(Q33754181)

29 July 2017

title

Mechanisms that mediate the development of fibrosis in patients with Crohn's disease (English)

1 reference

29 July 2017

0 references

Chao Li

1

1 reference

29 July 2017

John F Kuemmerle

series ordinal

2

1 reference

29 July 2017

publication date

1 July 2014

1 reference

Inflammatory Bowel Diseases

29 July 2017

published in

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29 July 2017

volume

20

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29 July 2017

issue

7

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29 July 2017

page(s)

1250-1258

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Circulating fibrocytes and Crohn's disease.

29 July 2017

cites work

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Matrix stiffness corresponding to strictured bowel induces a fibrogenic response in human colonic fibroblasts

21 June 2018

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21 June 2018

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21 June 2018

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Distinct and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlations with pathogenesis

21 June 2018

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21 June 2018

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21 June 2018

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Human colonic myofibroblasts promote expansion of CD4+ CD25high Foxp3+ regulatory T cells

21 June 2018

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N-cadherin is overexpressed in Crohn's stricture fibroblasts and promotes intestinal fibroblast migration

21 June 2018

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Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosis

21 June 2018

1 reference

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Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 June 2018

1 reference

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Mesenchymal cells of the intestinal lamina propria

21 June 2018

1 reference

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Molecular reclassification of Crohn's disease by cluster analysis of genetic variants

21 June 2018

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Endogenous IGFBP-3 regulates excess collagen expression in intestinal smooth muscle cells of Crohnʼs disease strictures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Specific differences in migratory function of myofibroblasts isolated from Crohn's disease fistulae and strictures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Amelioration of excess collagen IαI, fibrosis, and smooth muscle growth in TNBS-induced colitis in IGF-I(+/-) mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Intestinal Mesenchymal Cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

The natural history of adult Crohn's disease in population-based cohorts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Endogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohn's disease

21 June 2018

1 reference

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A new animal model of postsurgical bowel inflammation and fibrosis: the effect of commensal microflora

21 June 2018

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Regulation of TGF-beta signaling by Smad7.

21 June 2018

1 reference

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Intestinal fibrosis in IBD--a dynamic, multifactorial process

21 June 2018

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Interactions between extracellular matrix and growth factors in wound healing

21 June 2018

1 reference

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Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid-induced colorectal fibrosis

21 June 2018

1 reference

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Increased immune reactivity predicts aggressive complicating Crohn's disease in children

21 June 2018

1 reference

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21 June 2018

1 reference

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Cellular and molecular mechanisms of fibrosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease

21 June 2018

1 reference

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The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Fibrogenesis in Crohn's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Angiogenesis as a novel component of inflammatory bowel disease pathogenesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

The role of circulating fibrocytes in fibrosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Structure and function of matrix metalloproteinases and TIMPs

21 June 2018

1 reference

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NLRs join TLRs as innate sensors of pathogens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

21 June 2018

Genetic origin of IBD.

1 reference

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Medical therapy for Crohn's disease strictures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Minireview: Integral Membrane Proteins that Function Coordinately with the Insulin-Like Growth Factor I Receptor to Regulate Intracellular Signaling

21 June 2018

1 reference

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Expression and regulation of tissue inhibitor of metalloproteinase-1 and matrix metalloproteinases by intestinal myofibroblasts in inflammatory bowel disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

The comparative role of activator protein 1 and Smad factors in the regulation of Timp-1 and MMP-1 gene expression by transforming growth factor-beta 1

21 June 2018

1 reference

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IGF-I and TGF-beta1 have distinct effects on phenotype and proliferation of intestinal fibroblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Invited review: focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Collagen content and types in the intestinal strictures of Crohn's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

The interaction of SRC kinase with beta3 integrin tails: a potential therapeutic target in thrombosis and cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease after immunosuppressive treatment correlate with histological score and calprotectin values

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

IL-13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Post-transcriptional regulation of Smad7 in the gut of patients with inflammatory bowel disease.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

IGFBP-3 activates TGF-beta receptors and directly inhibits growth in human intestinal smooth muscle cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Autocrine fibronectin-induced migration of human colonic fibroblasts

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Long-term evolution of disease behavior of Crohn's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Differential expression of TGF-beta isoforms by normal and inflammatory bowel disease intestinal myofibroblasts

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

IGFBP-3 and IGFBP-5 production by human intestinal muscle: reciprocal regulation by endogenous TGF-beta1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4057349

The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study

30 October 2018

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12 December 2020

Insulin-like growth factor I and insulin-like growth factor binding protein 5 in Crohn's disease

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12 December 2020

Reduced migration of fibroblasts in inflammatory bowel disease: role of inflammatory mediators and focal adhesion kinase

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12 December 2020

Characteristics of inflammation-induced hypertrophy of rat intestinal smooth muscle cell

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12 December 2020

Matrix metalloproteinases as profibrotic factors in terminal ileum in Crohn's disease

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12 December 2020

Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis

1 reference

12 December 2020

Matrix metalloproteinases and their tissue inhibitors as prognostic indicators for diagnostic and surgical recurrence in Crohn's disease.

1 reference

12 December 2020

Fibroblast activation protein expression in Crohn's disease strictures

1 reference

12 December 2020

IGF-I and procollagen alpha1(I) are coexpressed in a subset of mesenchymal cells in active Crohn's disease

1 reference

12 December 2020

10.1097/MIB.0000000000000043

Identifiers

DOI

1 reference

release_5s3f35tmjrgrlngos7exemom64

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5s3f35tmjrgrlngos7exemom64

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4057349

1 reference

29 July 2017

1 reference