(Q33745009)

29 July 2017

title

PP2A1 binding, cell transducing and apoptotic properties of Vpr(77-92): a new functional domain of HIV-1 Vpr proteins (English)

1 reference

29 July 2017

PP2A1 Binding, Cell Transducing and Apoptotic Properties of Vpr77–92: A New Functional Domain of HIV-1 Vpr Proteins (English)

1 reference

10.1371/JOURNAL.PONE.0013760

DOI

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0013760

25 August 2024

0 references

Julien Guergnon

2

1 reference

29 July 2017

Amélie Croset

3

1 reference

29 July 2017

Xavier Cayla

4

1 reference

29 July 2017

Pierre Barthélemy Falanga

5

1 reference

29 July 2017

Jean-Hervé Colle

6

1 reference

29 July 2017

Alphonse Garcia

7

1 reference

29 July 2017

Angélique N. Godet

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21072166

25 August 2024

language of work or name

English

0 references

publication date

1 November 2010

1 reference

full work available at URL

29 July 2017

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013760&type=printable

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21072166

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21072166/pdf/?tool=EBI

25 August 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21072166

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21072166/?tool=EBI

25 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21072166

https://europepmc.org/articles/PMC2967473

25 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21072166

https://europepmc.org/articles/PMC2967473?pdf=render

25 August 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21072166

http://dx.plos.org/10.1371/journal.pone.0013760

25 August 2024

1 reference

10.1371/JOURNAL.PONE.0013760

DOI

https://api.crossref.org/works/10.1371/JOURNAL.PONE.0013760

25 August 2024

1 reference

29 July 2017

volume

5

1 reference

29 July 2017

issue

11

1 reference

29 July 2017

page(s)

e13760

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

1 November 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Human immunodeficiency virus type 1 Vpr: functions and molecular interactions

1 reference

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From promiscuity to precision: protein phosphatases get a makeover

21 June 2018

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HIV-1 Vpr: mechanisms of G2 arrest and apoptosis

21 June 2018

1 reference

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HIV-1 Vpr causes neuronal apoptosis and in vivo neurodegeneration.

21 June 2018

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Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation.

21 June 2018

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HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT

21 June 2018

1 reference

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21 June 2018

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Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro

21 June 2018

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The C-terminal domain of the HIV-1 regulatory protein Vpr adopts an antiparallel dimeric structure in solution via its leucine-zipper-like domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS

21 June 2018

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Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Mechanisms of CD4+ T lymphocyte cell death in human immunodeficiency virus infection and AIDS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

The cationic amphipathic alpha-helix of HIV-1 viral protein R (Vpr) binds to nucleic acids, permeabilizes membranes, and efficiently transfects cells.

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Lentiviral expression of HIV-1 Vpr induces apoptosis in human neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Effects of extracellular human immunodeficiency virus type 1 vpr protein in primary rat cortical cell cultures.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Genetic studies with the fission yeast Schizosaccharomyces pombe suggest involvement of wee1, ppa2, and rad24 in induction of cell cycle arrest by human immunodeficiency virus type 1 Vpr

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

In vivo protein transduction: delivery of a biologically active protein into the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

The amino-terminal region of Vpr from human immunodeficiency virus type 1 forms ion channels and kills neurons.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Mutational analysis of Vpr-induced G2 arrest, nuclear localization, and cell death in fission yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Effect of human immunodeficiency virus type 1 protein R (vpr) gene expression on basic cellular function of fission yeast Schizosaccharomyces pombe.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Neuronal number and volume alterations in the neocortex of HIV infected individuals.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Biochemical mechanism of HIV-1 Vpr function. Oligomerization mediated by the N-terminal domain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

The PR55 and PR65 Subunits of Protein Phosphatase 2A from Xenopus laevis. Molecular Cloning and Developmental Regulation of Expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Evolution of the primate lentiviruses: evidence from vpx and vpr

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2967473

Use of penetrating peptides interacting with PP1/PP2A proteins as a general approach for a drug phosphatase technology.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013760

A PKA survival pathway inhibited by DPT-PKI, a new specific cell permeable PKA inhibitor, is induced by T. annulata in parasitized B-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013760

Nuclear trafficking of macromolecules by an oligopeptide derived from Vpr of human immunodeficiency virus type-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013760

Critical implication of the (70-96) domain of human immunodeficiency virus type 1 Vpr protein in apoptosis of primary rat cortical and striatal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013760

Immunodetection of human immunodeficiency virus type 1 (HIV-1) Vpr in brain tissue of HIV-1 encephalitic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013760

Phosphatase Type 2A-dependent and -independent Pathways for ATR Phosphorylation of Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013760

Purification and properties of polycation-stimulated phosphorylase phosphatases from rabbit skeletal muscle

21 January 2018

1 reference

12 December 2020

SPOT synthesis. Epitope analysis with arrays of synthetic peptides prepared on cellulose membranes

1 reference

12 December 2020

A C-terminal domain of HIV-1 accessory protein Vpr is involved in penetration, mitochondrial dysfunction and apoptosis of human CD4+ lymphocytes

1 reference

12 December 2020

Replication-competent HIV strains infect HIV controllers despite undetectable viremia (ANRS EP36 study)

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0013760

Identifiers

DOI

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference