(Q33715944)

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Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade (English)

1 reference

Europe PubMed Central

28 July 2017

1 reference

based on heuristic

inferred from title

Eleftherios P. Diamandis

4

object named as

Eleftherios P Diamandis

1 reference

Europe PubMed Central

28 July 2017

author name string

Azza Eissa

1

1 reference

Europe PubMed Central

28 July 2017

Vanessa Amodeo

2

1 reference

Europe PubMed Central

28 July 2017

Christopher R Smith

3

1 reference

Europe PubMed Central

28 July 2017

language of work or name

0 references

publication date

12 October 2010

1 reference

Europe PubMed Central

28 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

28 July 2017

286

1 reference

Europe PubMed Central

28 July 2017

1

1 reference

Europe PubMed Central

28 July 2017

687-706

1 reference

Europe PubMed Central

28 July 2017

Isolation of SPINK6 in human skin: selective inhibitor of kallikrein-related peptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Analyzing the protease web in skin: meprin metalloproteases are activated specifically by KLK4, 5 and 8 vice versa leading to processing of proKLK7 thereby triggering its activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Keratinocytes synthesize enteropeptidase and multiple forms of trypsinogen during terminal differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

SPINK9: a selective, skin-specific Kazal-type serine protease inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade. Possible function in seminal plasma and skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Kallikrein 8 is involved in skin desquamation in cooperation with other kallikreins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Inhibition profiles of human tissue kallikreins by serine protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Kallikrein-related peptidase 14 may be a major contributor to trypsin-like proteolytic activity in human stratum corneum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Activation and enzymatic characterization of recombinant human kallikrein 8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Corneodesmosomal cadherins are preferential targets of stratum corneum trypsin- and chymotrypsin-like hyperactivity in Netherton syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

The cornified envelope: a model of cell death in the skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Consequences of C-terminal domains and N-terminal signal peptide deletions on LEKTI secretion, stability, and subcellular distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

A proteolytic cascade of kallikreins in the stratum corneum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Epidermal desquamation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

The emerging roles of human tissue kallikreins in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Epidermal lamellar granules transport different cargoes as distinct aggregates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Expression of LEKTI domains 6-9' in the baculovirus expression system: recombinant LEKTI domains 6-9' inhibit trypsin and subtilisin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Analysis of proteins with caseinolytic activity in a human stratum corneum extract revealed a yet unidentified cysteine protease and identified the so-called "stratum corneum thiol protease" as cathepsin l2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Biology and clinical relevance of naturally occurring antimicrobial peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Epidermal expression of serine protease, neuropsin (KLK8) in normal and pathological skin samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Elevated stratum corneum hydrolytic activity in Netherton syndrome suggests an inhibitory regulation of desquamation by SPINK5-derived peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

The new human tissue kallikrein gene family: structure, function, and association to disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

The expanded human kallikrein gene family: locus characterization and molecular cloning of a new member, KLK-L3 (KLK9).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Effect of 12-O-tetradecanoyl-phorbol ester and incisional wounding on neuropsin mRNA and its protein expression in murine skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Sequence analysis and expression of human neuropsin cDNA and gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Kindling induces neuropsin mRNA in the mouse brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Evidence for a role of corneodesmosin, a protein which may serve to modify desmosomes during cornification, in stratum corneum cell cohesion and desquamation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Human eccrine sweat contains tissue kallikrein and kininase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Ultrastructural localization of calcium in psoriatic and normal human epidermis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Stratum corneum chymotryptic enzyme: a proteinase which may be generally present in the stratum corneum and with a possible involvement in desquamation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

14 July 2018

Activation profiles and regulatory cascades of the human kallikrein-related peptidases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Expression of neuropsin in the keratinizing epithelial tissue-immunohistochemical analysis of wild-type and nude mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Prolonged recovery of ultraviolet B-irradiated skin in neuropsin (KLK8)-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Purification and characterization of human kallikrein 11, a candidate prostate and ovarian cancer biomarker, from seminal plasma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Quantification of human tissue kallikreins in the stratum corneum: dependence on age and gender

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Some magnesium salts and a mixture of magnesium and calcium salts accelerate skin barrier recovery.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Development of an anodic stripping voltammetric assay, using a disposable mercury-free screen-printed carbon electrode, for the determination of zinc in human sweat

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Calcium regulation of cell-cell contact and differentiation of epidermal cells in culture *1An ultrastructural study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Elevated Human Tissue Kallikrein Levels in the Stratum Corneum and Serum of Peeling Skin Syndrome-Type B Patients Suggests an Over-desquamation of Corneocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.125310

21 January 2018

Quantification of Eight Tissue Kallikreins in the Stratum Corneum and Sweat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

30 October 2018

The New Human Tissue Kallikrein Gene Family: Structure, Function, and Association to Disease1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013028

30 October 2018

Histochemical and histofluorescence tracing of chelatable zinc in the developing mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20940292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic degradation of desmosomes in plantar stratum corneum leads to cell dissociation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20940292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A chymotrypsin-like proteinase that may be involved in desquamation in plantar stratum corneum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20940292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrity of the permeability barrier is crucial for maintenance of the epidermal calcium gradient

1 reference

https://pubmed.ncbi.nlm.nih.gov/20940292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.125310

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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