(Q33728360)

28 July 2017

title

HP1α mediates defective heterochromatin repair and accelerates senescence in Zmpste24-deficient cells (English)

1 reference

28 July 2017

Jia Liu

1

1 reference

28 July 2017

Xianhui Yin

2

1 reference

28 July 2017

Baohua Liu

3

1 reference

28 July 2017

Huiling Zheng

4

1 reference

28 July 2017

Guangqian Zhou

5

1 reference

28 July 2017

Liyun Gong

6

1 reference

28 July 2017

Meng Li

7

1 reference

28 July 2017

Xueqin Li

8

1 reference

28 July 2017

Youya Wang

9

1 reference

28 July 2017

Jingyi Hu

10

1 reference

28 July 2017

Vaidehi Krishnan

11

1 reference

28 July 2017

Zhongjun Zhou

12

1 reference

28 July 2017

Zimei Wang

13

1 reference

28 July 2017

publication date

14 February 2014

1 reference

28 July 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Cell Cycle

1 reference

28 July 2017

volume

13

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28 July 2017

issue

8

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28 July 2017

page(s)

1237-1247

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describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4049960/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model

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Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells

21 June 2018

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Ubiquitin ligase RNF123 mediates degradation of heterochromatin protein 1α and β in lamin A/C knock-down cells

21 June 2018

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Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria.

21 June 2018

1 reference

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The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice

21 June 2018

1 reference

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21 June 2018

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Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells

21 June 2018

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Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

21 June 2018

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Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin

21 June 2018

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Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10

21 June 2018

1 reference

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An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria

21 June 2018

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Pseudo-DNA damage response in senescent cells

21 June 2018

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A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization

21 June 2018

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Mobilization and recruitment of HP1: a bimodal response to DNA breakage.

21 June 2018

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Rapamycin decelerates cellular senescence

21 June 2018

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Heterochromatin protein 1 is recruited to various types of DNA damage.

21 June 2018

1 reference

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The impact of heterochromatin on DSB repair

21 June 2018

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Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated.

21 June 2018

1 reference

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ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin

21 June 2018

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Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A.

21 June 2018

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Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

21 June 2018

1 reference

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Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

21 June 2018

1 reference

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Lamin A-dependent nuclear defects in human aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Nuclear envelope proteins and chromatin arrangement: a pathogenic mechanism for laminopathies.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

21 June 2018

1 reference

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Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Genomic instability in laminopathy-based premature aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Lamin a truncation in Hutchinson-Gilford progeria.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Self-interaction of heterochromatin protein 1 is required for direct binding to histone methyltransferase, SUV39H1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Nuclear lamins: building blocks of nuclear architecture

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Dynamic associations of heterochromatin protein 1 with the nuclear envelope

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Inner nuclear membrane protein LBR preferentially interacts with DNA secondary structures and nucleosomal linker

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Nuclear lamins: their structure, assembly, and interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy

21 June 2018

1 reference

HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response.

21 January 2018

1 reference

Defective ATM-Kap-1-mediated chromatin remodeling impairs DNA repair and accelerates senescence in progeria mouse model

21 January 2018

1 reference

Pre-Lamin A processing is linked to heterochromatin organization.

21 January 2018

1 reference

Lamins are rapamycin targets that impact human longevity: a study in centenarians

21 January 2018

1 reference

Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049960

30 October 2018

Identifiers

DOI

10.4161/CC.28105

1 reference

28 July 2017

1 reference

28 July 2017

1 reference