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A node between proliferation, apoptosis, and growth arrest
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scholarly article
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Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
review article
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Europe PubMed Central
title
A node between proliferation, apoptosis, and growth arrest
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
author
Mikhail Blagosklonny
series ordinal
1
object named as
Blagosklonny MV
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stated in
Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
language of work or name
English
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publication date
1 August 1999
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Europe PubMed Central
PubMed ID
10440867
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28 July 2017
published in
BioEssays
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stated in
Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
volume
21
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stated in
Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
page(s)
704-709
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Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
issue
8
1 reference
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Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
cites work
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Oncogenes and the strategy of growth factors
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Oncoprotein networks
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Induction of apoptosis in fibroblasts by c-myc protein
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Biological response to phorbol ester determined by alternative G1 pathways
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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation
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Cooperating oncogenes converge to regulate cyclin/cdk complexes.
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Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition
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High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.
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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.
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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
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E1A signaling to p53 involves the p19(ARF) tumor suppressor
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Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
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21 January 2018
p53 and E2F-1 cooperate to mediate apoptosis
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21 January 2018
Distinct roles for E2F proteins in cell growth control and apoptosis
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The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins
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The retinoblastoma protein and cell cycle control
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Caspases: enemies within
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Regulation of cell death protease caspase-9 by phosphorylation
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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.
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21 January 2018
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21 January 2018
Bcl-2 targets the protein kinase Raf-1 to mitochondria
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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
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21 January 2018
Binding and modulation of p53 by p300/CBP coactivators
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21 January 2018
Recruitment of p300/CBP in p53-dependent signal pathways
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21 January 2018
Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function
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21 January 2018
An essential role for p300/CBP in the cellular response to hypoxia
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21 January 2018
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
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21 January 2018
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein
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21 January 2018
p14ARF links the tumour suppressors RB and p53.
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21 January 2018
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.
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21 January 2018
WAF1, a potential mediator of p53 tumor suppression
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21 January 2018
Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.
1 reference
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Crossref
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21 January 2018
Regulation of c-myc expression by Ras/Raf signalling
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Crossref
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21 January 2018
Growth factor modulation of p53-mediated growth arrest versus apoptosis
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21 January 2018
Senescence of human fibroblasts induced by oncogenic Raf.
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21 January 2018
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
1 reference
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21 January 2018
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
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retrieved
21 January 2018
Signal transduction via serine/threonine kinase receptors
1 reference
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Crossref
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21 January 2018
The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.
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21 January 2018
p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells
1 reference
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21 January 2018
E2F and cell proliferation: a world turned upside down
1 reference
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21 January 2018
Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
p21-containing cyclin kinases exist in both active and inactive states
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2F%28SICI%291521-1878%28199908%2921%3A8%3C704%3A%3AAID-BIES10%3E3.0.CO%3B2-5
retrieved
21 January 2018
Identifiers
DOI
10.1002/(SICI)1521-1878(199908)21:8<704::AID-BIES10>3.0.CO;2-5
1 reference
stated in
Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
PubMed ID
10440867
1 reference
stated in
Europe PubMed Central
PubMed ID
10440867
retrieved
28 July 2017
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