(Q33721211)

28 July 2017

title

DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancer (English)

1 reference

28 July 2017

main subject

protein ubiquitination

1 reference

7

S Bae

1 reference

28 July 2017

Y M Choi

1

1 reference

28 July 2017

K B Kim

2

1 reference

28 July 2017

J H Lee

3

1 reference

28 July 2017

Y K Chun

4

1 reference

28 July 2017

I S An

5

1 reference

28 July 2017

S An

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

12 December 2016

1 reference

28 July 2017

1 reference

28 July 2017

volume

36

1 reference

28 July 2017

issue

20

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28 July 2017

page(s)

2802-2812

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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International

28 July 2017

copyright license

start time

12 December 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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The Msi Family of RNA-Binding Proteins Function Redundantly as Intestinal Oncoproteins

21 June 2018

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Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin

21 June 2018

1 reference

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Musashi-2 promotes hepatitis Bvirus related hepatocellular carcinoma progression via the Wnt/β-catenin pathway.

21 June 2018

1 reference

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Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.

21 June 2018

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Relationship between promoter methylation & tissue expression of MGMT gene in ovarian cancer

21 June 2018

1 reference

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Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

21 June 2018

1 reference

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Hsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complex

21 June 2018

1 reference

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Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition.

21 June 2018

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Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Downregulated RhoBTB2 expression contributes to poor outcome in osteosarcoma patients

21 June 2018

1 reference

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The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells

21 June 2018

1 reference

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Decreased expression of the DBC2 gene and its clinicopathological significance in breast cancer: correlation with aberrant DNA methylation

21 June 2018

1 reference

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Prognostic significance of expression levels of stem cell regulators MSI2 and NUMB in acute myeloid leukemia

21 June 2018

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Epigenetic regulation of cancer stem cell genes in triple-negative breast cancer.

21 June 2018

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Akt is negatively regulated by the MULAN E3 ligase

21 June 2018

1 reference

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RhoBTB2 (DBC2) functions as tumor suppressor via inhibiting proliferation, preventing colony formation and inducing apoptosis in breast cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

E3 ubiquitin ligase Hades negatively regulates the exonuclear function of p53.

21 June 2018

1 reference

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Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets

21 June 2018

1 reference

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Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

21 June 2018

1 reference

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The RNA binding protein Musashi1 regulates apoptosis, gene expression and stress granule formation in urothelial carcinoma cells

21 June 2018

1 reference

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The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis

21 June 2018

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A novel tumor suppressor gene RhoBTB2 (DBC2): frequent loss of expression in sporadic breast cancer

21 June 2018

1 reference

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Exploring the linkage dependence of polyubiquitin conformations using molecular modeling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Genome-wide screening and identification of novel proteolytic cleavage targets of caspase-8 and -10 in vitro

21 June 2018

1 reference

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Mutation analysis of the 8p candidate tumour suppressor genes DBC2 (RHOBTB2) and LZTS1 in bladder cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Regulation of apoptosis proteins in cancer cells by ubiquitin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Protein degradation: CUL-3 and BTB--partners in proteolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

DBC2, a candidate for a tumor suppressor gene involved in breast cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

Genetic analysis of the DBC2 gene in gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

DBC2 gene is silenced by promoter methylation in bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

Evaluation of protein expression and DNA methylation profiles detected by pyrosequencing in invasive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

Downregulation of Msi1 suppresses the growth of human colon cancer by targeting p21cip1.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

A novel gene, MSI2, encoding a putative RNA-binding protein is recurrently rearranged at disease progression of chronic myeloid leukemia and forms a fusion gene with HOXA9 as a result of the cryptic t(7;17)(p15;q23).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5442418

BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

RhoBTB2 (DBC2) comes of age as a multifunctional tumor suppressor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

RhoBTB2 gene in breast cancer is silenced by promoter methylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

MSI2 protein expression predicts unfavorable outcome in acute myeloid leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.441

Loss of DBC2 expression is an early and progressive event in the development of lung adenocarcinoma

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27941885

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2016.441

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference