(Q41619585)

5 October 2017

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title

Clinical pharmacokinetic considerations in the elderly. An update (English)

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5 October 2017

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Kinirons MT

1

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5 October 2017

Crome P

series ordinal

2

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5 October 2017

language of work or name

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1 October 1997

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Clinical Pharmacokinetics

5 October 2017

published in

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5 October 2017

volume

33

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5 October 2017

issue

4

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5 October 2017

page(s)

302-312

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Ethnic differences in response to morphine

5 October 2017

cites work

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12 December 2020

Purification of multiple forms of cytochrome P450 from a human brain and reconstitution of catalytic activities

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12 December 2020

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

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12 December 2020

The influence of age, liver size and enantiomer concentrations on warfarin requirements

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12 December 2020

Age-associated stereoselective alterations in hexobarbital metabolism

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12 December 2020

CYP3A gene expression in human gut epithelium

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12 December 2020

The association of age and frailty with paracetamol conjugation in man

1 reference

12 December 2020

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

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12 December 2020

Drug interactions with grapefruit juice

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12 December 2020

Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae

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12 December 2020

Anti-liver microsomes autoantibodies and dihydralazine-induced hepatitis: specificity of autoantibodies and inductive capacity of the drug

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12 December 2020

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12 December 2020

Hepatic drug metabolism and ageing

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12 December 2020

Terodiline causes polymorphic ventricular tachycardia due to reduced heart rate and prolongation of QT interval

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12 December 2020

Cyclosporin metabolism by human gastrointestinal mucosal microsomes

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12 December 2020

Interaction of citrus juices with felodipine and nifedipine

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12 December 2020

Expression of cytochrome P450 3A in amphibian, rat, and human kidney

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12 December 2020

The association of age with aspirin esterase activity in human liver

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12 December 2020

Cyclosporin-erythromycin interaction in renal transplant patients

1 reference

12 December 2020

Identification of an inducible form of cytochrome P-450 in human liver

1 reference

12 December 2020

Prescribing for the elderly. Part I: Sensitivity of the elderly to adverse drug reactions

1 reference

12 December 2020

Pethidine pharmacokinetics after intramuscular dose: a comparison in Caucasian, Chinese and Nepalese patients

1 reference

12 December 2020

Plasma aspirin esterase: the influence of old age and frailty

1 reference

12 December 2020

Frequency distribution of dapsone N-hydroxylase, a putative probe for P4503A4 activity, in a white population

1 reference

12 December 2020

Immunohistochemical localization of cytochrome P450 3A in human pulmonary carcinomas and normal bronchial tissue

1 reference

12 December 2020

Clinical pharmacokinetic considerations in the elderly. An update

1 reference

12 December 2020

Drugs and the liver. Part III: Ageing of the liver and the metabolism of drugs

1 reference

12 December 2020

The relationship between phenazone (antipyrine) metabolite formation and theophylline metabolism in healthy and frail elderly women

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12 December 2020

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

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12 December 2020

Ethnic differences in drug disposition and responsiveness

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12 December 2020

Induction of polymorphic 4'-hydroxylation of S-mephenytoin by rifampicin

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12 December 2020

Effect of grapefruit juice on blood cyclosporin concentration

1 reference

12 December 2020

Intra- and interethnic variability in reduced haloperidol to haloperidol ratios

1 reference

12 December 2020

Age, smoking and the activity of the mono-oxygenase aryl hydrocarbon hydroxylase in isolated human peripheral blood monocytes

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12 December 2020

Effects of age and cigarette smoking on propranolol disposition

1 reference

12 December 2020

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA.

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12 December 2020

Lack of effect of ageing on the stereochemical disposition of propranolol

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12 December 2020

Effect of age and gender on the activity of human hepatic CYP3A

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12 December 2020

Oxidation of dihydropyridine calcium channel blockers and analogues by human liver cytochrome P-450 IIIA4.

1 reference

12 December 2020

Cytochromes P-450 in the intestinal mucosa of man

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12 December 2020

Interethnic variation of drug metabolism

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12 December 2020

Hepatic drug metabolism and aging

1 reference

12 December 2020

Effects of interferon-alpha monotherapy on hepatic drug metabolism in cancer patients

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12 December 2020

Tolerability and steady-state pharmacokinetics of terodiline and its main metabolites in elderly patients with urinary incontinence

1 reference

12 December 2020

Effects of age and gender on in vitro properties of human liver microsomal monooxygenases

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12 December 2020

The human hepatic cytochromes P450 involved in drug metabolism

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12 December 2020

Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6

1 reference

12 December 2020

Oxidative metabolism of hexobarbital in human liver: relationship to polymorphic S-mephenytoin 4-hydroxylation

1 reference

12 December 2020

Genetic predisposition to bladder cancer: ability to hydroxylate debrisoquine and mephenytoin as risk factors

1 reference

12 December 2020

Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxylation of chlorzoxazone: a putative measure of CYP2E1 activity

1 reference

12 December 2020

Effect of ageing upon warfarin dose requirements: a longitudinal study.

