(Q33730599)

29 July 2017

title

Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1. (English)

1 reference

29 July 2017

1 reference

1 reference

Haoyue Zhang

1

1 reference

29 July 2017

Zheng-Mei Xiong

series ordinal

2

1 reference

29 July 2017

Kan Cao

series ordinal

3

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29 July 2017

language of work or name

English

0 references

publication date

19 May 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

1 reference

29 July 2017

volume

111

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29 July 2017

issue

22

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29 July 2017

page(s)

E2261-70

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53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.

29 July 2017

cites work

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Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model

21 June 2018

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Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport

21 June 2018

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An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells

21 June 2018

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21 June 2018

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Topoisomerase I poisoning results in PARP-mediated replication fork reversal

21 June 2018

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Poly(ADP-Ribose) polymerase 1 (PARP-1) regulates ribosomal biogenesis in Drosophila nucleoli

21 June 2018

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DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndrome

21 June 2018

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

21 June 2018

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Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells

21 June 2018

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Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

21 June 2018

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The defective nuclear lamina in Hutchinson-gilford progeria syndrome disrupts the nucleocytoplasmic Ran gradient and inhibits nuclear localization of Ubc9.

21 June 2018

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Identification of poly (ADP-ribose) polymerase-1 (PARP-1) as a novel Kruppel-like factor 8-interacting and -regulating protein

21 June 2018

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Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

21 June 2018

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Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells.

21 June 2018

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A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

21 June 2018

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Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.

21 June 2018

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Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging

21 June 2018

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

21 June 2018

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Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A.

21 June 2018

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A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

21 June 2018

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Death through a tragedy: mitotic catastrophe

21 June 2018

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Phenotype and course of Hutchinson-Gilford progeria syndrome

21 June 2018

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The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin

21 June 2018

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PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

21 June 2018

1 reference

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DNA damage, cellular senescence and organismal ageing: causal or correlative?

21 June 2018

1 reference

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Regulation and characteristics of vascular smooth muscle cell phenotypic diversity.

21 June 2018

1 reference

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Regulation of vascular smooth muscle cell differentiation

21 June 2018

1 reference

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A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells

21 June 2018

1 reference

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Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging

21 June 2018

1 reference

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Xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome: a complex genotype-phenotype relationship

21 June 2018

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Human laminopathies: nuclei gone genetically awry

21 June 2018

1 reference

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

21 June 2018

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Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

21 June 2018

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Lamin A-dependent nuclear defects in human aging

21 June 2018

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Prelamin A and lamin A appear to be dispensable in the nuclear lamina

21 June 2018

1 reference

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Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Genomic instability in laminopathy-based premature aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Pathways of DNA double-strand break repair during the mammalian cell cycle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Camptothecins: a review of their chemotherapeutic potential

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

21 June 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1320843111

Defective ATM-Kap-1-mediated chromatin remodeling impairs DNA repair and accelerates senescence in progeria mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1320843111

Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1320843111

A highly efficient method to differentiate smooth muscle cells from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1320843111

Mitotic catastrophe: a mechanism for avoiding genomic instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1320843111

Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1320843111

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050581

30 October 2018

Identifiers

DOI

10.1073/PNAS.1320843111

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference