(Q33767083)

29 July 2017

title

FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells (English)

1 reference

29 July 2017

Ethan V Abel

1

1 reference

29 July 2017

Andrew E Aplin

series ordinal

2

1 reference

29 July 2017

language of work or name

English

0 references

publication date

23 March 2010

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29 July 2017

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29 July 2017

volume

70

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29 July 2017

issue

7

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29 July 2017

page(s)

2891-2900

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Targeting the RAF-MEK-ERK pathway in cancer therapy

29 July 2017

cites work

1 reference

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Efficient tumour formation by single human melanoma cells

22 June 2018

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Regulation of embryonic stem cell self-renewal and pluripotency by Foxd3

22 June 2018

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Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF.

22 June 2018

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ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

22 June 2018

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colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis

22 June 2018

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Dissection of the functional interaction between p53 and the embryonic proto-oncoprotein PAX3.

22 June 2018

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The emerging roles of forkhead box (Fox) proteins in cancer

22 June 2018

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BRAF(E600) in benign and malignant human tumours

22 June 2018

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AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in precl

22 June 2018

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Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells

22 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Cyclin D3 expression in melanoma cells is regulated by adhesion-dependent phosphatidylinositol 3-kinase signaling and contributes to G1-S progression

22 June 2018

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In control of biology: of mice, men and Foxes

22 June 2018

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B-RAF and PI-3 kinase signaling protect melanoma cells from anoikis

22 June 2018

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Stimulation of oncogenic metabotropic glutamate receptor 1 in melanoma cells activates ERK1/2 via PKCepsilon

22 June 2018

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BRAF mutation predicts sensitivity to MEK inhibition

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Foxd3 is required in the trophoblast progenitor cell lineage of the mouse embryo

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

The Brn-2 transcription factor links activated BRAF to melanoma proliferation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Mutations of the BRAF gene in human cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis

22 June 2018

1 reference

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Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

22 June 2018

1 reference

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A new mathematical model for relative quantification in real-time RT-PCR

22 June 2018

1 reference

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The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells

22 June 2018

1 reference

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WAF1, a potential mediator of p53 tumor suppression

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Mutational analysis of the human p53 gene in malignant melanoma

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

FOXD3 regulates the lineage switch between neural crest-derived glial cells and pigment cells by repressing MITF through a non-canonical mechanism

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Effectively targeting BRAF in melanoma: a formidable challenge

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

SnapShot: p53 posttranslational modifications

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Requirement for Foxd3 in the maintenance of neural crest progenitors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Mutant B-RAF mediates resistance to anoikis via Bad and Bim.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2848900

Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation

30 October 2018

1 reference

12 December 2020

Suppression of BRAF(V599E) in human melanoma abrogates transformation

1 reference

12 December 2020

Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling

1 reference

12 December 2020

Clonally cultured differentiated pigment cells can dedifferentiate and generate multipotent progenitors with self-renewing potential

1 reference

12 December 2020

10.1158/0008-5472.CAN-09-3139

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

1 reference