1 reference

12 December 2020

Characterization of human cytochrome P450 enzymes

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12 December 2020

Inhibition of oral contraceptive steroid-metabolizing enzymes by steroids and drugs

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12 December 2020

Detection of human lung cytochromes P450 that are immunochemically related to cytochrome P450IIE1 and cytochrome P450IIIA

1 reference

12 December 2020

Effect of neurotrauma on hepatic drug clearance

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12 December 2020

The influence of dose and ethnic origins on the pharmacokinetics of nifedipine

1 reference

12 December 2020

Relationship between the metabolism of antipyrine, hexobarbitone and theophylline in man as assessed by a 'cocktail' approach

1 reference

12 December 2020

The association of age and frailty with the pharmacokinetics and pharmacodynamics of metoclopramide

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12 December 2020

Methylprednisolone pharmacokinetics, cortisol response, and adverse effects in black and white renal transplant recipients

1 reference

12 December 2020

Racial differences in drug response. Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites

1 reference

12 December 2020

Impaired enzyme induction by rifampicin in the elderly

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12 December 2020

The effects of age and liver disease on the disposition and elimination of diazepam in adult man

1 reference

12 December 2020

Differing effect of atropine on heart rate in Chinese and white subjects

1 reference

12 December 2020

Inhibition of antipyrine metabolism by interferon

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12 December 2020

Inhibition of theophylline metabolism by interferon

1 reference

12 December 2020

Low activity of dapsone N-hydroxylation as a susceptibility risk factor in aggressive bladder cancer

1 reference

12 December 2020

Effect of fasting and obesity in humans on the 6-hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity.

1 reference

12 December 2020

Torsades de pointes occurring in association with terfenadine use

1 reference

12 December 2020

Polymorphic hydroxylation of Debrisoquine in man.

1 reference

12 December 2020

Bladder cancer recurrence and its association with cytochrome P-450IID6 activity

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12 December 2020

First-pass metabolism of cyclosporin by the gut

1 reference

12 December 2020

Reduced induction of drug metabolism in the elderly

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12 December 2020

Effects of ketoconazole on the polymorphic 4-hydroxylations of S-mephenytoin and debrisoquine

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12 December 2020

Quinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation

1 reference

12 December 2020

Antipyrine metabolism in man: influence of age, alcohol, caffeine, and smoking

1 reference

12 December 2020

Comparison of levels of several human microsomal cytochrome P-450 enzymes and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples

1 reference

12 December 2020

Plasma aspirin esterase activity in elderly patients undergoing elective hip replacement and with fractured neck of femur

1 reference

12 December 2020

Lack of influence of cigarette smoking on triazolam pharmacokinetics

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12 December 2020

Antipyrine disposition and liver size in the elderly

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12 December 2020

Divergent effects of different enzyme-inducing agents on endogenous and exogenous testosterone

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12 December 2020

Age and the Rate of Induction of Aryl Hydrocarbon Hydroxylase in Isolated Peripheral Blood Monocytes

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12 December 2020

Altered distribution of debrisoquine oxidation phenotypes in patients with systemic lupus erythematosus

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12 December 2020

Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease

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12 December 2020

Who are the frail elderly?

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12 December 2020

The Relationship between Age and Cutaneous Aryl Hydrocarbon Hydroxylase (AHH) Activity

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12 December 2020

The association of age with the induction of drug-metabolizing enzymes in human monocytes

1 reference

12 December 2020

Effect of age on single- and multiple-dose pharmacokinetics of erythromycin

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12 December 2020

Hepatic cytochrome P-4503A (CYP3A) activity in the elderly

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12 December 2020

Aging and drug interactions. III. Individual and combined effects of cimetidine and cimetidine and ciprofloxacin on theophylline metabolism in healthy male and female nonsmokers.

1 reference

12 December 2020

Ethnic differences in the pharmacokinetics of oral nifedipine

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12 December 2020

Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

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12 December 2020

Mutant debrisoquine hydroxylation genes in Parkinson's disease

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12 December 2020

Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men

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12 December 2020

Small Intestinal Cytochromes P450

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12 December 2020

Specific and dose-dependent enzyme induction by omeprazole in human beings.

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12 December 2020

Factors affecting the absolute bioavailability of nifedipine

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12 December 2020

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

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12 December 2020

10.2165/00003088-199733040-00005

Identifiers

DOI

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Dimensions Publication ID

5 October 2017

1018994712

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Fatcat ID

release_2dwznhrqu5bbjh2xlp2qmd7b3e

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2dwznhrqu5bbjh2xlp2qmd7b3e

24 November 2022

mapped directly with Wikidata item

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