(Q33760871)

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Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.

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9 March 2020

Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release (English)

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9 March 2020

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9 March 2020

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9 March 2020

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9 March 2020

Matteo Iannacone

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9 March 2020

Omid C. Farokhzad

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9 March 2020

Robert S. Langer, Jr.

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Robert S Langer

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9 March 2020

Aleksandar F Radovic-Moreno

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Aleksandar F Radovic-Moreno

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9 March 2020

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Jinjun Shi

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9 March 2020

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Petr O Ilyinskii

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9 March 2020

Conlin P O'Neil

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9 March 2020

Erica A Browning

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9 March 2020

Lynnelle A Pittet

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9 March 2020

David H Altreuter

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9 March 2020

Frank Alexis

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9 March 2020

Lloyd P M Johnston

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9 March 2020

Takashi Kei Kishimoto

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9 March 2020

Ulrich H von Andrian

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9 March 2020

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1 March 2014

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9 March 2020

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9 March 2020

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9 March 2020

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9 March 2020

2882-2895

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9 March 2020

Adjuvants for human vaccines

1 reference

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14 July 2018

Innate immunity and adjuvants

1 reference

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14 July 2018

Immunological mechanisms of vaccination

1 reference

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14 July 2018

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

1 reference

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14 July 2018

The control of adaptive immune responses by the innate immune system

1 reference

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14 July 2018

Toll-like receptor modulators: a patent review (2006-2010).

1 reference

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14 July 2018

Progress in understanding adjuvant immunotoxicity mechanisms

1 reference

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14 July 2018

Programming the magnitude and persistence of antibody responses with innate immunity

1 reference

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14 July 2018

Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns

1 reference

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14 July 2018

Unmet needs in modern vaccinology: adjuvants to improve the immune response

1 reference

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14 July 2018

Immunostimulatory CpG oligonucleotides: Effect on gene expression and utility as vaccine adjuvants

1 reference

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14 July 2018

Currently approved prophylactic HPV vaccines

1 reference

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14 July 2018

CpG oligodeoxynucleotides as TLR9 agonists: therapeutic applications in cancer.

1 reference

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14 July 2018

Cellular immune response to cryptic epitopes during therapeutic gene transfer

1 reference

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14 July 2018

The path to a successful vaccine adjuvant--'the long and winding road'.

1 reference

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14 July 2018

The immunogenicity of CpG-antigen conjugates

1 reference

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14 July 2018

Enhancing the therapeutic efficacy of CpG oligonucleotides using biodegradable microparticles

1 reference

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14 July 2018

Synthetic TLR4-active glycolipids as vaccine adjuvants and stand-alone immunotherapeutics

1 reference

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14 July 2018

Recognition of viral single-stranded RNA by Toll-like receptors

1 reference

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14 July 2018

Effect of resiquimod 0.01% gel on lesion healing and viral shedding when applied to genital herpes lesions

1 reference

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14 July 2018

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

1 reference

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14 July 2018

Understanding respiratory syncytial virus (RSV) vaccine-enhanced disease.

1 reference

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14 July 2018

Antiinfective applications of toll-like receptor 9 agonists

1 reference

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14 July 2018

Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Oral resiquimod in chronic HCV infection: safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Vaccine adjuvants revisited

1 reference

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14 July 2018

Therapeutic potential of Toll-like receptor 9 activation

1 reference

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14 July 2018

Synthesis and characterization of PLGA nanoparticles

1 reference

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14 July 2018

Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Polylactide-co-glycolide microparticles with surface adsorbed antigens as vaccine delivery systems

1 reference

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14 July 2018

Phase 1 trial of a CpG oligodeoxynucleotide for patients with recurrent glioblastoma

1 reference

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14 July 2018

The Toll-like receptor 7 (TLR7) agonist, imiquimod, and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Controlled ring-opening polymerization of lactide and glycolide

1 reference

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14 July 2018

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

1 reference

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14 July 2018

Randomized, single-blind, placebo-controlled study of topical application of the immune response modulator resiquimod in healthy adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Intratumor CpG-Oligodeoxynucleotide Injection Induces Protective Antitumor T Cell Immunity

1 reference

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14 July 2018

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

A Toll-like receptor recognizes bacterial DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides

1 reference

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14 July 2018

CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

Immunostimulatory DNA sequences necessary for effective intradermal gene immunization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

14 July 2018

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

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14 July 2018

Targeted delivery of TLR ligands to human and mouse dendritic cells strongly enhances adjuvanticity

1 reference

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30 October 2018

Nanoparticles target distinct dendritic cell populations according to their size

1 reference

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30 October 2018

Topical resiquimod 0.01% gel decreases herpes simplex virus type 2 genital shedding: a randomized, controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

30 October 2018

Hepatitis C virus polyprotein vaccine formulations capable of inducing broad antibody and cellular immune responses

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30 October 2018

Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4059049

30 October 2018

Imiquimod and resiquimod in a mouse model: adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery

1 reference

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30 October 2018

The immune response modifier and Toll-like receptor 7 agonist S-27609 selectively induces IL-12 and TNF-alpha production in CD11c+CD11b+CD8- dendritic cells

1 reference

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30 October 2018

Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

1 reference

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30 October 2018

Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model.

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30 October 2018

Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs.

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30 October 2018

Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants.

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30 October 2018

QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immmunization in humans

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7 January 2021

Gp120-alum boosting of a Gag-Pol-Env DNA/MVA AIDS vaccine: poorer control of a pathogenic viral challenge

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7 January 2021

HIV-1 Tat-coated nanoparticles result in enhanced humoral immune responses and neutralizing antibodies compared to alum adjuvant

1 reference

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7 January 2021

Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin

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7 January 2021

Activation of dendritic cells and induction of CD4(+) T cell differentiation by aluminum-containing adjuvants

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7 January 2021

TLR-7 and -8 agonists as vaccine adjuvants

1 reference

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7 January 2021

Bacterial DNA causes septic shock

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7 January 2021

Adjuvant activities of immune response modifier R-848: comparison with CpG ODN

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7 January 2021

MPEO-PLA nanoparticles: effect of MPEO content on some of their surface properties

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7 January 2021

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

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7 January 2021

Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma

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7 January 2021

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10.1016/J.VACCINE.2014.02.027

1 reference

Europe PubMed Central

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9 March 2020

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Europe PubMed Central

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9 March 2020

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1 reference

Europe PubMed Central

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9 March 2020

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