(Q33714950)

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Genetic modulation of the interleukin 6 (IL-6) system in patients with advanced gastric cancer: a background for an alternative target therapy.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Genetic modulation of the interleukin 6 (IL-6) system in patients with advanced gastric cancer: a background for an alternative target therapy (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Annamaria Ruzzo

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Elisa Giacomini

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Daniele Santini

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Giuseppe Tonini

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Vincenzo Catalano

2

object named as

Vincenzo Catalano

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Emanuele Canestrari

3

object named as

Emanuele Canestrari

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Giammaria Fiorentini

8

object named as

Giammaria Fiorentini

1 reference

Europe PubMed Central

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19 March 2020

9

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Mauro Magnani

1 reference

Europe PubMed Central

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19 March 2020

author name string

Francesco Graziano

10

1 reference

Europe PubMed Central

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19 March 2020

language of work or name

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publication date

22 May 2014

1 reference

Europe PubMed Central

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19 March 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

357

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

A phase I, open-label study of siltuximab, an anti-IL-6 monoclonal antibody, in patients with B-cell non-Hodgkin lymphoma, multiple myeloma, or Castleman disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Cytokine patterns in patients with cancer: a systematic review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

IL-6 polymorphisms: a useful genetic tool for inflammation research?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

The multifaceted role of the microenvironment in liver metastasis: biology and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Cancer cachexia: mediators, signaling, and metabolic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Interleukin-6 signaling pathway in targeted therapy for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Targeting the interleukin-6/Jak/stat pathway in human malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Hitting a complex target: an update on interleukin-6 trans-signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

An intermediate-risk multiple myeloma subgroup is defined by sIL-6r: levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

A humanized anti-IL-6 antibody (ALD518) in non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

The pro- and anti-inflammatory properties of the cytokine interleukin-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Clinical significances of preoperative serum interleukin-6 and C-reactive protein level in operable gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Host genetic variants in the interleukin-6 promoter predict poor outcome in patients with estrogen receptor-positive, node-positive breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Second-line chemotherapy for patients with advanced gastric cancer: who may benefit?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

sIL-6R: more than an agonist?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

IL-6 induces AGS gastric cancer cell invasion via activation of the c-Src/RhoA/ROCK signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

28 July 2018

Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Interleukin-6 increases vascular endothelial growth factor and angiogenesis in gastric carcinoma

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Correlation between serum levels of interleukin-6 and vascular endothelial growth factor in gastric carcinoma.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Elevated levels of circulating platelet microparticles, VEGF, IL-6 and RANTES in patients with gastric cancer: possible role of a metastasis predictor.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Cytokine and cytokine receptor gene polymorphisms and their functionality.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Metastatic cells can escape the proapoptotic effects of TNF-α through increased autocrine IL-6/STAT3 signaling

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Polymorphism in cytokine genes as prognostic markers in Hodgkin's lymphoma.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Serum interleukin-6 level but not genotype predicts survival after resection in stages II and III gastric carcinoma.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Vorinostat in advanced prostate cancer patients progressing on prior chemotherapy (National Cancer Institute Trial 6862): trial results and interleukin-6 analysis: a study by the Department of Defense Prostate Cancer Clinical Trial Consortium [...]

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Possible role for tocilizumab, an anti-interleukin-6 receptor antibody, in treating cancer cachexia

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Favorable responses to tocilizumab in two patients with cancer-related cachexia

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

A phase 1 study of a chimeric monoclonal antibody against interleukin-6, siltuximab, combined with docetaxel in patients with metastatic castration-resistant prostate cancer.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-14-357

21 January 2018

Interleukin-6 -174G-->C polymorphism is associated with improved outcome in high-risk breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046495

30 October 2018

An interleukin-6 gene promoter polymorphism influences the biological phenotype of ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24886605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of interleukin-6 (IL-6) in the spread of gastric cancer: role of IL-6 as a prognostic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24886605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24886605

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2407-14-357

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Dimensions Publication ID

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24886605%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

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