(Q34742609)

4 August 2017

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title

Drug interactions with grapefruit juice. (English)

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4 August 2017

Ameer B

1

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PubMed ID

9260034

4 August 2017

Weintraub RA

series ordinal

2

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4 August 2017

1 August 1997

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Clinical Pharmacokinetics

4 August 2017

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4 August 2017

33

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4 August 2017

103-121

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4 August 2017

2

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https://scigraph.springernature.com/pub.10.2165/00003088-199733020-00003

4 August 2017

0 references

cites work

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test

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12 December 2020

Grapefruit juice: a possible source of variability in blood concentration of cyclosporin A

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12 December 2020

Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem

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12 December 2020

The fate of naringin in humans: a key to grapefruit juice-drug interactions?

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12 December 2020

Influence of diet and nutritional status on drug metabolism

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12 December 2020

CYP3A gene expression in human gut epithelium

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12 December 2020

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

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12 December 2020

Influences of diet and nutrition on clinical pharmacokinetics

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12 December 2020

Grapefruit juice-felodipine interaction: reproducibility and characterization with the extended release drug formulation.

1 reference

12 December 2020

Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin

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12 December 2020

Interaction of citrus juices with felodipine and nifedipine

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12 December 2020

The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions

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12 December 2020

Interaction between grapefruit juice and midazolam in humans.

1 reference

12 December 2020

Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram

1 reference

12 December 2020

Population variability in the pharmacokinetics of terfenadine: the case for a pseudo-polymorphism with clinical implications

1 reference

12 December 2020

In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringenin and other flavonoids

1 reference

12 December 2020

Effects of bioflavonoids on hepatic P450 activities

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12 December 2020

Effect of grapefruit juice on blood cyclosporin concentration

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12 December 2020

The influence of food on the absorption and metabolism of drugs: an update

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12 December 2020

Acute effects of drinking grapefruit juice on the pharmacokinetics and dynamics of felodipine--and its potential clinical relevance

1 reference

12 December 2020

The effect of vehicle on the oral absorption of cyclosporin.

1 reference

12 December 2020

Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase

1 reference

12 December 2020

Effect of age and gender on the activity of human hepatic CYP3A

1 reference

12 December 2020

Rat small intestinal cytochromes P450 probed by warfarin metabolism

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12 December 2020

Influence of food and diet on gastrointestinal drug absorption: a review

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12 December 2020

Grapefruit juice does not enhance the effects of midazolam and triazolam in man.

1 reference

12 December 2020

Extrahepatic metabolism of drugs in humans

1 reference

12 December 2020

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

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12 December 2020

The effect of grapefruit juice on cyclosporine and prednisone metabolism in transplant patients

1 reference

12 December 2020

Influence of grapefruit juice on caffeine pharmacokinetics and pharmacodynamics

1 reference

12 December 2020

Grapefruit juice alters the systemic bioavailability and cardiac repolarization of terfenadine in poor metabolizers of terfenadine

1 reference

12 December 2020

Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects

1 reference

12 December 2020

First-pass metabolism of midazolam by the human intestine.

1 reference

12 December 2020

Inhibition of 17β-estradiol metabolism by grapefruit juice in ovariectomized women

1 reference

12 December 2020

The erythromycin breath test predicts the clearance of midazolam.

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12 December 2020

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

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12 December 2020

Pharmacogenetics in clinical pharmacology and toxicology.

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12 December 2020

Comparison of the effects of various flavonoids on ethoxycoumarin deethylase activity of rat intestinal and hepatic microsomes

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12 December 2020

Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans

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12 December 2020

Effect of grapefruit juice on the pharmacokinetics of amlodipine in healthy volunteers

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12 December 2020

Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice.

1 reference

12 December 2020

Cytochrome P450 of small intestinal epithelial cells. Immunochemical characterization of the increase in cytochrome P450 caused by phenobarbital

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12 December 2020

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine

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12 December 2020

Clinical importance of hepatic cytochrome P450 in drug metabolism

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12 December 2020

Grapefruit juice and drugs. How significant is the interaction?

1 reference

12 December 2020

In vitro inhibition of midazolam and quinidine metabolism by flavonoids.

1 reference

12 December 2020

Disposition of intravenous and oral cyclosporine after administration with grapefruit juice

1 reference

12 December 2020

Lacking effect of grapefruit juice on theophylline pharmacokinetics

1 reference

12 December 2020

Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability

1 reference

12 December 2020

Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man.

1 reference

12 December 2020

Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals

1 reference

12 December 2020

Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics

1 reference

12 December 2020

Influence of chronic ingestion of grapefruit juice on steady-state blood concentrations of cyclosporine A in renal transplant patients with stable graft function

1 reference

12 December 2020

Flavanone absorption after naringin, hesperidin, and citrus administration

1 reference

12 December 2020

Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice

1 reference

12 December 2020

Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17 beta-estradiol

1 reference

12 December 2020

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

1 reference

12 December 2020

Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice

1 reference

12 December 2020

Influence of Food on the Bioavailability of Drugs

1 reference

12 December 2020

Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue

1 reference

12 December 2020

Inhibition of dihydropyridine metabolism in rat and human liver microsomes by flavonoids found in grapefruit juice

1 reference

12 December 2020

Erythromycin-felodipine interaction: Magnitude, mechanism, and comparison with grapefruit juice*

1 reference

12 December 2020

Lack of effect of grapefruit juice on diltiazem bioavailability in normal subjects

1 reference

12 December 2020

Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers

1 reference

12 December 2020

Trough concentrations of cyclosporine in blood following administration with grapefruit juice

1 reference

12 December 2020

Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression

1 reference

12 December 2020

Factors affecting the absolute bioavailability of nifedipine

1 reference

12 December 2020

10.2165/00003088-199733020-00003

Identifiers

DOI

1 reference

PubMed ID

9260034

Dimensions Publication ID

4 August 2017

0 references

1 reference

PubMed ID

9260034