(Q33775541)

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Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

apoptotic process

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prostate cancer

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

object named as

Ezra Burstein

6

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author name string

Yao Dai

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Jeffrey Desano

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Wenhua Tang

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Xiaojie Meng

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Yang Meng

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Theodore S Lawrence

7

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Europe PubMed Central

PubMed publication ID

29 July 2017

Liang Xu

8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

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publication date

10 December 2010

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Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

e14153

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

copyright license

Creative Commons Attribution 4.0 International

10 December 2010

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April 2022 Public Data File from Crossref

copyright status

0 references

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum

1 reference

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4 July 2018

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1 reference

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Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway

1 reference

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Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B.

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Celastrol synergistically enhances temozolomide cytotoxicity in melanoma cells

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A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB.

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Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa

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Bortezomib in the front-line treatment of multiple myeloma

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Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.

1 reference

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A pivotal role for Mcl-1 in Bortezomib-induced apoptosis

1 reference

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Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma

1 reference

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Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation

1 reference

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Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA.

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4 July 2018

NF-kappaB activation by double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000808

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Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000808

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Mcl-1: a highly regulated cell death and survival controller

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000808

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Down-regulating constitutive activation of the NF-kappaB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis.

1 reference

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Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL.

1 reference

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Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

1 reference

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Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).

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Bortezomib as a potential treatment for prostate cancer

1 reference

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Lineage relationship between LNCaP and LNCaP-derived prostate cancer cell lines

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Shaping the nuclear action of NF-kappaB

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The proteasome: a suitable antineoplastic target

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NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon?

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Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000808

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Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts

1 reference

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1 reference

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The role of IKK in constitutive activation of NF-kappaB transcription factor in prostate carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21170316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unraveling MCL-1 degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21170316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21170316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid

1 reference

https://pubmed.ncbi.nlm.nih.gov/21170316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0014153

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2010PLoSO...514153D

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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