(Q33746412)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Melissa Doherty

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Douglas G Osborne

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Diana L Browning

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Scott A Wetzel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

5 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

published in

Journal of Immunology

1 reference

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19 January 2020

volume

184

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

3598-3608

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

19 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2843782/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality

14 July 2018

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Th1 and Th2 cells form morphologically distinct immunological synapses.

14 July 2018

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c-Cbl-mediated regulation of LAT-nucleated signaling complexes

14 July 2018

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Small GTPases and LFA-1 reciprocally modulate adhesion and signaling

14 July 2018

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14 July 2018

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14 July 2018

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GRAIL is up-regulated in CD4+ CD25+ T regulatory cells and is sufficient for conversion of T cells to a regulatory phenotype

14 July 2018

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14 July 2018

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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

14 July 2018

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Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

14 July 2018

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Secretion of IFN-gamma and not IL-2 by anergic human T cells correlates with assembly of an immature immune synapse.

14 July 2018

1 reference

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The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling

14 July 2018

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E3 ubiquitin ligases as T cell anergy factors.

14 July 2018

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Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed at the level of individual primary T cells by laser scanning cytometry

14 July 2018

1 reference

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Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice

14 July 2018

1 reference

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14 July 2018

1 reference

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TCR trafficking in resting and stimulated T cells

14 July 2018

1 reference

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Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

14 July 2018

1 reference

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A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytes

14 July 2018

1 reference

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Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization

14 July 2018

1 reference

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GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells

14 July 2018

1 reference

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Low T cell receptor expression and thermal fluctuations contribute to formation of dynamic multifocal synapses in thymocytes

14 July 2018

1 reference

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14 July 2018

1 reference

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c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors

14 July 2018

1 reference

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Transcriptional mechanisms underlying lymphocyte tolerance.

14 July 2018

1 reference

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Altered composition of the immunological synapse in an anergic, age-dependent memory T cell subset

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

The immunological synapse: a molecular machine controlling T cell activation

14 July 2018

1 reference

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Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation

14 July 2018

1 reference

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The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Three-dimensional segregation of supramolecular activation clusters in T cells

14 July 2018

1 reference

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Selective modulation of protein kinase C-theta during T-cell activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Polarity of T cell shape, motility, and sensitivity to antigen

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

T cell antigen receptor ubiquitination is a consequence of receptor-mediated tyrosine kinase activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Impaired activation and localization of LAT in anergic T cells as a consequence of a selective palmitoylation defect.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

T cells use two directionally distinct pathways for cytokine secretion.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Peptide-specific intercellular transfer of MHC class II to CD4+ T cells directly from the immunological synapse upon cellular dissociation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Resistance to CD4+CD25+ regulatory T cells and TGF-beta in Cbl-b-/- mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

The immunological synapse balances T cell receptor signaling and degradation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

The immunological synapse of CTL contains a secretory domain and membrane bridges.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

TCR transgenic mice in which usage of transgenic alpha- and beta-chains is highly dependent on the level of selecting ligand.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Antigen recognition by helper T cells elicits a sequence of distinct changes of their shape and intracellular calcium

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2843782

Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition

30 October 2018

1 reference

12 December 2020

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

1 reference

12 December 2020

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

12 December 2020

Live-cell dynamics and the role of costimulation in immunological synapse formation

1 reference

12 December 2020

Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation

1 reference

12 December 2020

In vivo anergized T cells form altered immunological synapses in vitro

1 reference

12 December 2020

Cutting Edge: Regulation of T Cell Activation Threshold by CD28 Costimulation Through Targeting Cbl-b for Ubiquitination

1 reference

12 December 2020

T lymphocyte costimulation mediated by reorganization of membrane microdomains

1 reference

12 December 2020

What is trogocytosis and what is its purpose?

1 reference

12 December 2020

Orally tolerized T cells can form conjugates with APCs but are defective in immunological synapse formation

1 reference

12 December 2020

T-cell activation is accompanied by an ubiquitination process occurring at the immunological synapse

1 reference

12 December 2020

Cbl-b regulates antigen-induced TCR down-regulation and IFN-gamma production by effector CD8 T cells without affecting functional avidity

1 reference

12 December 2020

Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response

1 reference

12 December 2020

Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0902285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207996%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

20207996

1 reference