(Q33771832)

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Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species

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scholarly article

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Europe PubMed Central

29 July 2017

Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived species (English)

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Europe PubMed Central

29 July 2017

5

object named as

Louis J Ignarro

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Europe PubMed Central

29 July 2017

author name string

Jon M Fukuto

1

1 reference

Europe PubMed Central

29 July 2017

Samantha J Carrington

2

1 reference

Europe PubMed Central

29 July 2017

Dean J Tantillo

3

1 reference

Europe PubMed Central

29 July 2017

Jason G Harrison

4

1 reference

Europe PubMed Central

29 July 2017

Bruce A Freeman

6

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Europe PubMed Central

29 July 2017

Andrew Chen

7

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Europe PubMed Central

29 July 2017

David A Wink

8

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Europe PubMed Central

29 July 2017

publication date

9 February 2012

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Europe PubMed Central

29 July 2017

Chemical Research in Toxicology

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Europe PubMed Central

29 July 2017

25

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Europe PubMed Central

29 July 2017

4

1 reference

Europe PubMed Central

29 July 2017

769-793

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Europe PubMed Central

29 July 2017

The reaction of H(2)S with oxidized thiols: generation of persulfides and implications to H(2)S biology.

1 reference

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Electronic structure of heme-nitrosyls and its significance for nitric oxide reactivity, sensing, transport, and toxicity in biological systems

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Singlet oxygen: there is indeed something new under the sun.

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H2S signals through protein S-sulfhydration

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Hydrogen sulfide increases hypoxia-inducible factor-1 activity independently of von Hippel-Lindau tumor suppressor-1 in C. elegans

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Nitric oxide, cytochrome C oxidase, and the cellular response to hypoxia.

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The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols.

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The millisecond intermediate in the reaction of nitric oxide with oxymyoglobin is an iron(III)--nitrato complex, not a peroxynitrite

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Photodynamic therapy (PDT): a short review on cellular mechanisms and cancer research applications for PDT.

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Regulation of oxygen homeostasis by hypoxia-inducible factor 1.

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Singlet oxygen in plants: production, detoxification and signaling

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Quantification of intermediates formed during the reduction of nitrite by deoxyhemoglobin

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Chemical biology of peroxynitrite: kinetics, diffusion, and radicals.

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Nervous control of circulation--the role of gasotransmitters, NO, CO, and H2S.

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Nitrite reductase activity of cytochrome c

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The new chemical biology of nitrite reactions with hemoglobin: R-state catalysis, oxidative denitrosylation, and nitrite reductase/anhydrase

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The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal.

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Carbon monoxide-dependent energy metabolism in anaerobic bacteria and archaea

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H(2)S and HS(-) donor NaHS releases nitric oxide from nitrosothiols, metal nitrosyl complex, brain homogenate and murine L1210 leukaemia cells.

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The chemical biology of nitric oxide: implications in cellular signaling

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Interactive endogenous small molecule (gaseous) signaling: implications for teratogenesis

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An overview of the biological significance of endogenous gases: new roles for old molecules

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Mechanisms of hypoxic signal transduction regulated by reactive nitrogen species

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Regulation of HIF-1alpha stability through S-nitrosylation

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Nitric oxide and superoxide: interference with hypoxic signaling

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Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning

1 reference

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Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress

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The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO

1 reference

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Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.

1 reference

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4 July 2018

Nitric oxide regulation of mitochondrial oxygen consumption I: cellular physiology.

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4 July 2018

Inhibition of cellular respiration by endogenously produced carbon monoxide

1 reference

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Hydrogen peroxide: a signaling messenger

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4 July 2018

Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1alpha stabilization

1 reference

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Free radical biology and medicine: it's a gas, man!

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Trafficking in persulfides: delivering sulfur in biosynthetic pathways

1 reference

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Nitric oxide signaling: no longer simply on or off.

1 reference

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Oxygen sensing in the body

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4 July 2018

1 reference

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H2S induces a suspended animation-like state in mice

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Protein S-nitrosylation: purview and parameters

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The reaction between nitrite and hemoglobin: the role of nitrite in hemoglobin-mediated hypoxic vasodilation

1 reference

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Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein

1 reference

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Hydroxylation of HIF-1: oxygen sensing at the molecular level

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The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'?

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Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers

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Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide.

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HIF hydroxylation and cellular oxygen sensing

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Reactivity of dioxygen-copper systems

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Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

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Oxidation and nitrosation of thiols at low micromolar exposure to nitric oxide. Evidence for a free radical mechanism.

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4 July 2018

HIF-1 alpha protein as a target for S-nitrosation

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A novel enhancing mechanism for hydrogen sulfide-producing activity of cystathionine beta-synthase

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The reduction potential of nitric oxide (NO) and its importance to NO biochemistry.

