(Q41128208)

27 September 2017

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title

Influence of diet and nutritional status on drug metabolism (English)

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27 September 2017

I Walter-Sack

1

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PubMed ID

8827399

27 September 2017

U Klotz

series ordinal

2

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27 September 2017

1 July 1996

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Clinical Pharmacokinetics

27 September 2017

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27 September 2017

31

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27 September 2017

47-64

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27 September 2017

1

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https://scigraph.springernature.com/pub.10.2165/00003088-199631010-00004

27 September 2017

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Stable oral availability of sustained release propranolol when co-administered with hydralazine or food: evidence implicating substrate delivery rate as a determinant of presystemic drug interactions

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12 December 2020

Clinical pharmacokinetics of oral contraceptive steroids

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12 December 2020

Nutrition and chemical biotransformations in man

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12 December 2020

Drug metabolism in white vegetarians

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12 December 2020

Effect of subacute oral intake of the food antioxidant butylated hydroxyanisole on clinical parameters and phase-I and -II biotransformation capacity in man

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12 December 2020

Enhancement of the bioavailability of propranolol and metoprolol by food

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12 December 2020

The antipyrine test in clinical pharmacology: Conceptions and misconceptions

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12 December 2020

Lack of acute effect on lidocaine pharmacokinetics from parenteral nutrition.

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12 December 2020

The influence of nutrition on the systemic availability of drugs. Part I: Drug absorption

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12 December 2020

No effect of dose, hepatic function, or nutritional status on 5-FU clearance following continuous (5-day), 5-FU infusion

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12 December 2020

Hepatic drug clearance in children with leukemia: changes in clearance of model substrates during remission-induction therapy

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12 December 2020

Effects of dietary protein on theophylline pharmacokinetics and caffeine and aminopyrine breath tests

1 reference

12 December 2020

Effect of a high protein meal on the bioavailability of verapamil

1 reference

12 December 2020

Pathophysiological and disease-induced changes in drug distribution volume: pharmacokinetic implications

1 reference

12 December 2020

Effects of folic acid on phenytoin kinetics in healthy subjects

1 reference

12 December 2020

Effects of feeding on the systemic clearance of indocyanine green and propranolol blood concentrations and plasma binding

1 reference

12 December 2020

Concomitant food intake can increase the bioavailability of propranolol by transient inhibition of its presystemic primary conjugation.

1 reference

12 December 2020

Antipyrine as a probe for human oxidative drug metabolism: Identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation*

1 reference

12 December 2020

Pharmacokinetics of metronidazole in severely malnourished and nutritionally rehabilitated children

1 reference

12 December 2020

Effect of food on hepatic blood flow: implications in the "food effect" phenomenon

1 reference

12 December 2020

Influences of diet and nutrition on clinical pharmacokinetics

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12 December 2020

Effects of semisynthetic diets on xenobiotic metabolizing enzyme activity and morphology of small intestinal mucosa in humans

1 reference

12 December 2020

Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin

1 reference

12 December 2020

Drug oxidation in Asian vegetarians

1 reference

12 December 2020

Interaction of citrus juices with felodipine and nifedipine

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12 December 2020

Effect of vitamin C supplement on antipyrine disposition in man.

1 reference

12 December 2020

Interaction between grapefruit juice and midazolam in humans.

1 reference

12 December 2020

Inter- and intra-subject variation in the first-pass elimination of highly cleared drugs during chronic dosing. Studies with deuterated verapamil

1 reference

12 December 2020

Effects of hydralazine, nitroglycerin, and food on estimated hepatic blood flow

1 reference

12 December 2020

Warfarin resistance caused by broccoli

1 reference

12 December 2020

1 reference

12 December 2020

The effect of dietary energy and protein deficiency on drug metabolism

1 reference

12 December 2020

Concomitant food intake does enhance the bioavailability and effect of hydralazine

1 reference

12 December 2020

Influence of food on the pharmacokinetics of quinapril and its active diacid metabolite, CI-928

1 reference

12 December 2020

Enhanced phenacetin metabolism in human subjects fed charcoal-broiled beef

1 reference

12 December 2020

The gut wall metabolism of ethinyloestradiol and its contribution to the pre-systemic metabolism of ethinyloestradiol in humans

1 reference

12 December 2020

What is "fasting" drug administration? On the role of gastric motility in drug absorption

1 reference

12 December 2020

Pyridoxine reversal of L-dopa effects in Parkinsonism.

