(Q33740026)

English

Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

author name string

Feng-Hou Gao

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Xiao-Hui Hu

2

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29 July 2017

Wei Li

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Hua Liu

4

1 reference

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29 July 2017

Yan-Jie Zhang

5

1 reference

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29 July 2017

Zhu-Ying Guo

6

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Mang-Hua Xu

7

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Shi-Ting Wang

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Bin Jiang

9

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Feng Liu

10

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ying-Zheng Zhao

11

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Yong Fang

12

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Fang-Yuan Chen

13

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29 July 2017

Ying-Li Wu

14

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29 July 2017

language of work or name

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publication date

6 November 2010

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Europe PubMed Central

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29 July 2017

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Europe PubMed Central

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29 July 2017

10

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29 July 2017

610

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

https://scigraph.springernature.com/pub.10.1186/1471-2407-10-610

0 references

Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Current management of colorectal hepatic metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Development of the pan-DAC inhibitor panobinostat (LBH589): successes and challenges

1 reference

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14 July 2018

Current place of high-dose irinotecan chemotherapy in patients with metastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Curable metastatic colorectal cancer: recommended paradigms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Apoptosis inducing and differentiation enhancement effect of oridonin on the all-trans-retinoic acid-sensitive and -resistant acute promyelocytic leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Neoadjuvant chemotherapy and targeted therapy in patients with liver metastases from colorectal cancer; medical oncologist's point of view.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Reactive oxygen species mediate oridonin-induced HepG2 apoptosis through p53, MAPK, and mitochondrial signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Tanshinone I effectively induces apoptosis in estrogen receptor-positive (MCF-7) and estrogen receptor-negative (MDA-MB-231) breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Targeting prostate cancer based on signal transduction and cell cycle pathways.

1 reference

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14 July 2018

Terpenoids: natural inhibitors of NF-kappaB signaling with anti-inflammatory and anticancer potential

1 reference

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14 July 2018

Aberrant epigenetic patterns in the etiology of gastrointestinal cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Current and future clinical strategies in colon cancer prevention and the emerging role of chemoprevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential

1 reference

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14 July 2018

Targeting aberrant chromatin structure in colorectal carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Oridonin induced apoptosis through Akt and MAPKs signaling pathways in human osteosarcoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Strong HLA-DR antigen expression on cancer cells relates to better prognosis of colorectal cancer patients: Possible involvement of c-myc suppression by interferon-gamma in situ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Src inhibits adriamycin-induced senescence and G2 checkpoint arrest by blocking the induction of p21waf1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the chinese herb Rabdosia rubescens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Potential anticancer activity of tanshinone IIA against human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Hallmarks of senescence in carcinogenesis and cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Epigenetic changes in colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Phenylbutyrate and phenylacetate induce differentiation and inhibit proliferation of human medulloblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Senescence, apoptosis and therapy--cutting the lifelines of cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model

1 reference

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14 July 2018

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Making decisions through Myc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Terpenoid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992521

14 July 2018

Studies on the cell-immunosuppressive mechanism of Oridonin from Isodon serra.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-610

21 January 2018

Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecologic cancer cells

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-610

21 January 2018

Non-invasive detection of c-myc p64, c-myc p67 and c-erbb-2 in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-610

21 January 2018

p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells

1 reference

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30 October 2018

c-Jun N-terminal kinase mediates AML1-ETO protein-induced connexin-43 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21054888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of p16/p21/p27 and cyclin D1/D3, and their relationships to cell proliferation, apoptosis, and tumour progression in invasive ductal carcinoma of the breast

1 reference

https://pubmed.ncbi.nlm.nih.gov/21054888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21054888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21054888

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2407-10-610

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Dimensions Publication ID

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2407-10-610

9 September 2019

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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