(Q37800358)

23 August 2017

title

Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns (English)

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23 August 2017

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1

Martin F Bachmann

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23 August 2017

Gary T Jennings

2

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23 August 2017

publication date

15 October 2010

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Nature Reviews Immunology

23 August 2017

published in

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23 August 2017

volume

10

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23 August 2017

issue

11

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23 August 2017

page(s)

787-796

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https://scigraph.springernature.com/pub.10.1038/nri2868

23 August 2017

exact match

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cites work

Designing recombinant vaccines with viral properties: a rational approach to more effective vaccines

1 reference

Rational antibody-based HIV-1 vaccine design: current approaches and future directions

31 March 2020

1 reference

Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study

31 March 2020

1 reference

A vaccine against nicotine for smoking cessation: a randomized controlled trial

31 March 2020

1 reference

Recent developments of biodegradable and biocompatible materials based micro/nanoparticles for delivering macromolecular therapeutics

31 March 2020

1 reference

Virus-sized vaccine delivery systems

31 March 2020

1 reference

On natural and artificial vaccinations

31 March 2020

1 reference

Nanoparticles and microparticles as vaccine-delivery systems

31 March 2020

1 reference

Dendritic cells and the control of immunity

31 March 2020

1 reference

Both dendritic cells and macrophages can stimulate naive CD8 T cells in vivo to proliferate, develop effector function, and differentiate into memory cells.

31 March 2020

1 reference

Targeting to macrophages: role of physicochemical properties of particulate carriers--liposomes and microspheres--on the phagocytosis by macrophages.

31 March 2020

1 reference

An integrated view of humoral innate immunity: pentraxins as a paradigm

31 March 2020

1 reference

Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses.

31 March 2020

1 reference

Exploiting lymphatic transport and complement activation in nanoparticle vaccines

31 March 2020

1 reference

Heat denaturation, a simple method to improve the immunotherapeutic potential of allergens

31 March 2020

1 reference

Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages

31 March 2020

1 reference

Designing CD8+ T cell vaccines: it's not rocket science (yet).

31 March 2020

1 reference

Loading of MHC class I and II presentation pathways by exogenous antigens: a quantitative in vivo comparison

31 March 2020

1 reference

Phagocytic processing of bacterial antigens for class I MHC presentation to T cells.

31 March 2020

1 reference

Anti-tumor CD8+ T cell immunity elicited by HIV-1-based virus-like particles incorporating HPV-16 E7 protein.

31 March 2020

1 reference

Dendritic-cell trafficking to lymph nodes through lymphatic vessels

31 March 2020

1 reference

The physiology of the lymphatic system

31 March 2020

1 reference

In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles.

31 March 2020

1 reference

Lymphatic uptake and biodistribution of liposomes after subcutaneous injection. II. Influence of liposomal size, lipid compostion and lipid dose

31 March 2020

1 reference

Effective permeability of hydrophilic substances through walls of lymph vessels: roles of endothelial barrier

31 March 2020

1 reference

Studies on the permeability of lymphatic capillaries

31 March 2020

1 reference

Nanoparticles target distinct dendritic cell populations according to their size

31 March 2020

1 reference

Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels

31 March 2020

1 reference

The influence of antigen organization on B cell responsiveness

31 March 2020

1 reference

Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies

31 March 2020

1 reference

Regulation of IgG antibody responses by epitope density and CD21-mediated costimulation

31 March 2020

1 reference

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

31 March 2020

1 reference

TLR9 signaling in B cells determines class switch recombination to IgG2a

31 March 2020

1 reference

Control of B-cell responses by Toll-like receptors

31 March 2020

1 reference

BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation

31 March 2020

1 reference

Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses

31 March 2020

1 reference

The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node

31 March 2020

1 reference

Conduits mediate transport of low-molecular-weight antigen to lymph node follicles

31 March 2020

1 reference

The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles.

31 March 2020

1 reference

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

31 March 2020

1 reference

Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells.

31 March 2020

1 reference

B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node

31 March 2020

1 reference

Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells

31 March 2020

1 reference

Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes

31 March 2020

1 reference

Cell surface recycling of internalized antigen permits dendritic cell priming of B cells

31 March 2020

1 reference

Distinct roles for DC-SIGN+-dendritic cells and Langerhans cells in HIV-1 transmission

31 March 2020

1 reference

DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

31 March 2020

1 reference

The innate functions of dendritic cells in peripheral lymphoid tissues.

31 March 2020

1 reference

Plasmacytoid dendritic cells in immunity

31 March 2020

1 reference

Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases

31 March 2020

1 reference

CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo.

