(Q33742243)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10503815%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

review article

1 reference

title

Differential kinetics of phenytoin in elderly patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10503815%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10503815%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

author name string

K A Bachmann

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10503815%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

publication date

1 September 1999

1 reference

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31 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10503815%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10503815%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10503815%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

page(s)

235-250

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10503815%20AND%20SRC:MED&resulttype=core&format=json

Aging and drug interactions. II. Effect of phenytoin and smoking on the oxidation of theophylline and cortisol in healthy men

31 October 2019

cites work

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Pharmacokinetic and pharmacodynamic principles of drug therapy in old age. Part 1.

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Effect of barbiturate therapy on phenytoin pharmacokinetics

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Effect of age on liver function

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Dual effect of valproic acid on the pharmacokinetics of phenytoin

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Ticlopidine impairs phenytoin clearance: a case report

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The aging liver. Drug clearance and an oxygen diffusion barrier hypothesis.

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Interaction between amiodarone and lidocaine.

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Effect of fluconazole on the disposition of phenytoin

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Drug binding in sera deficient in lipoproteins, albumin or orosomucoid

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Influence of acute viral hepatitis on disposition and plasma binding of tolbutamide

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Fluoxetine inhibition of phenytoin metabolism

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Influence of rifampicin and isoniazid on the kinetics of phenytoin

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Steady-state interaction between amiodarone and phenytoin in normal subjects

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Alteration of drug-protein binding in renal disease

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The Effect of Different Sulfonamides on Phenytoin Metabolism in Man

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Elevated serum phenytoin concentrations associated with coadministration of sertraline

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Increased Free Phenytoin Concentrations in Predialysis Serum Compared to Postdialysis Serum in Patients with Uremia Treated with Hemodialysis: Role of Uremic Compounds

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Evaluation of methods for estimating population pharmacokinetic parameters. I. Michaelis-menten model: Routine clinical pharmacokinetic data

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Diphenylhydantoin metabolism. A prospective review

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Clinical importance of the interaction of phenytoin and isoniazid: a report from the Boston Collaborative Drug Surveillance Program

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Age and sex effects on energy expenditure.

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Binding of drugs to human serum albumin. XIV. The theoretical basis for the interaction between phenytoin and valproate

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Contrasting effects of fluconazole and ketoconazole on phenytoin and testosterone disposition in man

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Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9

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12 December 2020

Inhibition of CYP2C9 by selective serotonin reuptake inhibitors in vitro: studies of phenytoin p-hydroxylation

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12 December 2020

Plasma Protein Binding of Drugs as a Function of Age in Adult Human Subjects

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12 December 2020

Pharmacokinetic basis of age-related changes in sensitivity to toxicants

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12 December 2020

Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations

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Inhibition and induction of cytochrome P4502E1-catalyzed oxidation by isoniazid in humans

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Clinical pharmacokinetics of antidepressants in the elderly. Therapeutic implications

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Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy

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Effect of age and gender on the activity of human hepatic CYP3A

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Human CYP2C9 and CYP2A6 mediate formation of the hepatotoxin 4-ene-valproic acid

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Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.

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Differential inhibition of individual human liver cytochromes P-450 by cimetidine

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Clinical pharmacokinetic considerations in the elderly. An update

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Oral phenytoin pharmacokinetics during omeprazole therapy

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Age and cytochrome P450-linked drug metabolism in humans: an analysis of 226 subjects with equal histopathologic conditions

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Hepatic drug metabolism and aging

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12 December 2020

Energy metabolism, body size, and problems of scaling.

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12 December 2020

A study of the pharmacokinetics of phenytoin (diphenylhydantoin) in epileptic patients, and the development of a nomogram for making dose increments

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12 December 2020

Phenytoin dosage individualization--five methods compared in the elderly.

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12 December 2020

Distribution of drugs over whole blood: II. The transport function of whole blood for phenytoin.

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12 December 2020

The effect of age upon liver volume and apparent liver blood flow in healthy man.

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12 December 2020

Age and phenytoin kinetics in adult epileptics

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12 December 2020

Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes

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12 December 2020

Effect of aging and cigarette smoking on antipyrine and indocyanine green elimination

1 reference

12 December 2020

Steady-state pharmacokinetics of phenytoin from routinely collected patient data

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12 December 2020

Morphine and phenytoin binding to plasma proteins in renal and hepatic failure

1 reference

12 December 2020

Concentrations and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin.

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12 December 2020

Averaging pharmacokinetic parameter estimates from experimental studies: statistical theory and application

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12 December 2020

Cytochrome P450 isozymes and antiepileptic drug interactions

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12 December 2020

Predicting individual phenytoin dosage

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12 December 2020

Plasma protein binding of diphenylhydantoin in man. Interaction with other drugs and the effect of temperature and plasma dilution

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12 December 2020

Differentiated effects of liver cirrhosis on the albumin binding sites for diazepam, salicylic acid and warfarin

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12 December 2020

Phenytoin pharmacokinetics in young and older adults

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12 December 2020

Simulation for population analysis of Michaelis-Menten elimination kinetics.

