(Q33729666)

29 July 2017

title

Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells (English)

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29 July 2017

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10

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15

Lior Pachter

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Rudolf Jaenisch

16

Rudolf Jaenisch

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Dirk Hockemeyer

Dirk Hockemeyer

17

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Philip D Gregory

Philip D Gregory

14

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Edward Rebar

12

Edward J Rebar

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29 July 2017

13

Fyodor D Urnov

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29 July 2017

9

Hans Clevers

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29 July 2017

Ryan Forster

1

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29 July 2017

Kunitoshi Chiba

2

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29 July 2017

Lorian Schaeffer

3

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29 July 2017

Samuel G Regalado

4

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29 July 2017

Christine S Lai

5

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29 July 2017

Qing Gao

6

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29 July 2017

Samira Kiani

7

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29 July 2017

Henner F Farin

8

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29 July 2017

Andy Chan

11

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29 July 2017

publication date

3 June 2014

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29 July 2017

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29 July 2017

volume

2

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29 July 2017

issue

6

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29 July 2017

page(s)

838-852

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29 July 2017

cites work

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21 June 2018

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Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury

21 June 2018

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21 June 2018

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21 June 2018

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A gutsy task: generating intestinal tissue from human pluripotent stem cells

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5

21 June 2018

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21 June 2018

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Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5⁺ stem cell

21 June 2018

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21 June 2018

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21 June 2018

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Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

21 June 2018

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Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

21 June 2018

1 reference

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Genetic engineering of human pluripotent cells using TALE nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

21 June 2018

1 reference

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Targeting SOX17 in human embryonic stem cells creates unique strategies for isolating and analyzing developing endoderm

21 June 2018

1 reference

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Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Differential expression analysis for sequence count data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Transcriptional dynamics of endodermal organ formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

A drug-inducible system for direct reprogramming of human somatic cells to pluripotency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Identification of stem cells in small intestine and colon by marker gene Lgr5

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Mitogenic influence of human R-spondin1 on the intestinal epithelium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Isolation and in vitro expansion of human colonic stem cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Intestinal lineage commitment of embryonic stem cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050346

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24936470

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STEMCR.2014.05.001

1 reference

release_l7ve7u5qn5gllbr7glk54nid6i

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/l7ve7u5qn5gllbr7glk54nid6i

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4050346

1 reference

29 July 2017

1 reference