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Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide

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Biological chemistry of carbon monoxide

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Heme-based sensors: theoretical modeling of heme-ligand-protein interactions

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On the acidity and reactivity of HNO in aqueous solution and biological systems

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4 July 2018

Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite

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Iron-sulfur proteins: ancient structures, still full of surprises

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4 July 2018

Guanylate cyclase and the .NO/cGMP signaling pathway

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4 July 2018

Nitric oxide and iron proteins

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4 July 2018

Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling

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Accelerated reaction of nitric oxide with O2 within the hydrophobic interior of biological membranes

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4 July 2018

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

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Electrostatic interactions in the active site of the N-terminal thioredoxin-like domain of protein disulfide isomerase

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The reaction of no with superoxide

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Autoxidation kinetics of aqueous nitric oxide

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The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide

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Nitric oxide rapidly scavenges tyrosine and tryptophan radicals

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Superoxide radical and superoxide dismutases

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Modification of erythrocyte enzyme activities by persulfides and methanethiol: possible regulatory role

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Oxyradical reactions: from bond-dissociation energies to reduction potentials

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Transition metals as catalysts of "autoxidation" reactions

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Reversible conversion of nitroxyl anion to nitric oxide by superoxide dismutase

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Nitric oxide: physiology, pathophysiology, and pharmacology

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4 July 2018

1 reference

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Nature of O2 and CO binding to metalloporphyrins and heme proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

4 July 2018

Hypoxia-inducible factor-1α is involved in the pro-angiogenic effect of hydrogen sulfide under hypoxic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Kinetic feasibility of nitroxyl reduction by physiological reductants and biological implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Mechanisms of peroxynitrite-mediated nitration of tyrosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Determination of hydroxyl rate constants by a high-throughput fluorimetric assay: towards a unified reactivity scale for antioxidants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

A microscopic study of the deoxyhemoglobin-catalyzed generation of nitric oxide from nitrite anion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Molecular dynamics simulation of the HOONO decomposition and the HO*/NO2* caged radical pair in water

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Theoretical investigation of nitration and nitrosation of dimethylamine by N2O4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Theoretical evidence for enhanced NO dimerization in aromatic hosts: implications for the role of the electrophile (NO)(2) in nitric oxide chemistry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Spin trapping of nitrogen dioxide and of radicals generated from nitrous acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Linkage isomerism in nitrite reduction by cytochrome cd1 nitrite reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Evidence for a proton transfer network and a required persulfide-bond-forming cysteine residue in Ni-containing carbon monoxide dehydrogenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Efficient trapping of HNO by deoxymyoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Sulfenic acid formation in human serum albumin by hydrogen peroxide and peroxynitrite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Kinetics of the reactions of nitrogen dioxide with glutathione, cysteine, and uric acid at physiological pH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Characterization of NO binding to human cystathionine beta-synthase: possible implications of the effects of CO and NO binding to the human enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Reaction between S-nitrosothiols and thiols: generation of nitroxyl (HNO) and subsequent chemistry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4061765

30 October 2018

Peroxynitrite as an alternative donor of oxygen in HIF-1alpha proline hydroxylation under low oxygen availability

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide inhibition of lipoxygenase-dependent liposome and low-density lipoprotein oxidation: termination of radical chain propagation reactions and formation of nitrogen-containing oxidized lipid derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactions of nitrogen dioxide in aqueous model systems: oxidation of tyrosine units in peptides and proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S-nitrosothiols and role of metal ions in decomposition to nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Visible light photochemical release of nitric oxide from S-nitrosoglutathione: potential photochemotherapeutic applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The resolution of active and inactive xanthine oxidase by affinity chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of porcine heart mitochondrial malate dehydrogenase by zero valence sulfur and rhodanese

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of Cu,Zn superoxide dismutase with hydrogen sulfide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Can O=NOOH undergo homolysis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate and accessory protein requirements and thermodynamics of acetyl-CoA synthesis and cleavage in Methanosarcina barkeri

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of Proteins with Sulfide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Internal electron transfer between hemes and Cu(II) bound at cysteine beta93 promotes methemoglobin reduction by carbon monoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of hydrogen sulfide toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The emerging biology of the nitrite anion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the heme and pyridoxal phosphate cofactors of human cystathionine beta-synthase reveals nonequivalent active sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of strain in the proximal ligand on the binding of nitric oxide and carbon monoxide to chelated protoheme complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein Radicals in Enzyme Catalysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamics of reactions involving nitrogen-oxygen compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for an active site persulfide residue in rabbit liver aldehyde oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reaction of nitric oxide with organic peroxyl radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrochemical studies of S-nitrosothiols

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perthiols as antioxidants: radical-scavenging and prooxidative mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the mechanism of inactivation of xanthine oxidase by cyanide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbon monoxide-driven reduction of ferric heme and heme proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22263838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photochemistry of the S-Nitroso Derivatives of Hexane-l-thiol and Hexane-l,6-dithiol

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/TX2005234

Standard Electrode Potentials and Temperature Coefficients in Water at 298.15 K

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/TX2005234

Reduction Potential of the Sulfhydryl Radical: Pulse Radiolysis and Laser Flash Photolysis Studies of the Formation and Reactions of ·SH and HSSH·-in Aqueous Solutions

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/TX2005234

Principles of structure, bonding, and reactivity for metal nitrosyl complexes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/TX2005234

Measurement of phosphorylated extracellular signal-regulated kinase 1 and 2 in an undergraduate teaching laboratory with ALPHAscreen technology.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1021/TX2005234

Identifiers

10.1021/TX2005234

1 reference

Europe PubMed Central

29 July 2017

release_xzdxsy7mvfavpoqamyfxqyogta

1 reference

https://api.fatcat.wiki/v0/release/xzdxsy7mvfavpoqamyfxqyogta

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

ResearchGate publication ID

0 references

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