(Q33515420)

27 July 2017

A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB. (English)

1 reference

27 July 2017

1 reference

1 reference

1 reference

Yao Dai

1

1 reference

27 July 2017

Meilan Liu

2

1 reference

27 July 2017

Wenhua Tang

3

1 reference

27 July 2017

Yongming Li

4

1 reference

27 July 2017

Jiqin Lian

5

1 reference

27 July 2017

Theodore S Lawrence

6

1 reference

27 July 2017

Liang Xu

7

1 reference

27 July 2017

language of work or name

English

0 references

publication date

6 November 2009

1 reference

27 July 2017

1 reference

27 July 2017

9

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27 July 2017

392

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2407-9-392

27 July 2017

0 references

cites work

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Celastrol potentiates radiotherapy by impairment of DNA damage processing in human prostate cancer

21 June 2018

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Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis.

21 June 2018

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Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres

21 June 2018

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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 June 2018

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21 June 2018

IAPs: what's in a name?

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TRAIL and cancer therapy.

21 June 2018

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A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling

21 June 2018

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Transfection of Smac/DIABLO sensitizes drug-resistant tumor cells to TRAIL or paclitaxel-induced apoptosis in vitro

21 June 2018

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IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

21 June 2018

1 reference

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IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

21 June 2018

1 reference

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Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

21 June 2018

1 reference

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NF-kappaB: a potential target for cancer chemoprevention and therapy

21 June 2018

1 reference

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TRAIL signalling: decisions between life and death.

21 June 2018

1 reference

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COMMD proteins and the control of the NF kappa B pathway

21 June 2018

1 reference

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A small molecule Smac mimic potentiates TRAIL-mediated cell death of ovarian cancer cells.

21 June 2018

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Design, synthesis, and evaluation of a potent, cell-permeable, conformationally constrained second mitochondria derived activator of caspase (Smac) mimetic.

21 June 2018

1 reference

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Constitutively activated nuclear factor-kappaB, but not induced NF-kappaB, leads to TRAIL resistance by up-regulation of X-linked inhibitor of apoptosis protein in human cancer cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Differential susceptibility to TRAIL of normal versus malignant human urothelial cells.

21 June 2018

1 reference

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APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

21 June 2018

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

COMMD proteins, a novel family of structural and functional homologs of MURR1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Mechanisms of resistance to TRAIL-induced apoptosis in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis

21 June 2018

1 reference

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mito

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Apoptosis: a link between cancer genetics and chemotherapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Targeting apoptosis in prostate cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

XIAP: apoptotic brake and promising therapeutic target.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Structural basis of IAP recognition by Smac/DIABLO

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Activators and target genes of Rel/NF-kappaB transcription factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Self-assembly of a virus-mimicking nanostructure system for efficient tumor-targeted gene delivery

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Synergy is achieved by complementation with Apo2L/TRAIL and actinomycin D in Apo2L/TRAIL-mediated apoptosis of prostate cancer cells: role of XIAP in resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Donor-acceptor (electronic) coupling in the precursor complex to organic electron transfer: intermolecular and intramolecular self-exchange between phenothiazine redox centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Simian immunodeficiency virus lentivector corrects human X-linked chronic granulomatous disease in the NOD/SCID mouse xenograft

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-9-392

Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779195

Structure-based design of potent, conformationally constrained Smac mimetics

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19895686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of the resistance to TRAIL-induced apoptosis in human primary T lymphocytes: role of NF-kappaB inhibition

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19895686

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-9-392

1 reference

Dimensions Publication ID

27 July 2017

1021896313

0 references

Fatcat ID

release_77sof5vxdfhalgdn4eg7y2qdxe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/77sof5vxdfhalgdn4eg7y2qdxe

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

2779195

1 reference

27 July 2017

1 reference