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12 December 2020

Nutrition and oxidative drug metabolism in man: relative influence of dietary lipids, carbohydrate, and protein

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12 December 2020

The influence of nutrition on the systemic availability of drugs. Part II: Drug metabolism and renal excretion

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12 December 2020

Effect of dietary protein and carbohydrate on theophylline metabolism in children

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12 December 2020

Effects of GRAS substances on pharmacologic effects of drugs

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12 December 2020

Influence of food on the bioavailability of spironolactone

1 reference

12 December 2020

Acute effects of drinking grapefruit juice on the pharmacokinetics and dynamics of felodipine--and its potential clinical relevance

1 reference

12 December 2020

High-fat meals increase the clearance of cyclosporine

1 reference

12 December 2020

Environmental effects on antipyrine half-life in man.

1 reference

12 December 2020

Stimulatory effect of brussels sprouts and cabbage on human drug metabolism

1 reference

12 December 2020

Influence of food on the bioavailability of a sustained-release verapamil preparation

1 reference

12 December 2020

Research review. Interactions between environmental chemicals and drug biotransformation in man.

1 reference

12 December 2020

Hepatic antipyrine metabolism in malnourished patients: influence of the type of malnutrition and course after nutritional rehabilitation

1 reference

12 December 2020

Extrahepatic metabolism of drugs in humans

1 reference

12 December 2020

Disposition of salicylic acid in malnourished Ethiopian children after single oral dose

1 reference

12 December 2020

A randomized study of propranolol on postprandial portal hyperemia in cirrhotic patients.

1 reference

12 December 2020

The effect of grapefruit juice on cyclosporine and prednisone metabolism in transplant patients

1 reference

12 December 2020

Influence of dietary protein and carbohydrate on phenytoin metabolism in man

1 reference

12 December 2020

The effect of individual dietary constituents on antipyrine clearance in Asian immigrants [proceedings]

1 reference

12 December 2020

Physiological and pharmacological variability in estimated hepatic blood flow in man.

1 reference

12 December 2020

Complex effects of diet on drug disposition

1 reference

12 December 2020

Modification of drug biotransformation by vitamin C in man

1 reference

12 December 2020

The effect of total parenteral nutrition on hepatic drug oxidation

1 reference

12 December 2020

Malnutrition and drugs: clinical implications.

1 reference

12 December 2020

Myocardial infarction after diet-induced warfarin resistance

1 reference

12 December 2020

The influence of food on the oral and intravenous pharmacokinetics of a high clearance drug: a study with labetalol

1 reference

12 December 2020

The influence of changes in dietary fat on the clearance of antipyrine and 4-hydroxylation of debrisoquine

1 reference

12 December 2020

Megadose vitamin C and metabolic effects of the pill.

1 reference

12 December 2020

Grapefruit juice and cimetidine inhibit stereoselective metabolism of nitrendipine in humans

1 reference

12 December 2020

Evaluation of postprandial hyperemia in superior mesenteric artery and portal vein in healthy and cirrhotic humans: an operator-blind echo-Doppler study.

1 reference

12 December 2020

The effect of nutritional factors on hepatic drug and toxicant metabolism

1 reference

12 December 2020

Effects of changing liver blood flow by exercise and food on kinetics and dynamics of saruplase.

1 reference

12 December 2020

Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice.

1 reference

12 December 2020

Effect of protein-energy malnutrition on drug metabolism in man.

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12 December 2020

Dietary regulation of cytochrome P450.

1 reference

12 December 2020

Influence of food on the bioavailability of "real" and "apparent" hydralazine from conventional and slow-release preparations.

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12 December 2020

Clinical importance of hepatic cytochrome P450 in drug metabolism

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12 December 2020

Pharmacokinetics of aspirin in African children with normal nutrition and malnutrition

1 reference

12 December 2020

Reduction of first-pass hepatic clearance of propranolol by food

1 reference

12 December 2020

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1 reference

12 December 2020

Mechanism by which hydralazine increases propranolol bioavailability

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12 December 2020

Inhibitors of chemical carcinogens.

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12 December 2020

Food and nifedipine pharmacokinetics

1 reference

12 December 2020

Analysis of polycyclic aromatic hydrocarbons in UK total diets

1 reference

12 December 2020

Antipyrine metabolism in African villagers.

1 reference

12 December 2020

Grapefruit juice and drugs. How significant is the interaction?

1 reference

12 December 2020

Interaction of ethinyloestradiol with ascorbic acid in man.

1 reference

12 December 2020

Disposition of intravenous and oral cyclosporine after administration with grapefruit juice

1 reference

12 December 2020

Clinical pharmacokinetics of anti-parkinsonian drugs

1 reference

12 December 2020

Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man.

1 reference

12 December 2020

Effect of fasting and obesity in humans on the 6-hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity.

