(Q33713783)

English

c-Jun N-terminal kinase contributes to aberrant retinoid signaling in lung cancer cells by phosphorylating and inducing proteasomal degradation of retinoic acid receptor alpha

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 July 2017

c-Jun N-terminal kinase contributes to aberrant retinoid signaling in lung cancer cells by phosphorylating and inducing proteasomal degradation of retinoic acid receptor alpha (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

phosphorylation

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1 reference

based on heuristic

inferred from title

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author name string

Harish Srinivas

1

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PubMed publication ID

28 July 2017

Denise M Juroske

2

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28 July 2017

Shailaja Kalyankrishna

3

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28 July 2017

Dianna D Cody

4

1 reference

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28 July 2017

Roger E Price

5

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28 July 2017

Xiao-Chun Xu

6

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28 July 2017

Ramesh Narayanan

7

1 reference

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28 July 2017

Nancy L Weigel

8

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28 July 2017

Jonathan M Kurie

9

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28 July 2017

language of work or name

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publication date

1 February 2005

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28 July 2017

Molecular and Cellular Biology

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28 July 2017

25

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Europe PubMed Central

PubMed publication ID

28 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1054-1069

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells

1 reference

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Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint

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UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair

1 reference

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21 June 2018

Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RAR gamma degradation and transactivation

1 reference

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

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Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

1 reference

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21 June 2018

Importance of the regulation of nuclear receptor degradation

1 reference

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21 June 2018

Ligand-dependent degradation of retinoid X receptors does not require transcriptional activity or coactivator interactions

1 reference

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21 June 2018

Binding of ligands and activation of transcription by nuclear receptors.

1 reference

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

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21 June 2018

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

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21 June 2018

Increased retinoic acid responsiveness in lung carcinoma cells that are nonresponsive despite the presence of endogenous retinoic acid receptor (RAR) beta by expression of exogenous retinoid receptors retinoid X receptor alpha, RAR alpha, and RAR ga

1 reference

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21 June 2018

Identification of a phosphorylation site in the hinge region of the human progesterone receptor and additional amino-terminal phosphorylation sites

1 reference

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21 June 2018

Regulation of somatic growth by the p160 coactivator p/CIP

1 reference

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21 June 2018

Signal transduction by the JNK group of MAP kinases

1 reference

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21 June 2018

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

1 reference

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21 June 2018

Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation

1 reference

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21 June 2018

Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

The Hallmarks of Cancer

1 reference

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21 June 2018

Orphan receptor COUP-TF is required for induction of retinoic acid receptor beta, growth inhibition, and apoptosis by retinoic acid in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Mitogen-activated protein kinase inhibits 1,25-dihydroxyvitamin D3-dependent signal transduction by phosphorylating human retinoid X receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Nuclear receptor coregulators: cellular and molecular biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Substrate targeting in the ubiquitin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Retinoic acid-mediated growth inhibition of small cell lung cancer cells is associated with reduced myc and increased p27Kip1 expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gamma1 and negatively regulates its transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Activity of anti-erbB-2 recombinant toxin OLX-209 on lung cancer cell lines in the absence of erbB-2 gene amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

The ubiquitin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

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Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Sounding the alarm: protein kinase cascades activated by stress and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Receptor-selective retinoid agonists and teratogenic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

The RXR heterodimers and orphan receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

The nuclear receptor superfamily: the second decade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Human lung cancer cell lines exhibit resistance to retinoic acid treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Phosphorylation enhances the target gene sequence-dependent dimerization of thyroid hormone receptor with retinoid X receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Ligand-dependent occupancy of the retinoic acid receptor beta 2 promoter in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia and coexpression precedes squamous cell carcinoma development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Evidence for impaired retinoic acid receptor-thyroid hormone receptor AF-2 cofactor activity in human lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

The regulation of AP-1 activity by mitogen-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Regulation of insulin-like growth factor 1 binding protein 3 levels by epidermal growth factor and retinoic acid in cervical epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

1 reference

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21 June 2018

Phosphorylation of the retinoic acid receptor-alpha by protein kinase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

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21 June 2018

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

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21 June 2018

Transcription activation by the adenovirus E1a protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

21 June 2018

In vivo respiratory-gated micro-CT imaging in small-animal oncology models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

30 October 2018

Retinoic acid receptors beta and gamma do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

30 October 2018

Loss of retinoic acid receptor beta gene expression is linked to aberrant histone H3 acetylation in lung cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

30 October 2018

Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

30 October 2018

Ultraviolet irradiation of human skin causes functional vitamin A deficiency, preventable by all-trans retinoic acid pre-treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

30 October 2018

Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

30 October 2018

Inhibition of epidermal growth factor-like growth factor secretion in tracheobronchial epithelial cells by vitamin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

30 October 2018

A specific defect in the retinoic acid response associated with human lung cancer cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543999

30 October 2018

Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

All-trans-retinoic acid inhibits Jun N-terminal kinase-dependent signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation of the retinoid X receptor alpha by activated c-Jun NH2-terminal kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promoter Methylation and Silencing of the Retinoic Acid Receptor- Gene in Lung Carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress pathway activation induces phosphorylation of retinoid X receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimerization with retinoid X receptors and phosphorylation modulate the retinoic acid-induced degradation of retinoic acid receptors alpha and gamma through the ubiquitin-proteasome pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of oncogenic K-ras signaling by aerosolized gene delivery in a mouse model of human lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that phosphatidylinositol 3-kinase- and mitogen-activated protein kinase kinase-4/c-Jun NH2-terminal kinase-dependent Pathways cooperate to maintain lung cancer cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High frequency of retinoic acid receptor beta abnormalities in human lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15657432

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.25.3.1054-1069.2005

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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