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LEDGF hybrids efficiently retarget lentiviral integration into heterochromatin
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scholarly article
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
title
LEDGF hybrids efficiently retarget lentiviral integration into heterochromatin
(English)
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
author
Zeger Debyser
series ordinal
8
object named as
Zeger Debyser
0 references
Frederic D. Bushman
object named as
Frederic D Bushman
series ordinal
7
0 references
author name string
Rik Gijsbers
series ordinal
1
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
Keshet Ronen
series ordinal
2
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
Sofie Vets
series ordinal
3
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
Nirav Malani
series ordinal
4
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
Jan De Rijck
series ordinal
5
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
Melissa McNeely
series ordinal
6
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
publication date
5 January 2010
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
published in
Molecular Therapy
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stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
volume
18
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stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
page(s)
552-560
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stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
issue
3
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
cites work
LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors
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PubMed Central
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21 June 2018
Highly efficient multicistronic lentiviral vectors with peptide 2A sequences
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21 June 2018
A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75
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PubMed Central
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21 June 2018
Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.
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PubMed Central
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21 June 2018
The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure
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PubMed Central
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21 June 2018
Combinatorial patterns of histone acetylations and methylations in the human genome
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21 June 2018
Role of PSIP1/LEDGF/p75 in lentiviral infectivity and integration targeting
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PubMed Central
reference URL
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21 June 2018
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
HIV integration site selection: analysis by massively parallel pyrosequencing reveals association with epigenetic modifications
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PubMed Central
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21 June 2018
High-resolution profiling of histone methylations in the human genome
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Selection of target sites for mobile DNA integration in the human genome
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PubMed Central
reference URL
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21 June 2018
LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Human heterochromatin proteins form large domains containing KRAB-ZNF genes
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PubMed Central
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21 June 2018
Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication
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PubMed Central
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21 June 2018
Modulating target site selection during human immunodeficiency virus DNA integration in vitro with an engineered tethering factor
1 reference
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PubMed Central
reference URL
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21 June 2018
An essential role for LEDGF/p75 in HIV integration
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
The integration profile of EIAV-based vectors
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PubMed Central
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21 June 2018
Multi-miRNA hairpin method that improves gene knockdown efficiency and provides linked multi-gene knockdown
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Retroviral DNA integration: HIV and the role of LEDGF/p75.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Determinants of histone H1 mobility and chromatin binding in living cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
A role for LEDGF/p75 in targeting HIV DNA integration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Upscaling of lentiviral vector production by tangential flow filtration
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
The dynamics of histone H1 function in chromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
HP1 and the dynamics of heterochromatin maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
HIV-1 integration in the human genome favors active genes and local hotspots
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
LEDGF, a survival factor, activates stress-related genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
The family of hepatoma-derived growth factor proteins: characterization of a new member HRP-4 and classification of its subfamilies
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
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21 June 2018
Autoantibodies to DFS 70 kd/transcription coactivator p75 in atopic dermatitis and other conditions
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
21 June 2018
Correct integration mediated by integrase-LexA fusion proteins incorporated into HIV-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
30 October 2018
Cell cycle behavior of human HP1 subtypes: distinct molecular domains of HP1 are required for their centromeric localization during interphase and metaphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839429
retrieved
10 December 2018
Immunolocalization of HP1 proteins in metaphasic mammalian chromosomes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20195265
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/MT.2010.36
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
PMCID
2839429
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
PubMed ID
20195265
1 reference
stated in
Q5412157
PubMed ID
20195265
retrieved
29 July 2017
ResearchGate publication ID
41657340
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