(Q33722735)

28 July 2017

title

Plasminogen activator inhibitor-1 (PAI-1) is cardioprotective in mice by maintaining microvascular integrity and cardiac architecture (English)

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28 July 2017

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3

Victoria A Ploplis

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28 July 2017

2

Francis J Castellino

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28 July 2017

Zhi Xu

1

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28 July 2017

language of work or name

English

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publication date

15 December 2009

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28 July 2017

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28 July 2017

volume

115

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28 July 2017

issue

10

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28 July 2017

page(s)

2038-2047

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Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling

28 July 2017

cites work

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21 June 2018

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21 June 2018

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Severe deficiency of coagulation Factor VII results in spontaneous cardiac fibrosis in mice

21 June 2018

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Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain.

21 June 2018

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Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice

21 June 2018

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A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X

21 June 2018

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Plasminogen activator inhibitor-1 and restenosis

21 June 2018

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Targeting plasminogen activator inhibitor-1: role in cell signaling and the biology of domain-specific knock-in mice

21 June 2018

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A urokinase-type plasminogen activator deficiency diminishes the frequency of intestinal adenomas in ApcMin/+ mice

21 June 2018

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TGF-beta signaling in vascular fibrosis.

21 June 2018

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Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ

21 June 2018

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Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation

21 June 2018

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Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling.

21 June 2018

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Increased expression of plasminogen activator inhibitor-1 in cardiomyocytes contributes to cardiac fibrosis after myocardial infarction.

21 June 2018

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Decreased mortality of ischaemic heart disease among carriers of haemophilia

21 June 2018

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A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritis

21 June 2018

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Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1.

21 June 2018

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Myeloperoxidase and plasminogen activator inhibitor 1 play a central role in ventricular remodeling after myocardial infarction

21 June 2018

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Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction

21 June 2018

1 reference

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Human plasminogen activator inhibitor-1 (PAI-1) deficiency: characterization of a large kindred with a null mutation in the PAI-1 gene

21 June 2018

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TGF-beta latency: biological significance and mechanisms of activation

21 June 2018

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Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene

21 June 2018

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Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization

21 June 2018

1 reference

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Hypertrophic cardiomyopathy. Interrelations of clinical manifestations, pathophysiology, and therapy (1).

21 June 2018

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A profibrotic effect of plasminogen activator inhibitor type-1 (PAI-1) in the heart

21 June 2018

1 reference

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The development of cardiac fibrosis in low tissue factor mice is gender-dependent and is associated with differential regulation of urokinase plasminogen activator.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837335

Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNK-mediated pathway.

30 October 2018

1 reference

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Mechanisms of cardiac fibrosis induced by urokinase plasminogen activator.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837335

A fibrinogen deficiency accelerates the initiation of LDL cholesterol-driven atherosclerosis via thrombin generation and platelet activation in genetically predisposed mice

30 October 2018

1 reference

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Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardio

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837335

Pericytes influence endothelial cell growth characteristics: role of plasminogen activator inhibitor type 1 (PAI-1).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837335

Conservation of critical functional domains in murine plasminogen activator inhibitor-1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837335

Enhanced in vitro proliferation of aortic endothelial cells from plasminogen activator inhibitor-1-deficient mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837335

Impact of anesthesia on cardiac function during echocardiography in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837335

Plasminogen activator inhibitor-1 deficiency prevents hypertension and vascular fibrosis in response to long-term nitric oxide synthase inhibition

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837335

Raised blood pressure, not renin–angiotensin systems, causes cardiac fibrosis in TGR m(Ren2)27 rats

30 October 2018

1 reference

12 December 2020

Overexpression of urokinase by macrophages or deficiency of plasminogen activator inhibitor type 1 causes cardiac fibrosis in mice

1 reference

12 December 2020

Post-transcriptional regulation of extracellular matrix metalloproteinase in human heart end-stage failure secondary to ischemic cardiomyopathy

1 reference

12 December 2020

A balance between tissue factor and tissue factor pathway inhibitor is required for embryonic development and hemostasis in adult mice

1 reference

12 December 2020

A coagulation factor VII deficiency protects against acute inflammatory responses in mice

1 reference

12 December 2020

10.1182/BLOOD-2009-09-244962

Identifiers

DOI

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28 July 2017

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28 July 2017

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