(Q33771224)

29 July 2017

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title

Neurotoxic and synaptic effects of okadaic acid, an inhibitor of protein phosphatases (English)

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ORCID Public Data File 2021

29 July 2017

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author name string

Tapia R

series ordinal

1

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29 July 2017

Peña F

series ordinal

2

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29 July 2017

Arias C

series ordinal

3

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29 July 2017

publication date

1 November 1999

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29 July 2017

published in

Neurochemical Research

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29 July 2017

volume

24

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29 July 2017

issue

11

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29 July 2017

page(s)

1423-1430

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Role of protein phosphorylation in neuronal signal transduction

29 July 2017

cites work

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12 December 2020

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

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12 December 2020

Phosphorylation of tau, Abeta-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A.

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12 December 2020

Modulation of ion channels by protein phosphorylation and dephosphorylation

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12 December 2020

The absence of a major Ca2+ signaling pathway in GABAergic neurons of the hippocampus

1 reference

12 December 2020

Intracellular messengers in the generation and degeneration of hippocampal neuroarchitecture

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12 December 2020

Suppression of a Ca2+ current by NMDA and intracellular Ca2+ in acutely isolated hippocampal neurons

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12 December 2020

The protein phosphatase inhibitor okadaic acid increases axonal neurofilaments and neurite caliber, and decreases axonal microtubules in NB2a/d1 cells.

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12 December 2020

The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells

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12 December 2020

Neuronal damage and MAP2 changes induced by the glutamate transport inhibitor dihydrokainate and by kainate in rat hippocampus in vivo

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12 December 2020

Study on the possible involvement of protein kinases in the modulation of brain presynaptic sodium channels; comparison with calcium channels

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12 December 2020

The role of protein phosphatases in synaptic transmission, plasticity and neuronal development

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12 December 2020

Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices

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12 December 2020

Acute or chronic administration of okadaic acid to rats induces brain damage rather than Alzheimer-like neuropathology

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12 December 2020

Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.

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12 December 2020

p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]

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12 December 2020

Okadaic acid disrupts clusters of synaptic vesicles in frog motor nerve terminals

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12 December 2020

Protein tyrosine phosphorylation: implications for synaptic function

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12 December 2020

Excitatory synaptic transmission in neostriatal neurons: regulation by cyclic AMP-dependent mechanisms

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12 December 2020

Increased synthesis and accumulation of heat shock 70 proteins in Alzheimer's disease

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12 December 2020

Phosphorylation characteristics of the A68 protein in Alzheimer's disease

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12 December 2020

Okadaic acid: a new probe for the study of cellular regulation

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12 December 2020

Protein phosphatase inhibitor okadaic acid enhances transmitter release at neuromuscular junctions

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12 December 2020

Phosphorylation of paired helical filament tau in Alzheimer's disease neurofibrillary lesions: focusing on phosphatases

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12 December 2020

Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin.

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12 December 2020

Evidence for the involvement of protein kinase C in neurodegenerative changes in cultured human cortical neurons

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12 December 2020

Correlation between seizure intensity and stress protein expression after limbic epilepsy in the rat brain

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12 December 2020

Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcmeurin and phosphatase-2A

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12 December 2020

Protein phosphorylation and neuronal function.

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12 December 2020

Dephosphorylation of microtubule proteins by brain protein phosphatases 1 and 2A, and its effect on microtubule assembly

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12 December 2020

Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids

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12 December 2020

Phosphatases modulate transmission and serotonin facilitation at synapses: studies with the inhibitor okadaic acid.

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12 December 2020

The inducible 70,000 molecular/weight heat shock protein is expressed in the degenerating dentate hilus and piriform cortex after systemic administration of kainic acid in the rat.

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12 December 2020

Expression of protein phosphatases (PP-1, PP-2A, PP-2B and PTP-1B) and protein kinases (MAP kinase and P34cdc2) in the hippocampus of patients with Alzheimer disease and normal aged individuals.

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12 December 2020

Kainic acid-induced heat shock protein-70, mRNA and protein expression is inhibited by MK-801 in certain rat brain regions

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12 December 2020

Regulation of stimulus-dependent hippocampal acetylcholine release by okadaic acid-sensitive phosphoprotein phosphatases

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12 December 2020

Paired helical filament-like phosphorylation of tau, deposition of beta/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A

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12 December 2020

Okadaic acid, a protein phosphatase inhibitor, inhibits nerve growth factor-directed neurite outgrowth in PC12 cells

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12 December 2020

Synaptosomal amino acid release: effect of inhibiting protein phosphatases with okadaic acid

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12 December 2020

Phosphoprotein phosphatase activities in Alzheimer disease brain

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12 December 2020

Protein phosphatase inhibitors induce modification of synapse structure and tau hyperphosphorylation in cultured rat hippocampal neurons.

