(Q33777676)

English

Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production (English)

1 reference

Europe PubMed Central

29 July 2017

1

object named as

J A Mikovits

1 reference

Europe PubMed Central

29 July 2017

Francis W. Ruscetti

10

object named as

F W Ruscetti

1 reference

Europe PubMed Central

29 July 2017

author name string

H A Young

2

1 reference

Europe PubMed Central

29 July 2017

P Vertino

3

1 reference

Europe PubMed Central

29 July 2017

J P Issa

4

1 reference

Europe PubMed Central

29 July 2017

P M Pitha

5

1 reference

Europe PubMed Central

29 July 2017

S Turcoski-Corrales

6

1 reference

Europe PubMed Central

29 July 2017

D D Taub

7

1 reference

Europe PubMed Central

29 July 2017

C L Petrow

8

1 reference

Europe PubMed Central

29 July 2017

S B Baylin

9

1 reference

Europe PubMed Central

29 July 2017

language of work or name

0 references

publication date

1 September 1998

1 reference

Europe PubMed Central

29 July 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

29 July 2017

18

1 reference

Europe PubMed Central

29 July 2017

5166-5177

1 reference

Europe PubMed Central

29 July 2017

9

1 reference

Europe PubMed Central

29 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC109102/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Molecular regulation of cytokine gene expression: interferon-gamma as a model system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

A direct role for IFN-gamma in regulation of Th1 cell development.

1 reference

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4 July 2018

De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

1 reference

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4 July 2018

Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control.

1 reference

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4 July 2018

Kinetics of cytokine expression during primary human immunodeficiency virus type 1 infection

1 reference

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4 July 2018

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

1 reference

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4 July 2018

Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.

1 reference

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Mechanisms for the involvement of DNA methylation in colon carcinogenesis

1 reference

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Comparative interleukin (IL-2)/interferon IFN-gamma and IL-4/IL-10 responses during acute infection of macaques inoculated with attenuated nef-truncated or pathogenic SICmac251 virus

1 reference

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The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells

1 reference

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CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene.

1 reference

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4 July 2018

Seminars in medicine of the Beth Israel Hospital, Boston. Pathogenesis of diseases induced by human lymphotropic virus type I infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Analysis of human immunodeficiency virus-infected tissues by amplification and in situ hybridization reveals latent and permissive infections at single-cell resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

HIV pathogenesis and long-term survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

The DNA (cytosine-5) methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

T cell cytokine responses in persons with tuberculosis and human immunodeficiency virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Quantitative analysis of CD4+ T cell function in the course of human immunodeficiency virus infection. Gradual decline of both naive and memory alloreactive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Variable course of primary simian immunodeficiency virus infection in lymph nodes: relation to disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Impaired interleukin 12 production in human immunodeficiency virus-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Virions released from cells transfected with a molecular clone of human T-cell leukemia virus type I give rise to primary and secondary infections of T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Stabilization of DNA methyltransferase levels and CpG island hypermethylation precede SV40-induced immortalization of human fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

CpNpG methylation in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Cellular and molecular mechanisms of IFN-gamma production induced by IL-2 and IL-12 in a human NK cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Methylation of the viral genome in an in vitro model of herpes simplex virus latency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Regulation of expression of the human interferon gamma gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

T4+ cell production of interferon gamma and the clinical spectrum of patients at risk for and with acquired immunodeficiency syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

5-Azacytidine up regulates the expression of Epstein-Barr virus nuclear antigen 2 (EBNA-2) through EBNA-6 and latent membrane protein in the Burkitt's lymphoma line rael

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

The role of DNA methylation in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Negative regulation of human immune deficiency virus replication in monocytes. Distinctions between restricted and latent expression in THP-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Inactivation of the HIV LTR by DNA CpG methylation: evidence for a role in latency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Transcriptional block of HTLV-I LTR by sequence-specific methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression

1 reference

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4 July 2018

Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Human T-lymphotropic virus type I transcriptional regulation by methylation

1 reference

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4 July 2018

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1 reference

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4 July 2018

Isolation and characterization of the cDNA encoding human DNA methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Abnormal regional hypermethylation in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

High frequency mutagenesis by a DNA methyltransferase

1 reference

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4 July 2018

Activation of infectious virus from latent human immunodeficiency virus infection of monocytes in vivo

1 reference

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4 July 2018

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

Interferon-gamma gene expression in human B-cell lines: induction by interleukin-2, protein kinase C activators, and possible effect of hypomethylation on gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

DNA methylation in adenovirus, adenovirus-transformed cells, and host cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

4 July 2018

5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

28 July 2018

Expression of prokaryotic HhaI DNA methyltransferase is transforming and lethal to NIH 3T3 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

30 October 2018

The natural history of HIV-1 infection: virus load and virus phenotype independent determinants of clinical course?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

30 October 2018

Hypomethylation of the interferon-gamma gene correlates with its expression by primary T-lineage cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

30 October 2018

5-Azacytidine treatment of a murine cytotoxic T cell line alters interferon-gamma gene induction by interleukin 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

30 October 2018

5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

30 October 2018

Early T-helper cell defects in HIV infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109102

30 October 2018

Increased cytosine DNA-methyltransferase activity during colon cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of interferon-gamma (IFN-gamma), IL-4 and transforming growth factor-beta (TGF-beta) mRNA expressing blood mononuclear cells in human HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV infection suppresses type 1 lymphokine and IL-12 responses to Toxoplasma gondii but fails to inhibit the synthesis of other parasite-induced monokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single cell analysis of IL-4 and IFN-gamma production by T cells from HIV-infected individuals: decreased IFN-gamma in the presence of preserved IL-4 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AZT blocks down-regulation of IL-2 and IFN-gamma gene expression in HIV acutely infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypomethylation of DNA from benign and malignant human colon neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine patterns during progression to AIDS in children with perinatal HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced genomic 5-methylcytosine content in human colonic neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered production of tumour necrosis factors alpha and beta and interferon gamma by HIV-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed death of T cells in HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9710601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.18.9.5166

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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