(Q33770594)

29 July 2017

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title

The hairpin ribozyme. Discovery, mechanism, and development for gene therapy (English)

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29 July 2017

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Shippy R

1

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29 July 2017

Lockner R

series ordinal

2

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29 July 2017

Farnsworth M

series ordinal

3

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29 July 2017

Hampel A

series ordinal

4

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29 July 2017

publication date

1 August 1999

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29 July 2017

published in

Molecular Biotechnology

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29 July 2017

volume

12

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29 July 2017

issue

1

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29 July 2017

page(s)

117-129

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https://scigraph.springernature.com/pub.10.1385/mb:12:1:117

29 July 2017

exact match

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cites work

Design of the hairpin ribozyme for targeting specific RNA sequences

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12 December 2020

Two autolytic processing reactions of a satellite RNA proceed with inversion of configuration

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12 December 2020

Structure and activity of the hairpin ribozyme in its natural junction conformation: effect of metal ions

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12 December 2020

Mutagenesis of the hairpin ribozyme

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12 December 2020

Ribozyme-targeted destruction of RNA associated with autosomal-dominant retinitis pigmentosa

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12 December 2020

Mutational analysis of loops 1 and 5 of the hairpin ribozyme

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12 December 2020

Hairpin ribozyme cleavage catalyzed by aminoglycoside antibiotics and the polyamine spermine in the absence of metal ions

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12 December 2020

Screening for important base identities in the hairpin ribozyme by in vitro selection for cleavage

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12 December 2020

Ribozyme-mediated inhibition of a Philadelphia chromosome-positive acute lymphoblastic leukemia cell line expressing the p190 bcr-abl oncogene.

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12 December 2020

Ribozyme mediated degradation of beta-amyloid peptide precursor mRNA in COS-7 cells

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12 December 2020

RNA catalytic properties of the minimum (-)sTRSV sequence

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12 December 2020

The influence of junction conformation on RNA cleavage by the hairpin ribozyme in its natural junction form

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12 December 2020

Gene therapy targeting cord blood-derived CD34+ cells from HIV-exposed infants: preclinical studies

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12 December 2020

A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavage

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12 December 2020

A potential therapeutic application of hairpin ribozymes: in vitro and in vivo studies of gene therapy for hepatitis C virus infection

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12 December 2020

Catalytically active geometry in the reversible circularization of 'mini-monomer' RNAs derived from the complementary strand of tobacco ringspot virus satellite RNA

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12 December 2020

Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.

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12 December 2020

Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: implications for secondary structure

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12 December 2020

Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1

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12 December 2020

Binding and cleavage of nucleic acids by the "hairpin" ribozyme

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12 December 2020

Stabilization of RNA structure by Mg ions. Specific and non-specific effects.

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12 December 2020

The hairpin ribozyme: structure, assembly and catalysis

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12 December 2020

Design and anti-HIV-1 activity of hammerhead and hairpin ribozymes containing a stable loop

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12 December 2020

An unusual pH-independent and metal-ion-independent mechanism for hairpin ribozyme catalysis

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12 December 2020

Novel guanosine requirement for catalysis by the hairpin ribozyme

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12 December 2020

Potent inhibition of CTLA-4 expression by an anti-CTLA-4 ribozyme

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12 December 2020

Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme

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12 December 2020

Modification of primary structures of hairpin ribozymes for probing active conformations

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12 December 2020

Folding of the hairpin ribozyme in its natural conformation achieves close physical proximity of the loops

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12 December 2020

Inhibition of HPV-16 E6/E7 immortalization of normal keratinocytes by hairpin ribozymes

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12 December 2020

In vitro and in vivo characterization of a second functional hairpin ribozyme against HIV-1.

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12 December 2020

In vitro selection of active hairpin ribozymes by sequential RNA-catalyzed cleavage and ligation reactions.

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12 December 2020

The sCYMV1 hairpin ribozyme: targeting rules and cleavage of heterologous RNA.

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12 December 2020

Analysis of hairpin ribozyme base mutations in loops 2 and 4 and their effects on cis-cleavage in vitro

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12 December 2020

'Hairpin' catalytic RNA model: evidence for helices and sequence requirement for substrate RNA.

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12 December 2020

A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1

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12 December 2020

Metal ions play a passive role in the hairpin ribozyme catalysed reaction

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12 December 2020

The hairpin ribozyme: discovery, two-dimensional model, and development for gene therapy

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12 December 2020

Multigene antiviral vectors inhibit diverse human immunodeficiency virus type 1 clades

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12 December 2020

Computer analysis of the conservation and uniqueness of ribozyme-targeted HIV sequences

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12 December 2020

Two sequences participating in the autolytic processing of satellite tobacco ringspot virus complementary RNA

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12 December 2020

Satellite tobacco ringspot virus RNA: biological activity of DNA clones and their in vitro transcripts

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12 December 2020

Nucleotide sequence and newly formed phosphodiester bond of spontaneously ligated satellite tobacco ringspot virus RNA.

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12 December 2020

Sequences required for self-catalysed cleavage of the satellite RNA of tobacco ringspot virus

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12 December 2020

Kinetics and thermodynamics of intermolecular catalysis by hairpin ribozymes

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12 December 2020

RNA mediated formation of a phosphorothioate diester bond.

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12 December 2020

Expression of ribozymes in gene transfer systems to modulate target RNA levels

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12 December 2020

Intracellular immunization of rhesus CD34+ hematopoietic progenitor cells with a hairpin ribozyme protects T cells and macrophages from simian immunodeficiency virus infection

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12 December 2020

Gene therapy targeting peripheral blood CD34+ hematopoietic stem cells of HIV-infected individuals

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12 December 2020

Solution structure of an unusually stable RNA hairpin, 5GGAC(UUCG)GUCC

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12 December 2020

Purine functional groups in essential residues of the hairpin ribozyme required for catalytic cleavage of RNA

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12 December 2020

Catalytic properties of hairpin ribozymes derived from Chicory yellow mottle virus and arabis mosaic virus satellite RNAs

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12 December 2020

Intracellular application of hairpin ribozyme genes against hepatitis B virus

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12 December 2020

Metallobiochemistry of RNA. Co(NH3)6(3+) as a probe for Mg2+(aq) binding sites

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12 December 2020

Substrate selection rules for the hairpin ribozyme determined by in vitro selection, mutation, and analysis of mismatched substrates.

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12 December 2020

Enhanced folding of hairpin ribozymes with replaced domains

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12 December 2020

Identifiers

DOI

10.1385/MB:12:1:117

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Dimensions Publication ID

29 July 2017

1043337804

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