(Q30940049)

14 September 2017

Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking (English)

1 reference

14 September 2017

8

Ruben Abagyan

0 references

author name string

Matthieu Schapira

1

1 reference

14 September 2017

Bruce M Raaka

2

1 reference

14 September 2017

Sharmistha Das

3

1 reference

14 September 2017

Li Fan

4

1 reference

14 September 2017

Maxim Totrov

5

1 reference

14 September 2017

Zhiguo Zhou

6

1 reference

14 September 2017

Stephen R Wilson

7

1 reference

14 September 2017

Herbert H Samuels

9

1 reference

14 September 2017

language of work or name

English

0 references

publication date

30 May 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 September 2017

1 reference

14 September 2017

100

1 reference

14 September 2017

12

1 reference

14 September 2017

7354-7359

1 reference

describes a project that uses

14 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC165879/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Structure-based design and synthesis of a thyroid hormone receptor (TR) antagonist.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

High-throughput docking for lead generation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Physiological and molecular basis of thyroid hormone action

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Structural insights into the mode of action of a pure antiestrogen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

PPAR gamma and the treatment of insulin resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Nuclear-receptor ligands and ligand-binding domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Rational discovery of novel nuclear hormone receptor antagonists

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

NRIF3 is a novel coactivator mediating functional specificity of nuclear hormone receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Structure and specificity of nuclear receptor-coactivator interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Flexible protein-ligand docking by global energy optimization in internal coordinates.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Molecular basis of agonism and antagonism in the oestrogen receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Thyrotropin regulation by thyroid hormone in thyroid hormone receptor beta-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Thyroid hormone receptor beta is essential for development of auditory function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Molecular docking programs successfully predict the binding of a beta-lactamase inhibitory protein to TEM-1 beta-lactamase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

The molecular and genetic dissection of the retinoid signalling pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Mechanism of action and pure antiandrogenic properties of flutamide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

The steroid and thyroid hormone receptor superfamily

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

Steroid receptor family: structure and functions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165879

The nuclear receptor ligand-binding domain: structure and function

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1131854100

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1131854100

Recent advances in systemic therapy for breast cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1131854100

Homology modeling with internal coordinate mechanics: deformation zone mapping and improvements of models via conformational search

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12777627

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The glucocorticoid receptor in GH1 cells. Evidence from dense amino acid labeling and whole cell studies for an equilibrium model explaining the influence of hormone on the intracellular distribution of receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12777627

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1131854100

1 reference

14 September 2017

0 references

1 reference

14 September 2017

PubMed publication ID

12777627

1 reference