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12 December 2020

Expression of heat shock proteins in Alzheimer's disease

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12 December 2020

In vivo phosphorylation in the rat basal nucleus induces PHF-like and APP immunoreactivity

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12 December 2020

Modulation of the voltage-gated sodium current in rat striatal neurons by DARPP-32, an inhibitor of protein phosphatase

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12 December 2020

Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A.

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12 December 2020

The protein phosphatase inhibitor okadaic acid induces heat shock protein expression and neurodegeneration in rat hippocampus in vivo

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12 December 2020

Increased expression of mRNA encoding calbindin-D28K, the glucose-regulated proteins, or the 72 kDa heat-shock protein in three models of acute CNS injury

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12 December 2020

Regulation of NMDA channel function by endogenous Ca(2+)-dependent phosphatase

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12 December 2020

Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP.

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12 December 2020

Modulation of human glutamate transporter activity by phorbol ester

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12 December 2020

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

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12 December 2020

Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.

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12 December 2020

Cyclic GMP-dependent protein kinase and cellular signaling in the nervous system

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12 December 2020

Protein kinase C modulates calcium channels in isolated presynaptic nerve terminals of rat hippocampus

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12 December 2020

Roles for protein phosphorylation in synaptic transmission

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12 December 2020

Inhibition of protein phosphatases induces IGF-1-blocked neurotrophin-insensitive neuronal apoptosis.

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12 December 2020

Protein phosphorylation and dephosphorylation in mammalian central nervous system.

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12 December 2020

Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons.

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12 December 2020

Synaptic vesicle movements monitored by fluorescence recovery after photobleaching in nerve terminals stained with FM1-43.

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12 December 2020

The marine toxin okadaic acid is a potent neurotoxin for cultured cerebellar neurons.

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12 December 2020

Heat shock protein expression in vulnerable cells of the rat hippocampus as an indicator of excitation-induced neuronal stress

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12 December 2020

The phosphatase inhibitor, okadaic acid, increases peptide release from rat sensory neurons in culture

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12 December 2020

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

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12 December 2020

Protein kinase C activators decrease dopamine uptake into striatal synaptosomes

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12 December 2020

Modulation of AMPA/kainate receptors in cultured murine hippocampal neurones by protein kinase C.

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12 December 2020

Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death

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12 December 2020

Enhancement by muscarinic agonists of a high voltage-activated Ca2+ current via phosphorylation in a snail neuron

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12 December 2020

Okadaic acid induces the rapid and reversible disruption of the neurofilament network in rat dorsal root ganglion neurons

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12 December 2020

Okadaic acid induces early changes in microtubule-associated protein 2 and tau phosphorylation prior to neurodegeneration in cultured cortical neurons.

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12 December 2020

Microtubule-associated protein tau. A component of Alzheimer paired helical filaments

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12 December 2020

Protein kinases in the brain

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12 December 2020

Differential intracellular regulation of cortical GABA(A) and spinal glycine receptors in cultured neurons

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12 December 2020

Using okadaic acid as a tool for the in vivo induction of hyperphosphorylated tau.

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12 December 2020

Interaction of convergent pathways that inhibit N-type calcium currents in sensory neurons

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12 December 2020

Hippocampal damage and cytoskeletal disruption resulting from impaired energy metabolism. Implications for Alzheimer disease.

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12 December 2020

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil.

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12 December 2020

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

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12 December 2020

Neuromodulators enhance transmitter release by two separate mechanisms at the inhibitor of crayfish opener muscle

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12 December 2020

The role of calcium in capsaicin-induced desensitization in rat cultured dorsal root ganglion neurons

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12 December 2020

Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes

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12 December 2020

A role for protein kinases and phosphatases in the Ca(2+)-induced enhancement of hippocampal AMPA receptor-mediated synaptic responses.

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12 December 2020

Protein kinase C activation attenuates N-methyl-D-aspartate-induced increases in intracellular calcium in cerebellar granule cells

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12 December 2020

Phosphorylation and regulation of antidepressant-sensitive serotonin transporters

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12 December 2020

Identifiers

DOI

10.1023/A:1022588808260

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Dimensions Publication ID

29 July 2017

1042188914

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