(Q33711156)

28 July 2017

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title

T cell signaling: a decision of life and death (English)

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28 July 2017

Medema JP

1

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28 July 2017

Borst J

series ordinal

2

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28 July 2017

language of work or name

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1 May 1999

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28 July 2017

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28 July 2017

volume

60

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28 July 2017

issue

5

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28 July 2017

page(s)

403-411

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Antigen receptors on T and B lymphocytes: parallels in organization and function

28 July 2017

cites work

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7 January 2021

T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases

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7 January 2021

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

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7 January 2021

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

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7 January 2021

Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

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7 January 2021

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes

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7 January 2021

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

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7 January 2021

The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

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7 January 2021

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

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7 January 2021

T cell antigen receptor signal transduction pathways

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7 January 2021

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

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7 January 2021

Activators and effectors of ras p21 proteins

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7 January 2021

Transcriptional regulation by MAP kinases

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7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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7 January 2021

Inositol trisphosphate and calcium signalling

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7 January 2021

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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7 January 2021

Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity

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7 January 2021

T-cell antigen receptor-induced signal-transduction pathways--activation and function of protein kinases C in T lymphocytes

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7 January 2021

Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation

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7 January 2021

Stimulation of p21 ras upon T-cell activation

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7 January 2021

p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells

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7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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7 January 2021

Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation

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7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

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7 January 2021

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

1 reference

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7 January 2021

A tyrosine-phosphorylated 110-120-kDa protein associates with the C-terminal SH2 domain of phosphotyrosine phosphatase-1D in T cell receptor-stimulated T cells

1 reference

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7 January 2021

A target for phosphoinositide 3-kinase: Akt/PKB.

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7 January 2021

T cell receptor antagonists and partial agonists

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7 January 2021

The complexities of T-cell co-stimulation: CD28 and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

CD28/B7 system of T cell costimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Activation of src family kinase lck following CD28 crosslinking in the Jurkat leukemic cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras

1 reference

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7 January 2021

The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras

1 reference

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7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Networking Rho family GTPases in lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Nuclear appearance of a factor that binds the CD28 response element within the interleukin-2 enhancer correlates with interleukin-2 production

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites

1 reference

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7 January 2021

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

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7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

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7 January 2021

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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7 January 2021

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7 January 2021

The role of phosphotyrosine phosphatases in haematopoietic cell signal transduction

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7 January 2021

The Cbl family of signal transduction molecules

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7 January 2021

The emerging field of receptor-mediated inhibitory signaling: SHP or SHIP?

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7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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7 January 2021

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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7 January 2021

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

1 reference

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7 January 2021

Receptor-stimulated death pathway is opened by antigen in mature T cells

1 reference

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7 January 2021

Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide

1 reference

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7 January 2021

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1 reference

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7 January 2021

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

1 reference

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7 January 2021

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

ICE family proteases: mediators of all apoptotic cell death?

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

FLICE Induced Apoptosis in a Cell-free System

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Mitochondrial control of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

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7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Functions of ceramide in coordinating cellular responses to stress

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

CD95/Fas-induced ceramide formation proceeds with slow kinetics and is not blocked by caspase-3/CPP32 inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Caspase-dependent ceramide production in Fas- and HLA class I-mediated peripheral T cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Activation interferes with the APO-1 pathway in mature human T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Resistance of cultured peripheral T cells towards activation-induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death-inducing signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Does the Caenorhabditis elegans protein CED-4 contain a region of homology to the mammalian death effector domain?

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

Placing death under control

1 reference

https://api.crossref.org/works/10.1016%2FS0198-8859%2899%2900008-7

7 January 2021

10.1016/S0198-8859(99)00008-7

Identifiers

DOI

1 reference

28 July 2017

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