(Q33744382)

29 July 2017

title

Structural determinants of PERK inhibitor potency and selectivity (English)

1 reference

29 July 2017

3

1 reference

29 July 2017

Hong Wang

1

1 reference

29 July 2017

Jaime Blais

series ordinal

2

1 reference

29 July 2017

Timothy Cardozo

series ordinal

4

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29 July 2017

publication date

1 December 2010

1 reference

Chemical Biology and Drug Design

29 July 2017

published in

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29 July 2017

volume

76

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29 July 2017

issue

6

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29 July 2017

page(s)

480-495

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Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor

29 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

21 June 2018

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XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

21 June 2018

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Activating transcription factor 4 is translationally regulated by hypoxic stress

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking

21 June 2018

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Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

21 June 2018

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Structural basis for the autoinhibition of c-Abl tyrosine kinase

21 June 2018

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Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

21 June 2018

1 reference

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Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

21 June 2018

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Protein kinases as targets for anticancer agents: from inhibitors to useful drugs

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

21 June 2018

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A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

21 June 2018

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21 June 2018

1 reference

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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

21 June 2018

1 reference

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Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins

21 June 2018

1 reference

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21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058854

WHAT IF: a molecular modeling and drug design program

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058854

A novel class of inhibitors of peptide deformylase discovered through high-throughput screening and virtual ligand screening

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058854

Protein flexibility in ligand docking and virtual screening to protein kinases.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058854

Shape signatures: a new approach to computer-aided ligand- and receptor-based drug design

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058854

Tomocomd-Cardd, a novel approach for computer-aided ? rational? drug design: I. Theoretical and experimental assessment of a promising method for computational screening and in silico design of new anthelmintic compounds

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21070610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Novel therapeutic target: the PERKs of inhibiting the integrated stress response

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21070610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Do aligned sequences share the same fold?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21070610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1747-0285.2010.01048.X

1 reference

29 July 2017

1 reference

29 July 2017

1 reference