(Q33717763)

28 July 2017

title

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE. (English)

1 reference

28 July 2017

Gergely Talaber

3

0 references

Dmitry M. Chudakov

Dmitriy M Chudakov

10

0 references

Andras Perl

Andras Perl

14

0 references

Walter Malorni

Walter Malorni

11

0 references

Frank A Middleton

12

Frank Middleton

1 reference

28 July 2017

Tiffany N Caza

1

1 reference

28 July 2017

David R Fernandez

2

1 reference

28 July 2017

Zachary Oaks

4

1 reference

28 July 2017

Mark Haas

5

1 reference

28 July 2017

Michael P Madaio

6

1 reference

28 July 2017

Zhi-Wei Lai

7

1 reference

28 July 2017

Gabriella Miklossy

8

1 reference

28 July 2017

Ram R Singh

9

1 reference

28 July 2017

Katalin Banki

13

1 reference

28 July 2017

language of work or name

English

0 references

publication date

29 July 2013

1 reference

Annals of the Rheumatic Diseases

28 July 2017

published in

1 reference

28 July 2017

volume

73

1 reference

28 July 2017

issue

10

1 reference

28 July 2017

page(s)

1888-1897

1 reference

Murine lupus susceptibility locus Sle1c2 mediates CD4+ T cell activation and maps to estrogen-related receptor γ.

28 July 2017

cites work

1 reference

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N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial

21 June 2018

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Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity

21 June 2018

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Biogenesis and cargo selectivity of autophagosomes

21 June 2018

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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

21 June 2018

1 reference

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The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

21 June 2018

1 reference

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The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse

21 June 2018

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Regulatory T cells require mammalian target of rapamycin signaling to maintain both homeostasis and alloantigen-driven proliferation in lymphocyte-replete mice

21 June 2018

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21 June 2018

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Macroautophagy regulates energy metabolism during effector T cell activation

21 June 2018

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Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

21 June 2018

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Trafficking and signaling in mammalian autophagy

21 June 2018

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21 June 2018

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Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment.

21 June 2018

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D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling

21 June 2018

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Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

21 June 2018

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Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation

21 June 2018

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The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 June 2018

1 reference

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 June 2018

1 reference

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Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus

21 June 2018

1 reference

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Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS)

21 June 2018

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Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells

21 June 2018

1 reference

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Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity

21 June 2018

1 reference

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T Cell Activation-Induced Mitochondrial Hyperpolarization Is Mediated by Ca2+- and Redox-Dependent Production of Nitric Oxide

21 June 2018

1 reference

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Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4047212

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

21 June 2018

1 reference

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Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus

21 June 2018

1 reference

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Genetics of systemic autoimmunity in mouse models of lupus

21 June 2018

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Lupus susceptibility genes on human chromosome 1.

21 June 2018

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Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand

21 June 2018

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Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

21 June 2018

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The 1982 revised criteria for the classification of systemic lupus erythematosus

21 June 2018

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Fc epsilon receptor type I gamma chain replaces the deficient T cell receptor zeta chain in T cells of patients with systemic lupus erythematosus

21 June 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2013-203794

Regulation of CD4 expression via recycling by HRES-1/RAB4 controls susceptibility to HIV infection

21 January 2018

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Geranylgeranyl transferase type II inhibition prevents myeloma bone disease.

21 January 2018

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Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

21 January 2018

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IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis

21 January 2018

1 reference

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Effector activity of OKT4+ and OKT8+ T-cell subsets in lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells

21 January 2018

1 reference

12 December 2020

Rapamycin prolongs survival and arrests pathophysiologic changes in murine systemic lupus erythematosus

1 reference

12 December 2020

Polymorphic genotypes of the HRES-1 human endogenous retrovirus locus correlate with systemic lupus erythematosus and autoreactivity

1 reference

12 December 2020

Haplotypes of the HRES-1 endogenous retrovirus are associated with development and disease manifestations of systemic lupus erythematosus

1 reference

12 December 2020

10.1136/ANNRHEUMDIS-2013-203794

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference