(Q33728384)

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E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma via promoting ubiquitination-mediated degradation of RARα.

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Europe PubMed Central

PubMed publication ID

28 July 2017

E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma via promoting ubiquitination-mediated degradation of RARα. (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

protein ubiquitination

1 reference

based on heuristic

inferred from title

author name string

Lei Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Qian Zhou

2

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Ning Zhang

3

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Weixu Li

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Meidan Ying

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Wanjing Ding

6

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Bo Yang

7

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Qiaojun He

8

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

publication date

17 February 2014

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1277-1287

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Molecular pathways: current role and future directions of the retinoic acid pathway in cancer prevention and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Gene expression profiling combined with bioinformatics analysis identify biomarkers for Parkinson disease

1 reference

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21 June 2018

Bortezomib sensitizes human acute myeloid leukemia cells to all-trans-retinoic acid-induced differentiation by modifying the RARα/STAT1 axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Retinoic acid regulates commitment of undifferentiated mesenchymal stem cells into osteoblasts and adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

The MET oncogene transforms human primary bone-derived cells into osteosarcomas by targeting committed osteo-progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

p38αMAPK interacts with and inhibits RARα: suppression of the kinase enhances the therapeutic activity of retinoids in acute myeloid leukemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Cyr61 expression in osteosarcoma indicates poor prognosis and promotes intratibial growth and lung metastasis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Review of therapeutic strategies for osteosarcoma, chondrosarcoma, and Ewing's sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

E2F1-dependent oncogenic addiction of melanoma cells to MDM2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Retinoic acid-induced Smad3 expression is required for the induction of osteoblastogenesis of mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

The molecular pathogenesis of osteosarcoma: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Inhibition of all‐Trans‐retinoic acid‐induced proteasome activation potentiates the differentiating effect of retinoid in acute myeloid leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Retinoid-suppressed phosphorylation of RARalpha mediates the differentiation pathway of osteosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Regulation of E2F1-induced apoptosis by the nucleolar protein RRP1B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Deregulated expression of E2F1 promotes proteolytic degradation of tumor suppressor p73 and inhibits its transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

ROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Differentiation of osteoblasts and osteocytes from mesenchymal stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Developmental origin of fat: tracking obesity to its source.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Estrogen-regulated gene networks in human breast cancer cells: involvement of E2F1 in the regulation of cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Low E2F1 transcript levels are a strong determinant of favorable breast cancer outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

E2F1 death pathways as targets for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Osteosarcoma and osteoblastic differentiation: a new perspective on oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Clinical trials with retinoids for breast cancer chemoprevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Mesenchymal, but not hematopoietic, stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Down-regulation of inducible nitric oxide synthase by lysophosphatidic acid in human respiratory epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Life and death decisions by E2F-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Retinoid therapy of high-risk neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

E2Fs regulate adipocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Nuclear receptor agonists as potential differentiation therapy agents for human osteosarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

The promise of retinoids to fight against cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

A transcriptionally inactive E2F-1 targets the MDM family of proteins for proteolytic degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Retinoic acid induces proteasome-dependent degradation of retinoic acid receptor alpha (RARalpha) and oncogenic RARalpha fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Inhibition of in vitro myogenic differentiation by cellular transcription factor E2F1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

E2F-1 blocks terminal differentiation and causes proliferation in transgenic megakaryocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

Retinoids in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

21 June 2018

All-trans retinoic acid (atRA) differentially induces apoptosis in matched primary and metastatic melanoma cells -- a speculation on damage effect of atRA via mitochondrial dysfunction and cell cycle redistribution

1 reference

https://api.crossref.org/works/10.4161%2FCC.28190

21 January 2018

Retinoids and breast cancer: new clues to increase their activity and selectivity

1 reference

https://api.crossref.org/works/10.4161%2FCC.28190

21 January 2018

Inhibition of Kaposi's sarcoma in vivo by fenretinide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4049964

30 October 2018

The development of biologic end points in patients treated with differentiation agents: an experience of retinoids in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24608861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone-specific alkaline phosphatase in plasma as tumour marker for osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24608861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An expression signature classifies chemotherapy-resistant pediatric osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24608861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteopontin promotes integrin activation through outside-in and inside-out mechanisms: OPN-CD44V interaction enhances survival in gastrointestinal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24608861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis in human esophageal cancer cells by sequential transfer of the wild-type p53 and E2F-1 genes: involvement of p53 accumulation via ARF-mediated MDM2 down-regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24608861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor E2F-1 acts as a growth-promoting factor and is associated with adverse prognosis in non-small cell lung carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/24608861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of osteopontin expression in osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/24608861

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/CC.28190

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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