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12 December 2020

Valproic acid in epilepsy: Clinical and pharmacological effects

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12 December 2020

Phenobarbital does not alter phenytoin steady-state serum concentration or pharmacokinetics

1 reference

12 December 2020

Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation

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12 December 2020

Plasma protein binding of phenytoin in the aged: in vivo studies

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12 December 2020

Reduction of phenytoin clearance caused by cimetidine

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12 December 2020

Explicit criteria for determining potentially inappropriate medication use by the elderly. An update

1 reference

12 December 2020

Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

1 reference

12 December 2020

The disposition of antipyrine and its metabolites in young and elderly healthy volunteers

1 reference

12 December 2020

Pharmacokinetics of phenytoin in routine clinic patients in Malaysia

1 reference

12 December 2020

Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae

1 reference

12 December 2020

Population pharmacokinetics of phenytoin in Japanese patients with epilepsy: analysis with a dose-dependent clearance model.

1 reference

12 December 2020

Seizures and epilepsy in older patients: evaluation and management

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12 December 2020

Effect of age and sex on the plasma binding of acidic and basic drugs

1 reference

12 December 2020

Phenytoin causes a rapid increase in 6 beta-hydroxycortisol urinary excretion in humans--a putative measure of CYP3A induction

1 reference

12 December 2020

Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo

1 reference

12 December 2020

Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions

1 reference

12 December 2020

Effect of age, height, weight and sex on serum phenytoin concentration in epileptic patients

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12 December 2020

Pharmacokinetic drug interactions of new antidepressants: a review of the effects on the metabolism of other drugs

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12 December 2020

Interactions between anticonvulsants and other commonly prescribed drugs

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12 December 2020

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12 December 2020

Management of seizures in the elderly: a survey of UK geriatricians.

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12 December 2020

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12 December 2020

Stereoselective 4'-hydroxylation of phenytoin: relationship to (S)-mephenytoin polymorphism in Japanese

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12 December 2020

Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

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12 December 2020

Aging and determinants of hepatic drug clearance

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12 December 2020

Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

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12 December 2020

Dose-dependent effect of cimetidine on phenytoin kinetics

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12 December 2020

Diphenylhydantoin intoxication attendant to slow inactivation of isoniazid.

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12 December 2020

Derivation and evaluation of an equation for prediction of free phenytoin concentration in patients co-medicated with valproic acid.

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12 December 2020

Two dimensional immunoelectrophoresis of human serum proteins for the investigation of protein drugs

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12 December 2020

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

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12 December 2020

Changes in drug metabolism with increasing age: 2. phenytoin clearance and protein binding

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12 December 2020

Molecular mechanisms of genetic polymorphisms of drug metabolism

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12 December 2020

Carbamazepine-phenytoin interaction: elevation of plasma phenytoin concentrations due to carbamazepine comedication

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12 December 2020

Disposition of Antipyrine and Phenytoin Correlated with Age and Liver Volume in Man

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12 December 2020

Ticlopidine inhibition of phenytoin metabolism mediated by potent inhibition of CYP2C19

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12 December 2020

Drug interactions in the elderly. How multiple drug use increases risk exponentially

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12 December 2020

Clinical utility of six methods of predicting phenytoin doses and plasma concentrations

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12 December 2020

Inappropriate medication is a major cause of adverse drug reactions in elderly patients

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12 December 2020

Pharmacological implications of microsomal enzyme induction.

1 reference

12 December 2020

Aging and drug interactions. III. Individual and combined effects of cimetidine and cimetidine and ciprofloxacin on theophylline metabolism in healthy male and female nonsmokers.

1 reference

12 December 2020

Absence of effect of sertraline on the pharmacokinetics and pharmacodynamics of phenytoin

1 reference

12 December 2020

Binding of fosphenytoin, phosphate ester pro drug of phenytoin, to human serum proteins and competitive binding with carbamazepine, diazepam, phenobarbital, phenylbutazone, phenytoin, valproic acid or warfarin

1 reference

12 December 2020

Phenytoin dose adjustment in epileptic patients

1 reference

12 December 2020

Dual effects of carbamazepine-phenytoin interaction

1 reference

12 December 2020

Co-regulation of phenytoin and tolbutamide metabolism in humans

1 reference

12 December 2020

Stereochemistry of aromatic phenytoin hydroxylation in various drug hydroxylation phenotypes in humans

1 reference

12 December 2020

Population pharmacokinetics of phenytoin in Singapore Chinese.

1 reference

12 December 2020