(Q40302263)

19 September 2017

B-RAF and PI-3 kinase signaling protect melanoma cells from anoikis (English)

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19 September 2017

Boisvert-Adamo K

1

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19 September 2017

Aplin AE

series ordinal

2

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19 September 2017

language of work or name

English

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publication date

20 March 2006

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19 September 2017

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19 September 2017

25

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19 September 2017

35

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19 September 2017

4848-4856

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209493

19 September 2017

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cites work

FGF expression allows nevus cells to survive in three-dimensional collagen gel under conditions that induce apoptosis in normal human melanocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Transforming growth factor beta1 induces apoptosis in normal melanocytes but not in nevus cells grown in type I collagen gel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Progression in cutaneous malignant melanoma is associated with distinct expression profiles: a tissue microarray-based study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Genetic epidemiology of melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Mutation of B-Raf in human choroidal melanoma cells mediates cell proliferation and transformation through the MEK/ERK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Mutations of the BRAF gene in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Disruption of epithelial cell-matrix interactions induces apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

1 reference

7 January 2021

B-RAF and melanocytic neoplasia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Anchorage-dependent ERK signaling--mechanisms and consequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

MEK kinase activity is not necessary for Raf-1 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Induction of NF-kappaB by the Akt/PKB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

B-RAF is a therapeutic target in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

1 reference

7 January 2021

The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Insulin-like growth factor binding protein 5 and apoptosis in mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

High frequency of BRAF mutations in nevi

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Analysis of the transcriptional program induced by Raf in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Fibronectin suppresses apoptosis in normal human melanocytes through an integrin-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Deregulated Akt3 activity promotes development of malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

V599EB-RAF is an oncogene in melanocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209493

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209493

1 reference

Dimensions Publication ID

19 September 2017

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1 reference