subentities of dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Age related changes in 5-methylcytosine content in human peripheral leukocytes and placentas: an HPLC-based study

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Cholesterol diet-induced hyperlipidemia influences gene expression pattern of rat hearts: a DNA microarray study

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Kinetic analysis of cardiac transcriptome regulation during chronic high-fat diet in dogs.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

MicroRNA-25-dependent up-regulation of NADPH oxidase 4 (NOX4) mediates hypercholesterolemia-induced oxidative/nitrative stress and subsequent dysfunction in the heart

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

The accelerated post-infarction progression of cardiac remodelling is associated with genetic changes in an untreated streptozotocin-induced diabetic rat model

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Comparative effects of statins on murine cardiac gene expression profiles in normal mice.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Transcriptional profiling for understanding the basis of mitochondrial involvement in disease and toxicity using the mitochondria-specific MitoChip.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Ribosome profiling: new views of translation, from single codons to genome scale

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Targeted Ablation of Periostin-Expressing Activated Fibroblasts Prevents Adverse Cardiac Remodeling in Mice.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVX070

21 January 2018

Gene network analysis: from heart development to cardiac therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5437366

30 October 2018

MicroRNAs associated with ischemia-reperfusion injury and cardioprotection by ischemic pre- and postconditioning: protectomiRs

1 reference

https://pubmed.ncbi.nlm.nih.gov/28460026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/28460026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/28460026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

State-of-the-art on non-coding RNA bioinformatics, diagnostics and therapeutics in cardiovascular diseases: Preface to SI Non-coding RNAs in cardiovascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/28460026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered microRNA expression associated with reduced catecholamine sensitivity in patients with chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/28460026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic modifier loci affecting survival and cardiac function in murine dilated cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/28460026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/CVR/CVX070

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28460026%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28460026%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28460026%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

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