(Q33709285)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

review article

1 reference

title

The conformational switch in 7-transmembrane receptors: the muscarinic receptor paradigm (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

main subject

transmembrane protein

0 references

author

Zhi-Liang Lu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

author name string

E C Hulme

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

S D Ward

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

K Allman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

C A Curtis

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

language of work or name

English

0 references

publication date

1 June 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Pharmacology

11 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

volume

375

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

issue

1-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

page(s)

247-260

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

Light-induced exposure of the cytoplasmic end of transmembrane helix seven in rhodopsin

11 December 2019

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Certain activating mutations within helix 6 of the human luteinizing hormone receptor may be explained by alterations that allow transmembrane regions to activate Gs.

7 January 2021

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Transducin-alpha C-terminal peptide binding site consists of C-D and E-F loops of rhodopsin

7 January 2021

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Analysis of zinc binding sites in protein crystal structures

7 January 2021

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Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study

7 January 2021

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7 January 2021

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7 January 2021

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The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor

7 January 2021

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Neurobiology of the Caenorhabditis elegans genome.

7 January 2021

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Biochemical studies on muscarinic acetylcholine receptors

7 January 2021

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Mapping of single amino acid residues required for selective activation of Gq/11 by the m3 muscarinic acetylcholine receptor

7 January 2021

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How receptors talk to trimeric G proteins

7 January 2021

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Amino acid side chains that define muscarinic receptor/G-protein coupling. Studies of the third intracellular loop

7 January 2021

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Structure/function relationships of a G-protein coupling pocket formed by the third intracellular loop of the m5 muscarinic receptor

7 January 2021

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The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling

7 January 2021

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Mechanism of activation and inactivation of opsin: role of Glu113 and Lys296

7 January 2021

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A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotropin-releasing hormone receptor in an inactive conformation.

7 January 2021

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Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state

7 January 2021

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Conformational changes in rhodopsin. Movement of helix f detected by site-specific chemical labeling and fluorescence spectroscopy

7 January 2021

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Lipid patches in membrane protein oligomers: crystal structure of the bacteriorhodopsin-lipid complex

7 January 2021

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Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.

7 January 2021

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Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

7 January 2021

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The opsin family of proteins

7 January 2021

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G protein-coupled receptors. II. Mechanism of agonist activation

7 January 2021

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Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

7 January 2021

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Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

7 January 2021

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Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6.

7 January 2021

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Combined biophysical and biochemical information confirms arrangement of transmembrane helices visible from the three-dimensional map of frog rhodopsin

7 January 2021

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Structure of a G-protein-coupling domain of a muscarinic receptor predicted by random saturation mutagenesis

7 January 2021

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GPCRDB: an information system for G protein-coupled receptors

7 January 2021

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Scanning mutagenesis of transmembrane domain 3 of the M1 muscarinic acetylcholine receptor

7 January 2021

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Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled

7 January 2021

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Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment

7 January 2021

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G protein-coupled receptors. I. Diversity of receptor-ligand interactions

7 January 2021

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Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin

7 January 2021

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Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state

7 January 2021

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Efficient Interaction with a Receptor Requires a Specific Type of Prenyl Group on the G Protein γ Subunit

7 January 2021

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Examination of ligand-induced conformational changes in the beta 2-adrenergic receptor by fluorescence spectroscopy.

7 January 2021

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Molecular basis of receptor/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits

7 January 2021

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Characterisation of an improved two-dimensional p22121 crystal from bovine rhodopsin.

7 January 2021

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Up-regulation of the levels of expression and function of a constitutively active mutant of the hamster alpha1B-adrenoceptor by ligands that act as inverse agonists

7 January 2021

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Agonist-independent regulation of constitutively active G-protein-coupled receptors

7 January 2021

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The functional topography of transmembrane domain 3 of the M1 muscarinic acetylcholine receptor, revealed by scanning mutagenesis.

7 January 2021

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The role of the aspartate-arginine-tyrosine triad in the m1 muscarinic receptor: mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling

7 January 2021

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Rhodopsin-family receptors associate with small G proteins to activate phospholipase D.

7 January 2021

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

7 January 2021

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Folding funnels and frustration in off-lattice minimalist protein landscapes

7 January 2021

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Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin

7 January 2021

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Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor

7 January 2021

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The transmembrane 7-alpha-bundle of rhodopsin: distance geometry calculations with hydrogen bonding constraints

7 January 2021

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Opioid receptor three-dimensional structures from distance geometry calculations with hydrogen bonding constraints

7 January 2021

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Na+ ions binding to the bradykinin B2 receptor suppress agonist-independent receptor activation

7 January 2021

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Activating mutations of rhodopsin and other G protein-coupled receptors

7 January 2021

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In vivo assembly of rhodopsin from expressed polypeptide fragments

7 January 2021

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The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate

7 January 2021

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Locating ligand-binding sites in 7TM receptors by protein engineering.

7 January 2021

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Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

7 January 2021

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The steric trigger in rhodopsin activation

7 January 2021

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Crystal structure of a G-protein beta gamma dimer at 2.1A resolution

7 January 2021

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Constitutive activation of the m5 muscarinic receptor by a series of mutations at the extracellular end of transmembrane 6.

7 January 2021

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Identification of a ligand-dependent switch within a muscarinic receptor

7 January 2021

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Arrangement of rhodopsin transmembrane α-helices

7 January 2021

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Molecular Architecture of G Protein-Coupled Receptors.

7 January 2021

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Molecular basis of muscarinic acetylcholine receptor function

7 January 2021

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Molecular biology of muscarinic acetylcholine receptors

7 January 2021

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Molecular basis of receptor/G-protein-coupling selectivity

7 January 2021

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Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor

7 January 2021

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The First and Second Cytoplasmic Loops of the G-Protein Receptor, Rhodopsin, Independently Form β-Turns†

7 January 2021

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10.1016/S0014-2999(99)00297-6

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10443581%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1 reference