(Q33765011)

English

No cardiac effects of therapeutic and supratherapeutic doses of rupatadine: results from a 'thorough QT/QTc study' performed according to ICH guidelines.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406224%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

No cardiac effects of therapeutic and supratherapeutic doses of rupatadine: results from a 'thorough QT/QTc study' performed according to ICH guidelines (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406224%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

6

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31 January 2020

Rosa Maria Antonijoan

5

object named as

Rosa M Antonijoan

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31 January 2020

Iñaki Izquierdo

2

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Iñaki Izquierdo

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31 January 2020

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Ester Donado

1

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31 January 2020

Iñaki Pérez

3

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31 January 2020

Olga García

4

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31 January 2020

Anna Solans

7

1 reference

Europe PubMed Central

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31 January 2020

Juana Peña

8

1 reference

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31 January 2020

Joel Morganroth

9

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31 January 2020

Manuel J Barbanoj

10

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31 January 2020

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publication date

1 April 2010

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31 January 2020

British Journal of Clinical Pharmacology

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31 January 2020

69

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31 January 2020

4

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31 January 2020

401-410

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406224%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

Rupatadine in allergic rhinitis and chronic urticaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: a single-dose, randomized, open-label, two-way crossover study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Lack of effects between rupatadine 10 mg and placebo on actual driving performance of healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Effect of H1 antihistamines upon the cardiovascular system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Rupatadine: pharmacological profile and its use in the treatment of allergic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Evaluation of vardenafil and sildenafil on cardiac repolarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

A definitive or thorough phase 1 QT ECG trial as a requirement for drug safety assessment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Drug induced QT prolongation and torsades de pointes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Consensus Group on New-Generation Antihistamines (CONGA): present status and recommendations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Rupatadine: a new selective histamine H1 receptor and platelet-activating factor (PAF) antagonist. A review of pharmacological profile and clinical management of allergic rhinitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

H1-antihistamines: inverse agonism, anti-inflammatory actions and cardiac effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Allergic rhinitis and its impact on asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

22 June 2018

Torsade de pointes associated with rupatadine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

Heart rhythm disturbances associated with rupatadine: a case series from the Spanish and Portuguese pharmacovigilance systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

Torsades de pointes associated with rupatadine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

Levocetirizine does not prolong the QT/QTc interval in healthy subjects: results from a thorough QT study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

Comparing the new antihistamines: the role of pharmacological parameters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

Evaluation of the cognitive, psychomotor and pharmacokinetic profiles of rupatadine, hydroxyzine and cetirizine, in combination with alcohol, in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

International Conference on Harmonisation; guidance on E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential for Non-Antiarrhythmic Drugs; availability. Notice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

Central and peripheral evaluation of rupatadine, a new antihistamine/platelet-activating factor antagonist, at different doses in healthy volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

Effects of rupatadine, a new dual antagonist of histamine and platelet-activating factor receptors, on human cardiac kv1.5 channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848413

30 October 2018

Mechanism of the cardiotoxic actions of terfenadine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406224

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2009.03599.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406224%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PMC publication ID

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Europe PubMed Central

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31 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20406224%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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