(Q48395929)

English

Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.

scientific article published in September 1998

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/9736650

Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

author name string

E Rundén

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

P O Seglen

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

F M Haug

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

T Wieloch

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

M Shamloo

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 September 1998

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/9736650

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

7296-7305

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

Protein phosphatase inhibitors induce modification of synapse structure and tau hyperphosphorylation in cultured rat hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tyrosine phosphorylation prevents delayed neuronal death following cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of phosphoprotein phosphatases 1 and 2A cause activation of a 53 kDa protein kinase accompanying the apoptotic response of breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dementia after ischemic stroke: a population-based study in Rochester, Minnesota (1960-1984)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis: Bcl-2-related proteins get connected

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of ser/thr phosphatases 1 and 2A induce apoptosis in pituitary GH3 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KT5926, a potent and selective inhibitor of myosin light chain kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vicious cycle involving Na+ channels, glutamate release, and NMDA receptors mediates delayed neurodegeneration through nitric oxide formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent Translocation of Ca2+/Calmodulin-Dependent Protein Kinase II to Synaptic Junctions in the Vulnerable Hippocampal CA1 Region Following Transient Ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain infarction and the clinical expression of Alzheimer disease. The Nun Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that MAP (mitogen-activated protein) kinase activation may be a necessary but not sufficient signal for a restricted subset of responses in IL-1-treated epidermoid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of protein phosphatases induces IGF-1-blocked neurotrophin-insensitive neuronal apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of mitogen-activated protein kinases by nitric oxide-related species

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule assembly competence analysis of freshly-biopsied human tau, dephosphorylated tau, and Alzheimer tau.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organotypic cultures of neural tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted beta-APP stimulates MAP kinase and phosphorylation of tau in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-specific regulation of Alzheimer-like tau phosphorylation in living neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the cytokeratin cytoskeleton and inhibition of hepatocytic autophagy by okadaic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of biological activity of Alzheimer abnormally phosphorylated tau by dephosphorylation with protein phosphatase-2A, -2B and -1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular signal transduction in the postischemic brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine protein kinase activity in renal brush-border membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen-activated protein kinase translocates to the nucleus during ischaemia and is activated during reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis of human myeloid leukemia cells induced by an inhibitor of protein phosphatases (okadaic acid) is prevented by Bcl-2 and Bcl-X(L)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal neurons predisposed to neurofibrillary tangle formation are enriched in type II calcium/calmodulin-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations of Ca2+/calmodulin-dependent protein kinase II and its messenger RNA in the rat hippocampus following normo- and hypothermic ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of hepatocytic autophagy by okadaic acid and other protein phosphatase inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Okadaic acid induces hyperphosphorylated forms of tau protein in human brain slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of protein kinases and phosphatases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A beta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient ischemia differentially increases tyrosine phosphorylation of NMDA receptor subunits 2A and 2B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection by naringin and some other flavonoids of hepatocytic autophagy and endocytosis against inhibition by okadaic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced in neuronal cultures by either the phosphatase inhibitor okadaic acid or the kinase inhibitor staurosporine is attenuated by isoquinolinesulfonamides H-7, H-8, and H-9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective action of isoquinolinesulfonamides in in vitro models of neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of microtubule-associated protein kinase after transient ischemia in the gerbil brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathological phosphorylation causes neuronal death: effect of okadaic acid in primary culture of cerebellar granule cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: immunogold evidence from hippocampal slice cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in tau immunostaining in the rat hippocampus following transient cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of protein phosphatases (PP-1, PP-2A, PP-2B and PTP-1B) and protein kinases (MAP kinase and P34cdc2) in the hippocampus of patients with Alzheimer disease and normal aged individuals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ dephosphorylation of tau by protein phosphatase 2A and 2B in fetal rat primary cultured neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation and activation of mitogen-activated protein kinase in the rat brain following transient cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time Course of the Translocation and Inhibition of Protein kinase C During Complete Cerebral Ischemia in the Rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide signaling in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau phosphorylation in brain slices: pharmacological evidence for convergent effects of protein phosphatases on tau and mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin and mitochondrial function in glutamate-induced neuronal cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific inhibition of cyclic AMP-dependent protein kinase by warangalone and robustic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MAPK signaling cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential sensitivity of normal and H-ras oncogene-transformed rat kidney epithelial cells to okadaic acid-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure and biological activities of the widely used protein kinase inhibitor, H7, differ depending on the commercial source

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression and subcellular translocation of the mitogen activated protein kinase kinase and mitogen-activated protein kinase in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://pubmed.ncbi.nlm.nih.gov/9736650

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-18-07296.1998

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6793243&resulttype=core&format=json

12 May 2020

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