1 reference

12 December 2020

Enhancement of hydralazine bioavailability by food

1 reference

12 December 2020

Increased clearance of propranolol and theophylline by high-protein compared with high-carbohydrate diet

1 reference

12 December 2020

The model drug approach in clinical pharmacology

1 reference

12 December 2020

Age and diet effects on drug action

1 reference

12 December 2020

Influence of Food Intake on Presystemic Clearance of Drugs

1 reference

12 December 2020

Stimulation of oxidative drug metabolism by parenteral refeeding of nutritionally depleted patients

1 reference

12 December 2020

Dietary influences on the kinetics of antipyrine and aminopyrine in human subjects

1 reference

12 December 2020

Glucuronidation of drugs. A re-evaluation of the pharmacological significance of the conjugates and modulating factors

1 reference

12 December 2020

Recent developments in hepatic drug oxidation. Implications for clinical pharmacokinetics

1 reference

12 December 2020

Folate Deficiency after Anticonvulsant Drugs: An Effect of Hepatic Enzyme Induction?

1 reference

12 December 2020

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

1 reference

12 December 2020

Interactions between nutrition, food and drugs in man.

1 reference

12 December 2020

Influence of food on the pharmacokinetics of perindopril and the time course of angiotensin-converting enzyme inhibition in serum.

1 reference

12 December 2020

Influence of dietary purines on the metabolism of allopurinol in man

1 reference

12 December 2020

Effects of protein and carbohydrate content of diet on drug conjugation

1 reference

12 December 2020

Antipyrine metabolite formation in children in the acute phase of malnutrition and after recovery

1 reference

12 December 2020

Food-induced increase in propranolol bioavailability--relationship to protein and effects on metabolites

1 reference

12 December 2020

Letter: Pyridoxine and serum concentration of phenytoin and phenobarbitone

1 reference

12 December 2020

Assessment of liver metabolic function. Clinical implications

1 reference

12 December 2020

A comparison of the effects of a macrobiotic diet and a Western diet on drug metabolism and plasma lipids in man

1 reference

12 December 2020

Interactions between nutritional factors and drug biotransformations in man

1 reference

12 December 2020

Influence of folic acid on blood-phenytoin levels

1 reference

12 December 2020

Effect of charcoal-broiled beef on phenacetin metabolism in man

1 reference

12 December 2020

Influence of Food on the Bioavailability of Drugs

1 reference

12 December 2020

Effects of parenteral nutritional regimens on oxidative drug metabolism

1 reference

12 December 2020

Disposition of single oral doses of butylated hydroxytoluene in man and rat.

1 reference

12 December 2020

Metabolic aspects of antioxidants and preservatives

1 reference

12 December 2020

Pharmacokinetics and metabolism of antipyrine (phenazone) after intravenous and oral administration.

1 reference

12 December 2020

Acetaminophen metabolism in subjects fed charcoal-broiled beef

1 reference

12 December 2020

Effect of dietary fat on the pharmacokinetics and pharmacodynamics of cyclosporine in kidney transplant recipients

1 reference

12 December 2020

Influence of food on the presystemic metabolism of drugs

1 reference

12 December 2020

Diet and cimetidine induce comparable changes in theophylline metabolism in normal subjects

1 reference

12 December 2020

Effect of charcoal-broiled beef on antipyrine and theophylline metabolism

1 reference

12 December 2020

Effect of food on lidocaine kinetics: Mechanism of food-related alteration in high intrinsic clearance drug elimination

1 reference

12 December 2020

Clinical pharmacokinetics of levodopa in parkinson's disease

1 reference

12 December 2020

Effect of brussels sprouts and cabbage on drug conjugation

1 reference

12 December 2020

Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man

1 reference

12 December 2020

Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers

1 reference

12 December 2020

Nutrient effects on drug metabolism and action in the elderly

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12 December 2020

Effect of carbohydrates on estimated hepatic blood flow

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12 December 2020

Effects of cancer disease on the metabolism of anticancer agents.

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12 December 2020

Food effects on propranolol systemic and oral clearance: support for a blood flow hypothesis

1 reference

12 December 2020

Effect of food on blood hydralazine levels and response in hypertension

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12 December 2020

Effects of parenteral amino acid nutritional regimens on oxidative and conjugative drug metabolism.

1 reference

12 December 2020

The effect of brassica vegetable consumption on caffeine metabolism in humans

1 reference

12 December 2020

The effect of ascorbic acid on the sulphate conjugation of ingested noradrenaline and dopamine

1 reference

12 December 2020

Acquired warfarin resistance and weight-reducing diet.

1 reference

12 December 2020

Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin

1 reference

12 December 2020

Theophylline plasma clearance in critically ill geriatric patients receiving total parenteral nutrition and in control patients

1 reference

12 December 2020

Health and ecological assessment of polynuclear aromatic hydrocarbons.

1 reference

12 December 2020

Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles

1 reference

12 December 2020

Regulation of drug metabolism in man by environmental factors

1 reference

12 December 2020

10.2165/00003088-199631010-00004

Identifiers

DOI

1 reference

PubMed ID

8827399

Dimensions Publication ID

27 September 2017

0 references

1 reference

PubMed ID

8827399