31 March 2020

1 reference

Differential antigen processing by dendritic cell subsets in vivo

31 March 2020

1 reference

Cutting edge: limited specialization of dendritic cell subsets for MHC class II-associated presentation of viral particles

31 March 2020

1 reference

Antigen-presentation properties of plasmacytoid dendritic cells

31 March 2020

1 reference

Size-dependent immunogenicity: therapeutic and protective properties of nano-vaccines against tumors

31 March 2020

1 reference

Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX adjuvant in women with cervical intraepithelial neoplasia

31 March 2020

1 reference

IRAP identifies an endosomal compartment required for MHC class I cross-presentation

31 March 2020

1 reference

The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells

31 March 2020

1 reference

Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza

31 March 2020

1 reference

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

31 March 2020

1 reference

Immunostimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism

31 March 2020

1 reference

Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects

31 March 2020

1 reference

Therapeutic potential of Toll-like receptor 9 activation

31 March 2020

1 reference

Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients

31 March 2020

1 reference

Neutralizing antiviral B cell responses

31 March 2020

1 reference

The relationship between antigenic structure and the requirement for thymus-derived cells in the immune response

31 March 2020

1 reference

Specific cellular stimulation in the primary immune response: a quantized model

31 March 2020

1 reference

Determinants of autoantibody induction by conjugated papillomavirus virus-like particles

31 March 2020

1 reference

Therapeutic vaccination for chronic diseases: a new class of drugs in sight

31 March 2020

1 reference

The role of complement in inflammation and adaptive immunity

31 March 2020

1 reference

Germinal center structure and function: lessons from CD19

31 March 2020

1 reference

C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

31 March 2020

1 reference

CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes

31 March 2020

1 reference

Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1

31 March 2020

1 reference

Regulation and functions of Blimp-1 in T and B lymphocytes

31 March 2020

1 reference

Control of early viral and bacterial distribution and disease by natural antibodies

31 March 2020

1 reference

On differences between immunity and immunological memory

31 March 2020

1 reference

Hepatitis B virus immunopathogenesis

31 March 2020

1 reference

T cells and viral persistence: lessons from diverse infections

31 March 2020

1 reference

Reflections on CD8 T-cell activation and memory

31 March 2020

1 reference

Duration of TCR stimulation determines costimulatory requirement of T cells

31 March 2020

1 reference

The duration of antigenic stimulation determines the fate of naive and effector T cells.

31 March 2020

1 reference

Long-lived memory CD8+ T cells are programmed by prolonged antigen exposure and low levels of cellular activation.

31 March 2020

1 reference

Antigen kinetics determines immune reactivity

31 March 2020

1 reference

Germinal centres: role in B-cell physiology and malignancy

31 March 2020

1 reference

Ontogeny of the immune response. I. The development of the follicular antigen-trapping mechanism

31 March 2020

1 reference

The maintenance and regulation of the humoral immune response: persisting antigen and the role of follicular antigen-binding dendritic cells as accessory cells

31 March 2020

1 reference

Regulation of memory antibody levels: the role of persisting antigen versus plasma cell life span

31 March 2020

1 reference

Vaccinology of poliomyelitis

31 March 2020

1 reference

Vaccine immunopotentiators of the future

31 March 2020

1 reference

Mechanism of action of licensed vaccine adjuvants

31 March 2020

1 reference

IC31, a two-component novel adjuvant mixed with a conjugate vaccine enhances protective immunity against pneumococcal disease in neonatal mice

31 March 2020

1 reference

Toll or toll-free adjuvant path toward the optimal vaccine development

31 March 2020

1 reference

Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response

31 March 2020

1 reference

Targeting CpG oligonucleotides to the lymph node by nanoparticles elicits efficient antitumoral immunity.

31 March 2020

1 reference

A fundamental role for interleukin-21 in the generation of T follicular helper cells

31 March 2020

1 reference

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

31 March 2020

1 reference

Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner

31 March 2020

1 reference

AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity

31 March 2020

1 reference

New adjuvants for human vaccines

31 March 2020

1 reference

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

31 March 2020

1 reference

Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome

31 March 2020

1 reference

Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

31 March 2020

1 reference

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity

31 March 2020

1 reference

Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity

31 March 2020

1 reference

Relationship between the strength of antigen adsorption to an aluminum-containing adjuvant and the immune response

31 March 2020

1 reference

Effect of the strength of adsorption of hepatitis B surface antigen to aluminum hydroxide adjuvant on the immune response

31 March 2020

1 reference

Origin and physiological roles of inflammation

31 March 2020

1 reference

Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

31 March 2020

1 reference

Role of aluminum-containing adjuvants in antigen internalization by dendritic cells in vitro.

31 March 2020

1 reference

Approaching the asymptote? Evolution and revolution in immunology

31 March 2020

1 reference

The effect of adjuvants and prior immunization on the rate and mode of uptake of antigen into afferent popliteal lymph from sheep

31 March 2020

1 reference

12 December 2020

Expression of complement receptors 1 and 2 on follicular dendritic cells is necessary for the generation of a strong antigen-specific IgG response.

1 reference

12 December 2020

Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules.

1 reference

12 December 2020

The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages.

1 reference

12 December 2020

Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response

1 reference

12 December 2020

Transport in lymphatic capillaries. I. Macroscopic measurements using residence time distribution theory

1 reference

12 December 2020

Immunization with recombinant protein: conditions for cytotoxic T cell and/or antibody induction

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI2868

1 reference

Dimensions Publication ID

23 August 2017

1047690272

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