(Q28291898)

1

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Caroline L Wiegerinck

2

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Hugo R de Jonge

3

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Inez Bronsveld

4

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Hettie M Janssens

5

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Karin M de Winter-de Groot

6

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Arianne M Brandsma

7

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Nienke W M de Jong

8

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Marcel J C Bijvelds

9

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Bob J Scholte

10

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Edward E S Nieuwenhuis

11

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Stieneke van den Brink

12

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Cornelis K van der Ent

14

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Sabine Middendorp

15

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Jeffrey M Beekman

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

16

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language of work or name

English

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publication date

July 2013

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published in

Nature Medicine

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volume

19

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issue

7

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page(s)

939-45

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cites work

1 reference

Identification of the cystic fibrosis gene: chromosome walking and jumping

21 April 2017

1 reference

21 April 2017

1 reference

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

21 April 2017

1 reference

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 April 2017

1 reference

Rescue of ΔF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway

21 April 2017

1 reference

CFTR inhibitors for treating diarrheal disease

21 April 2017

1 reference

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

21 April 2017

1 reference

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 April 2017

1 reference

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

21 April 2017

1 reference

Identification of the cystic fibrosis gene: genetic analysis

21 April 2017

1 reference

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

21 January 2018

1 reference

CFTR function and prospects for therapy

21 January 2018

1 reference

A CFTR potentiator in patients with cystic fibrosis and the G551D mutation

21 January 2018

1 reference

Correction of both NBD1 energetics and domain interface is required to restore ΔF508 CFTR folding and function

21 January 2018

1 reference

PTC124 targets genetic disorders caused by nonsense mutations

21 January 2018

1 reference

Ataluren (PTC124) induces cystic fibrosis transmembrane conductance regulator protein expression and activity in children with nonsense mutation cystic fibrosis

21 January 2018

1 reference

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.

21 January 2018

1 reference

Ivacaftor in subjects with cystic fibrosis who are homozygous for the F508del-CFTR mutation

21 January 2018

1 reference

Intestinal ion transport and the pathophysiology of diarrhea

21 January 2018

1 reference

Ion transport in the small intestine

21 January 2018

1 reference

Chloride secretion in a morphologically differentiated human colonic cell line that expresses the epithelial Na+ channel

21 January 2018

1 reference

Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy

21 January 2018

1 reference

Production of a severe cystic fibrosis mutation in mice by gene targeting

21 January 2018

1 reference

A delta F508 mutation in mouse cystic fibrosis transmembrane conductance regulator results in a temperature-sensitive processing defect in vivo

21 January 2018

1 reference

Mouse models of cystic fibrosis: phenotypic analysis and research applications

21 January 2018

1 reference

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

21 January 2018

1 reference

Rescue of DeltaF508 and other misprocessed CFTR mutants by a novel quinazoline compound

21 January 2018

1 reference

Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.

21 January 2018

1 reference

Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene

21 January 2018

1 reference

Genotype and phenotype in cystic fibrosis

21 January 2018

1 reference

Ex vivo CF diagnosis by intestinal current measurements (ICM) in small aperture, circulating Ussing chambers

21 January 2018

1 reference

New clinical diagnostic procedures for cystic fibrosis in Europe

21 January 2018

1 reference

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.

21 January 2018

1 reference

Functional Cftr in crypt epithelium of organotypic enteroid cultures from murine small intestine

21 January 2018

1 reference

Trafficking of immature DeltaF508-CFTR to the plasma membrane and its detection by biotinylation

21 January 2018

1 reference

Coupling of cell volume and membrane potential changes to fluid secretion in a model of renal cysts

21 January 2018

1 reference

Fluid and electrolyte transport by cultured human airway epithelia

21 January 2018

1 reference

The K+ channel opener 1-EBIO potentiates residual function of mutant CFTR in rectal biopsies from cystic fibrosis patients

21 January 2018

1 reference

Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

21 January 2018

1 reference

Syntenin-mediated regulation of Sox4 proteasomal degradation modulates transcriptional output

21 January 2018

1 reference

Impact of the cystic fibrosis mutation F508del-CFTR on renal cyst formation and growth

21 January 2018

1 reference

A small molecule CFTR inhibitor produces cystic fibrosis-like submucosal gland fluid secretions in normal airways

21 January 2018

1 reference

12 December 2020

Spectrum of mutations in the CFTR gene of patients with classical and atypical forms of cystic fibrosis from southwestern Sweden: identification of 12 novel mutations

1 reference

12 December 2020

Personalized medicine in cystic fibrosis: dawning of a new era

1 reference

12 December 2020

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

1 reference

12 December 2020

Identification of the L927P and delta L1260 mutations in the CFTR gene

1 reference

12 December 2020

Association between genotype and pulmonary phenotype in cystic fibrosis patients with severe mutations

1 reference

12 December 2020

cAMP-stimulated ion currents in Xenopus oocytes expressing CFTR cRNA

1 reference

12 December 2020