(Q38296622)

1 September 2017

A transcriptionally inactive E2F-1 targets the MDM family of proteins for proteolytic degradation (English)

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1 September 2017

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G D Strachan

1

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1 September 2017

R Rallapalli

2

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1 September 2017

B Pucci

3

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1 September 2017

T P Lafond

4

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1 September 2017

D J Hall

5

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1 September 2017

language of work or name

English

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publication date

1 December 2001

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Journal of Biological Chemistry

1 September 2017

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1 September 2017

276

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1 September 2017

45677-45685

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1 September 2017

49

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DP and E2F proteins: components of a heterodimeric transcription factor implicated in cell cycle control

1 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Role of the Rb/E2F pathway in cell growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Regulation of transcription by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

p53 and E2F-1 cooperate to mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Interaction between the retinoblastoma protein and the oncoprotein MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Apoptotic and growth-promoting activity of E2F modulated by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Mdm-2: "big brother" of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Repression of p53-mediated transcription by MDM2: a dual mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

MdmX protects p53 from Mdm2-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

MDM2 interacts with MDMX through their RING finger domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Isolation of a novel cDNA encoding a zinc-finger protein that binds to two sites within the c-myc promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Lactacystin, proteasome function, and cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

A unique cathepsin-like protease isolated from CV-1 cells is involved in rapid degradation of retinoblastoma susceptibility gene product, RB, and transcription factor SP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Regulation of BRCA1 by protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Comparative study of the p53-mdm2 and p53-MDMX interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Transcriptional repression from the c-myc P2 promoter by the zinc finger protein ZF87/MAZ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

Bafilomycin A1 inhibits the targeting of lysosomal acid hydrolases in cultured hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103765200

21 January 2018

Identifiers

DOI

10.1074/JBC.M103765200

1 reference

1 September 2017

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